Systems, methods, and non-transitory computer-readable storage media for gathering activity data describing a user's activities from one or more activity sensors and using the activity data to predict immune-response to the activity. Predicting immune-response can involve creating, personalizing, and refining immune-response prediction models based on demographic user data, activity data, blood sample data, personal genetic information.

A lancing device has a domed structure that can be depressed by application of a force by a user's finger so as to expose the tip of a needle. The domed structure is configured to move from a non-depressed state to a depressed state in a manner that allows for the piercing of the user's finger. The domed structure may then recoil to its original, non-depressed position upon the user ceasing to apply the force. Other embodiments of a lancing device are disclosed.

Disclosed are devices, kits, compositions, and methods for collecting, transporting, and detecting toxicants, pathogens, and biomarkers in a biological sample. The devices, kits, compositions and methods may be utilized to collect and transport dried blood samples from a skin prick and detect toxicants, pathogens, and biomarkers in the dried blood samples.

The disclosure relates to a skin piercing tool for locally puncturing a human or an animal skin, comprising a piercing needle, which is embodied as solid needle, in the case of which a needle body has a proximal needle section and a distal needle section, in which a piercing tip is arranged, wherein the needle body has a needle section, which is resilient against the piercing tip in response to a compressive stress, wherein the resilient needle section is arranged on the needle body in the area of an angled needle section, in which adjacent needle sections assume an angle of less than 180 with one another. Further, a hand-held device for repeated local puncturing of a human or an animal skin is provided.

A suction applying device (10) for applying suction to a sampling unit (50) for sampling bodily fluid, wherein the suction applying device comprises a syringe body (12) with a hollow interior (14) and a piston (20) movable inside the hollow interior of the syringe body. The syringe body has a rear end (16) through which a piston rod (21) connected to the piston extends outside of the syringe body and by means of which the piston can be moved, and a front end (18) opposite the rear end. The suction applying device further comprises a connection arrangement (130) configured for connection of a sampling unit, wherein the connection arrangement is located at the front end of the syringe body. The suction applying device also comprises a first conduit (40) having a rear opening (41) connecting the first conduit to a rear portion (14b) of the hollow interior, in which rear portion a sub-pressure is created when the piston is moved forward inside the hollow interior, and a front opening (42) by means of which the first conduit is connectable to a sampling unit. The suction applying device also comprises a second conduit (46) that connects a front portion (14a) of the hollow interior with the exterior of the syringe body, and which front portion is located between the piston and the front end of the syringe body. Also disclosed is an apparatus for sampling bodily fluid, comprising a suction applying device and a sampling unit, as well as a method for detecting a component in a bodily fluid.

Various collection devices, systems and methods relating to the use of devices with open microfluidic channels disposed within a housing defining a lumen. These devices make use of microneedles passed through apertures to induce fluid flow into microfluidic channel networks for collection and analysis. The device can be actuated via button when placed on the skin of a patient to collect a fluid sample, such as a blood draw.

The biological test kit is a device for drawing and, optionally, testing biological samples. The biological test kit is an array of lancets set in wells in a rigid base. Each lancet well is covered by a protective cover which when deformed permits the lancet to puncture a user or other patient. In one embodiment the biological test kit employs distinct covers for each lancet and in another the covers are formed from sheet material formed into blisters which cover the lancet.

Systems, methods, and non-transitory computer-readable storage media for gathering activity data describing a user's activities from one or more activity sensors and using the activity data to predict immune-response to the activity. Predicting immune-response can involve creating, personalizing, and refining immune-response prediction models based on demographic user data, activity data, blood sample data, personal genetic information.

A lancing device having a domed structure that can be depressed by application of a force by a user's finger so as to expose the tip of a needle. The domed structure is configured to move from a non-depressed state to a depressed state in a manner that allows for the piercing the users finger. The domed structure may then recoil to its original, non-depressed position upon the user ceasing to apply the force.

The present invention relates to the field of test devices. The skin prick test device according the present invention mainly comprises conjoined bottles, a tray and pricking devices, wherein each set of conjoined bottles, which comprises a large bottle body and a small bottle body, is arranged in clamping holes of the tray, and liquid medicine can flow into the small bottle body from the large bottle body through an inclined surface, thereby avoiding frequent refilling of the liquid medicine. In addition, each connecting base has a trapezoidal cross section with its bottom surface being flush with that of the holder, and is gradually widened from the top down to fit with the parallel clamp plates on the tray, so that the pricking device has better stability as both ends thereof are prevented from excessively shaking longitudinally when the pricking device is taken out of and put into the tray.