Systems, methods and devices for reducing noise in health monitoring including monitoring systems, methods and/or devices receiving a health signal and/or having at least one electrode and/or sensor for health monitoring.

A monitor recorder-implemented method for electrocardiography data compression and an electrocardiography monitor recorder with integral data compression are provided. A series of data items are obtained, each of the data items associated with a magnitude of an ECG signal sensed by a monitor recorder. A range is set for an initial one of the data items in the series. Each of the data items remaining in the series is processed, including: obtaining an estimation of probabilities of the data items appearing next to that data item in the series; dividing the further range into sub-ranges, each sub-range representing a fraction of the further range proportional to the probabilities of the next data items; selecting the sub-range corresponding to the data item next to that data item in the series; and representing the next data item by the selected sub-range in a non-volatile memory.

Disclosed is a layered body comprising a polymer comprising repeating units having the general structure CH.sub.2CHR.sup.1COOR.sup.2 as defined herein, to a process for producing such a layered body, to a layered body produced by that process and to the use of a layered body for electrophysical measurements.

An electrophysiology map, for example a map of arrhythmic substrate, can be generated by acquiring both geometry information and electrophysiology information pertaining to an anatomical region, and associating the acquired geometry and electrophysiology information as a plurality of electrophysiology data points. A user can select two (or more) electrophysiological characteristics for display, and can further elect to apply various filters to the selected electrophysiological characteristics. The user can also define various relationships (e.g., Boolean ANDS, ORs, and the like) between the selected and/or filtered characteristics. The user-selected filtering criteria can be applied to the electrophysiology data points to output various subsets thereof. These subsets can then be graphically rendered using various combinations of colorscale, monochrome scale, and iconography, for example as a three-dimensional cardiac electrophysiology model.

The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.

Articles and methods of making articles are described. In one embodiment, an electrode is described, comprising an ionically-conductive hydrogel layer comprising a first major surface and opposing major surface. The electrode further comprises a discontinuous primer layer disposed on the first major surface ionically-conducting hydrogel layer and an electrically conductive member or a connector component thereof, in contact with the first major surface of the ionically-conducting hydrogel layer. In another embodiment, an article is described comprising a hydrogel layer comprising a first major surface and opposing major surface; a discontinuous hydrophobic primer layer disposed on the first hydrogel layer; and a hydrophobic adhesive or hydrophobic backing bonded to the primer and discontinuous hydrophobic primer layer of the hydrogel.

Disclosed are systems and methods for using one or more light sources and associated photodetectors to determine different physiological parameters of a subject based on the subject's activity state. A processor may, for example, be configured to determine, based at least in part on data received from an accelerometer at a first time, that a first physiological parameter of the subject is to be determined, to cause the light source(s) to operate in a first manner and process signals from the photodetector(s) to determine the first physiological parameter, to determine, based at least in part on data received from the accelerometer at a second time, that a second physiological parameter of the subject is to be determined, and to cause the light source(s) to operate in a second manner and process signals from the photodetector(s) to determine the second physiological parameter.

A biosensor includes a pressure-sensitive adhesive layer for attaching to a surface of a living body, a substrate layer disposed on an upper face of the pressure-sensitive adhesive layer and having a stretching property, a probe disposed on the lower face of the pressure-sensitive adhesive layer, and an electronic component mounted on the substrate layer so as to be connected to the probe, wherein a total thickness of the pressure-sensitive adhesive layer and the substrate layer is 1 m or more and less than 100 m.

An electrocardiographic system, the electrocardiographic system includes a first part that includes: a first housing that comprises of a first bottom layer that is elastic and has an underside provided with an adhesive material; a first set of electrodes that is located within the first housing; wherein the first set of electrodes comprises at least one first electrode; a second part that comprises: a second housing that comprises a second bottom layer that has an underside provided with an adhesive material; a second set of electrodes that are located within the second housing; wherein the second set of electrodes comprises at least one second electrode; a mechanical adaptor that is arranged to be detachably connected to a electrocardiographic device that comprises a processor and a wireless transmitter; and an electrical connector that is detachably is arranged to be detachably connected to the electrocardiographic device and to electrically couple the electrocardiographic device to conductors that convey signals from the first and second sets of electrodes.

Physiological monitoring can be provided through a lightweight wearable monitor that includes two components, a flexible extended wear electrode patch and a reusable monitor recorder that removably snaps into a receptacle on the electrode patch. The wearable monitor sits centrally on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline, with its unique narrow hourglass-like shape, significantly improves the ability of the wearable monitor to cutaneously sense cardiac electrical potential signals, particularly the P-wave and the QRS interval signals indicating ventricular activity in the ECG waveforms. In particular, the ECG electrodes on the electrode patch are tailored to be positioned axially along the midline of the sternum for capturing action potential propagation in an orientation that corresponds to the aVF lead used in a conventional 12-lead ECG that is used to sense positive or upright P-waves.