A blood pressure (BP) measuring device including a PPG sensor, having one or more light sources and one or more light detectors; a computing unit, including a receiver for receiving PPG signals from the PPG sensor and a sampling circuit, for generating PPG signals samples of the PPG signals, where the device also includes a processor having BP calculation functionality, for processing the PPG signals samples into sequential BP values and a BP output unit, for outputting the calculated BP values, where the sampling circuit is adapted to sample at high sampling rate and provide BP values at a rate higher than 1 BP value per second, where the device may also include an electrogram sensor, having one or more electrodes for outputting tissue electrical activity values, the computing unit is connected to the electrogram sensor.

A blood pressure (BP) measuring device including a PPG sensor, having one or more light sources and one or more light detectors; a computing unit, including a receiver for receiving PPG signals from the PPG sensor and a sampling circuit, for generating PPG signals samples of the PPG signals, where the device also includes a processor having BP calculation functionality, for processing the PPG signals samples into sequential BP values and a BP output unit, for outputting the calculated BP values, where the sampling circuit is adapted to sample at high sampling rate and provide BP values at a rate higher than 1 BP value per second, where the device may also include an electrogram sensor, having one or more electrodes for outputting tissue electrical activity values, the computing unit is connected to the electrogram sensor.

A system for monitoring vital signs, configured to be used in conjunction with a computerized mobile device, the system including: a cover sensor assembly adapted to be operably engaged with the computerized mobile device, the cover sensor assembly having integrated therein at least one physiological sensor; a physiological data acquisition module configured to generate a physiological parameter measurement descriptive of a physical stimulus received by the at least one physiological sensor; and a validation module configured to control a validity status of the physiological parameter measurement.

A system for monitoring vital signs, configured to be used in conjunction with a computerized mobile device, the system including: a cover sensor assembly adapted to be operably engaged with the computerized mobile device, the cover sensor assembly having integrated therein at least one physiological sensor; a physiological data acquisition module configured to generate a physiological parameter measurement descriptive of a physical stimulus received by the at least one physiological sensor; and a validation module configured to control a validity status of the physiological parameter measurement.

An electrocardiogram waveform measurement system is configured to be suitable for measuring an electrocardiogram waveform with high precision using multiple electrodes provided to an article of clothing. A measurement unit performs measurement in a state in which multiple fabric electrodes are grouped into multiple channels. A signal measured by the electrodes for each channel is evaluated in a two-dimensional manner based on the number of times an R wave is detected by an R wave processing unit in a predetermined period of time and a degree of data concentration in a dynamic range acquired by a degree-of-concentration calculation unit. A channel selection unit selects the optimum channel.

An electrocardiogram waveform measurement system is configured to be suitable for measuring an electrocardiogram waveform with high precision using multiple electrodes provided to an article of clothing. A measurement unit performs measurement in a state in which multiple fabric electrodes are grouped into multiple channels. A signal measured by the electrodes for each channel is evaluated in a two-dimensional manner based on the number of times an R wave is detected by an R wave processing unit in a predetermined period of time and a degree of data concentration in a dynamic range acquired by a degree-of-concentration calculation unit. A channel selection unit selects the optimum channel.

An electrode multiplexing physiological parameter monitoring ring, comprising a built-in power supply (2), a microprocessor module (1), an electrocardiogram monitoring analog front end (3), a skin conductance monitoring module (4), a first electrode (6), and a second electrode (7). The microprocessor module (1) is connected to the electrocardiogram monitoring analog front end (3) and the skin conductance monitoring module (4). The first electrode (6) and the second electrode (7) are connected to the electrocardiogram monitoring analog front end (3), and the electrocardiogram monitoring analog front end (3) processes electrocardiogram signals collected by the first electrode (6) and the second electrode (7). The first electrode (6) and the second electrode (7) are further connected to the skin conductance monitoring module (4), and the skin conductance monitoring module (4) processes skin impedance signals collected by the first electrode (6) and the second electrode (7). A coupling manner in which the first electrode (6) and the second electrode (7) are coupled to the electrocardiogram monitoring analog front end (3) is direct current coupling or alternating current coupling, and is opposite to a coupling manner in which the first electrode (6) and the second electrode (7) are coupled to the skin conductance monitoring module (4). By means of the electrode multiplexing physiological parameter monitoring ring, electrocardiogram monitoring, heart rate monitoring, and skin conductance monitoring are implemented through only two electrodes, so that the number of electrodes is reduced, and system design is simplified.

Systems and methods for graph total variation (GTV) based reconstruction of electrical potentials on a cardiac surface are disclosed. GTV-based systems and methods incorporate information about the graph structure of the heart surface as well as imposing sparsity constraints on neighboring nodes. To this end, the present disclosure uses a novel way of calculating derivatives on irregular meshes, and provides a fast solver to compute an inverse solution more efficiently than in previous systems and methods. Moreover, fast-changing signals can be recovered with less smoothing and thus greater fidelity to the original signals.

A method includes receiving analog body-surface signal from body-surface electrode, and multiple analog unipolar signals from multiple unipolar electrodes of an invasive probe. A first unipolar electrode is assigned to serve as a common electrical ground and a common timing reference for the analog unipolar signals and the analog body-surface signal. The analog unipolar signals are digitized to produce digital unipolar signals sampled relative to a digital ground. Defined are an analog bipolar signal between the first unipolar electrode and a second unipolar electrode of the probe, and digital bipolar signal formed from the first unipolar electrode and the second unipolar electrode. Ground and timing offsets between the analog bipolar signal and the digital bipolar signal are estimated, while the first unipolar electrode is connected to the digital ground. The ground offset and the timing offset are applied in measuring a third unipolar signal, sensed by a third unipolar electrode.

A method includes receiving analog body-surface signal from body-surface electrode, and multiple analog unipolar signals from multiple unipolar electrodes of an invasive probe. A first unipolar electrode is assigned to serve as a common electrical ground and a common timing reference for the analog unipolar signals and the analog body-surface signal. The analog unipolar signals are digitized to produce digital unipolar signals sampled relative to a digital ground. Defined are an analog bipolar signal between the first unipolar electrode and a second unipolar electrode of the probe, and digital bipolar signal formed from the first unipolar electrode and the second unipolar electrode. Ground and timing offsets between the analog bipolar signal and the digital bipolar signal are estimated, while the first unipolar electrode is connected to the digital ground. The ground offset and the timing offset are applied in measuring a third unipolar signal, sensed by a third unipolar electrode.