A system for extracting and collecting a sample of a fluid of a user, comprising a sample collection device, comprising a sample container arranged to receive said sample; a cap arranged to cooperate with the sample container and having an incision mechanism movable in the cap by a triggering mechanism; a sealing mechanism; a sample extraction device, comprising a vacuum creation mechanism arranged to create vacuum in a vacuum chamber; and a valve control mechanism arranged to release the vacuum from the vacuum chamber to the sample collection device. The system simplifies collection of a fluid (e.g., blood) sample while keeping a high-quality standard for its analysis, minimizes the risk of injury due to handling the sample, reduces the risk of contamination of the collected sample, is compatible with standard blood analysers of central laboratories, requires minimal action from the user, and can collect large volumes of bodily fluid.

Provided is an auxiliary tool that makes skin administration of a micro-needle array on which a large number of micro-needles are provided as a result of a progress in fine processing technology more certain. A skin tight-binding device provided with a tight-binding band, and a hole provided on the tight-binding band, in which, when the tight-binding band is fixed to skin, the hole forms a micro-needle patch administration portion, and the skin tight-binding device further provided with a fixing tool that fixes the tight-binding band to the skin.

Methods, devices, systems and kits for obtaining blood samples are provided. Devices include a cuff, a pressure source, and a timing mechanism. Devices may further include one or more of a: warming mechanism, lancing mechanism; automated sample collection device, automated sample analysis device, and communication unit. Systems include such a device, and may include sample collection, sample analysis, or communication devices.

Methods include placing a cuff on a digit of a subject, inflating the cuff, and obtaining a small volume blood sample. Methods may further include warming a digit; lancing a digit; pulsing the cuff; and providing a signal indicating the end of the sample collection time period.

Kits may include a device, a sample collection vessel, and may include a disposable for use in sample collection.

These methods, devices, systems and kits for obtaining blood samples may be used to easily, reliably, and consistently obtain blood samples from subjects.

A blood sample collection device can provide for collection, storage, amplification, and analysis of a blood sample in a simple, disposable device. The device can include a collection zone for drawing (e.g., via a needle array) or receiving a blood sample, a processing zone for storing and processing blood cells of the blood sample, and a filtration zone for selectively directing the blood cells of the blood sample to an array of wells within the processing zone while leading blood plasma away from the array of wells. Within the wells, which may be prepared to include materials for amplification and various assays, the blood cells can undergo amplification. Externally applied light and/or heat can facilitate amplification. A transparent or translucent window or portion of the collection device can allow an analysis device to take measurements of the array of wells without removing the sample.

An automated fluid sample collector includes: a collection receptacle; an actuator; and a piercing element coupled to the actuator. An automated sample collection device includes: a sample receptacle; a needle that is able to extend into the sample receptacle; an actuator coupled to the needle such that the actuator is able to extend and retract the needle; and a fluid chip coupled to the sample receptacle, the fluid chip able to accommodate an amount of collected fluid. An automated method of collecting a fluid sample includes: activating a pump associated with a finger retention element in order to add fluid to the finger retention element; extending an actuator associated with a piercing element; opening a pinch valve; activating a collection pump; deactivating the collection pump; closing the pinch valve; and releasing fluid from the finger retention element.

A device and method for collecting blood from an anatomical feature of a mammalian subject, the device including a vibrating plate assembly structured and arranged to retain the anatomical feature, a first biasing device releasably attachable to the vibrating plate assembly, a housing portion releasably connectable to the vibrating plate assembly, and a plurality of vibrating motors located beneath the vibrating plate assembly, such that vibrations translated to the anatomical feature enhance blood collection, such that the first biasing device constricts blood flow to the collection point on the anatomical feature, causing blood to pool therein, and low frequency and/or high amplitude vibrations cause vasodilation, encouraging blood flow through the capillaries at the collection point.

Provided are a blood sample guiding instrument and a blood test kit which enable blood ejected from a finger to be guided to a storing instrument. A blood sample guiding instrument used in a blood test kit includes a cylindrical body in which a first opening and a second opening communicating with the first opening are defined and which comes into contact with a finger; and a clamping portion that is attached to an outer circumferential surface of the cylindrical body, clamps a finger, and presses the cylindrical body against the finger.

A vacuum assisted lancing system can include a tubular body having a vacuum chamber, a lancing mechanism configured to removably couple with a lance, a vacuum mechanism including a piston slideably coupled within the body, a release mechanism for selectively holding the vacuum mechanism in an energized state and an opening for allowing fluid communication between the vacuum chamber and an atmosphere. A method of manipulating a surface for blood extraction can include coupling a lancing system to the surface, blocking an opening, creating a vacuum, moving a lance coupler from a first position distal from the surface to a second position proximal to the surface, maintaining the vacuum for a period of time and commencing dissipation of the vacuum by unblocking the opening.

A device and method for collecting blood from an anatomical feature of a mammalian subject, the device including a vibrating plate assembly structured and arranged to retain the anatomical feature, a first biasing device releasably attachable to the vibrating plate assembly, a housing portion releasably connectable to the vibrating plate assembly, and a plurality of vibrating motors located beneath the vibrating plate assembly, such that vibrations translated to the anatomical feature enhance blood collection, such that the first biasing device constricts blood flow to the collection point on the anatomical feature, causing blood to pool therein, and low frequency and/or high amplitude vibrations cause vasodilation, encouraging blood flow through the capillaries at the collection point.

Devices are provided to automatically inject drugs or other payloads into or beneath skin. These devices include an injector configured to drive a hollow needle into the skin and subsequently to deliver the payload through the hollow needle. Applied suction acts to draw blood from the puncture formed in the skin through the hollow needle, into the device, and to a sensor, blood storage element, or other payload. In some examples, the blood is drawn through the hollow needle when the hollow needle is penetrating the skin. In some examples, these devices are additionally configured to retract the hollow needle from the skin and/or to perform some other functions. These devices can be wearable and configured to automatically access blood or deliver a payload into skin, for example, to operate at one or more points in time while a wearer of a device is sleeping.