A lancing device includes a housing, a lancing unit capable of reciprocating relative to the housing, an elastic member for causing the lancing unit to reciprocate, and a resistance generator for applying resistance to the lancing unit in motion. The reciprocating motion of the lancing unit includes a puncture section or interval and a retreat section following the puncture section. The puncture section includes a puncture point at which a lancing element of the lancing unit can prick the skin of a human subject, for example. The resistance generator is configured to apply a greater resistance to the lancing unit in the retreat section than in the puncture section.

A medical puncturing device having a wicking element disposed on a portion of the medical puncturing device is disclosed. The wicking element allows a user to remove a first drop of blood upon puncturing the skin using the medical puncturing device. In this manner, a subsequent drop of blood can be used to test their blood to determine their blood glucose level for proper insulin dosing.

A portable medical apparatus including at least a sampling assembly for providing at least one sample of a fluid in an object, a detector for determining at least one parameter of the fluid, an injector for performing at least one injection of an injection medium, and which are operable independent of each other for improved self-treatment of diseases such as diabetes. The portable medical apparatus has a single common housing for these components and a switch for changing between the sampling mode, the determining mode, and the injection mode. The apparatus also includes an actuator means for individually actuating the other components. The apparatus is an all-in-one device that facilitates the medical treatment process for patients, medical professionals or others.

The biological test kit is a device for drawing and, optionally, testing biological samples. The biological test kit is an array of lancets set in wells in a rigid base. Each lancet well is covered by a protective cover which when deformed permits the lancet to puncture a user or other patient. In one embodiment the biological test kit employs distinct covers for each lancet and in another the covers are formed from sheet material formed into blisters which cover the lancet.

A medical device including a housing, and a diagnostic cartridge removably coupled to the housing, the diagnostic cartridge including a retractable needle mechanism disposed within the diagnostic cartridge, the retractable needle mechanism configured to extract a fluid sample, a fluid collection chamber disposed the retractable needle mechanism, the fluid collection chamber configured to collect the fluid sample extracted by the retractable needle mechanism, and a diagnostic chip disposed within the fluid collection chamber configured to analyze the fluid sample.

Embodiments of the present disclosure generally relate to apparatuses for sampling bodily fluids and methods of fabrication thereof. The apparatus includes at least one adhesive patch, at least one bodily fluid port attached to the adhesive patch, and at least one bodily fluid storing capillary connected to the bodily fluid port and attached to the adhesive patch. The adhesive patch may be adhered to a subject's skin, the input port may then be connected to a source of bodily fluids and the one or more bodily fluid storing capillaries function to draw in the bodily fluid over time and store it for later analyzation. The one or more bodily fluid storing capillaries may be formed by imprint lithography on a plastic or glass substrate.

The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication.

A one-time/single use safety lancet system includes a body; a spring coupled to the body; a keeper having a deformable member; and a core for supporting a lancet and having an end coupled to the spring. The core further has a first latch for engaging the deformable member when the lancet system is in an armed state. The deformable member of the keeper is fractured after one use of the lancet system which prevents any subsequent arming of the lancet system. The keeper may be made part of the lancet body. The core may include a second latch, wherein the second latch permanently deforms or fractures the deformable member of the keeper after the single, one-time arming of the safety lancet system.

Devices are provided to automatically access blood from beneath or within skin. These devices include an injector configured to drive a needle into the skin and subsequently to retract the needle from the skin. These devices additionally include a seal to which suction is applied. To drive the needle into the skin, the needle is first driven through the seal, creating at least one hole in the seal. The suction applied to the seal acts to draw blood from the puncture formed in the skin by the needle, through the at least one hole in the seal, and to a sensor, blood storage element, or other payload. These devices can be wearable and configured to automatically access blood from skin, for example, to access blood from the skin at one or more points in time while a wearer of a device is sleeping.

The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member. Other aspects of the present invention are directed at other devices for receiving blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.