Various collection devices, systems and methods relating to the use of devices with open microfluidic channels disposed within a housing defining a lumen. These devices make use of microneedles passed through apertures to induce fluid flow into microfluidic channel networks for collection and analysis. The device can be actuated via button when placed on the skin of a patient to collect a fluid sample, such as a blood draw.

Disclosed herein are devices, apparatus, systems, methods and kits for collecting and storing a fluid sample from a subject. A device for collecting the fluid sample can include a housing comprising a recess having an opening, a vacuum chamber in the housing and in fluidic communication with the recess, and one or more piercing elements that are extendable through the opening to penetrate skin of the subject. The vacuum chamber can be configured for having a vacuum that draws the skin into the recess. The recess can be configured having a size or shape that enables an increased volume of the fluid sample to be accumulated in the skin drawn into the recess.

Methods and apparatus are provided for manufacturing an analyte detecting device. In one embodiment, the apparatus comprises a housing; a penetrating member driver; a cartridge containing a plurality of penetrating members; a display on the cartridge; a linear slider on the housing, the slider coupled to a rod; and the rod moving with the slider, the rod having at least one roller. The device uses the linear motion of the slider to rotate the cartridge, punch open a new cavity and load a new penetrating member.

Fill stations and base stations are provided for personal pump systems. The fill stations may be opened and closed to accept a reservoir and to allow fluid to be introduced into the reservoir for use with personal pump systems. The fill stations may hold the reservoir at a tilt relative to an underlying surface and may discourage overfilling of the reservoir. The filling stations may also include viewing windows having fluid lines marked thereon for indicating volume of fluid within the reservoir.

A system is disclosed. The system includes a reservoir for containing a fluidic medium, the reservoir including a front surface, a resilient cylindrical flexure portion connected to the front surface, the resilient cylindrical flexure portion comprising an accordion-like structure that is able to expand and contract to change an interior volume within the resilient cylindrical flexure portion, a central passageway within the resilient cylindrical flexure, and a collection chamber connected to the central passageway. Also, a system including a reservoir, a plunger head located within the reservoir, a plunger arm connected to the plunger head, a driving shaft connected to the plunger arm, and a motor connected to the driving shaft, the motor controllable to move the drive shaft in a first motion and a second motion so as to move the advance plunger head and retract the plunger head within the reservoir.

A blood sampling device includes a housing and a lancet supporting a lancet needle or tip, the lancet and needle being urged or urgeable in a pricking direction. A trigger mechanism is moveable to a fire position for releasing the lancet to travel in the pricking direction. A removable safety cap initially covers the lancet needle. The lancet has an initial position in which movement of the trigger mechanism to the fire position is blocked and an intermediate position in which the trigger mechanism may be moved to the fire position. The intermediate position is obtainable only on removal of the safety cap.

Described here are meters and methods for sampling, transporting, and/or analyzing a fluid sample. The meters may include a meter housing and a cartridge. In some instances, the meter may include a tower which may engage one or more portions of a cartridge. The meter housing may include an imaging system, which may or may not be included in the tower. The cartridge may include one or more sampling arrangements, which may be configured to collect a fluid sample from a sampling site. A sampling arrangement may include a skin-penetration member, a hub, and a quantification member.

A lancing device includes: a cover section, a part of which is provided with an opening; a main body held on the cover section and configured to be movable in a predetermined direction from the opening relative to the cover section; a lancing unit which is launched in the predetermined direction; and an operating section configured to launch the lancing unit when the operating section is pushed by applying a force in the predetermined direction, wherein the lancing unit is launched when the force is applied to the operating section in the predetermined direction with regulating a movement of the main body in the predetermined direction, and the main body moves, instead of pushing the operating section, by applying the force in the predetermined direction without regulating the movement of the main body in the predetermined direction is disclosed.

A blood analyzer device has a housing with a top section coupled to a bottom section, a driver and a plurality of penetrating members housed in a disposable positionable in the housing. A gripper engages each penetrating member. A manually actuated button advances the disposable to move penetrating members into launch positions. A power is source coupled to the driver. A display is at the housing.

A lancing device includes a housing, a lancing unit capable of reciprocating relative to the housing, an elastic member for causing the lancing unit to reciprocate, and a resistance generator for applying resistance to the lancing unit in motion. The reciprocating motion of the lancing unit includes a puncture section or interval and a retreat section following the puncture section. The puncture section includes a puncture point at which a lancing element of the lancing unit can prick the skin of a human subject, for example. The resistance generator is configured to apply a greater resistance to the lancing unit in the retreat section than in the puncture section.