The inventive concept refers to a system, a method, and a computer program for providing training for pain improvement. According to an exemplary embodiment, a training providing method for pain improvement includes requesting, by a computer, a temperature providing device to provide a first temperature to a first body point, requesting, by the computer, the temperature providing device to provide a second temperature to a second body point, requesting a user to select a temperature matched with a specific condition among the first temperature and the second temperature, and calculating a correct answer rate after performing a trial of distinguishing between the first temperature and the second temperature by a predetermined number.

A diagnostic system includes an array of electrodes, which are coupled to a body surface of a living subject at different, respective positions in proximity to a region of interest within the body. A switched impedance network applies varying loads to the electrodes. A processor is coupled to receive and measure electrical signals from the electrodes as a function of the varying loads, and to analyze the measured signals so as to compute a local electrical characteristic of one or more locations within the region of interest.

Provided are compositions and methods for detecting and modulating oscillatory patterns within the basolateral amygdala (BLA) for diagnosis and treatment of anxiety related disorders.

The system and methods described herein determine a subject's indication of attention to a first and a second sensory stimuli. The system determines a sensory evoked response of the subject by calculating the statistical relationship between the subject's neural response to the stimuli and a signal feature of the first and the second sensory stimuli. A magnitude value of the sensory evoked response is extracted to determine whether the subject attended-to or ignored the sensory stimuli. The system will select the stimuli that elicited the greater indication of attention, and then trigger further processing by a computer. Such processing can include selecting future content for improving safety warnings, educational materials, or advertisements or further processing can include controlling and navigating a brain computer user interface.

The present application provides for use of a somatosensory evoked potential (SEP) during the hyperacute stroke phase as marker for predicting the outcome of endovascular treatment in a patient suffering from acute ischemic stroke, wherein when the SEP ipsilateral to the stroke site has an amplitude from 60% to 100% with respect to the corresponding SEP contralateral to the stroke site this is indicative of good outcome of the endovascular treatment, whereas when the SEP ipsilateral to the stroke site has an amplitude from 0% to 20% with respect to the corresponding SEP contralateral to the stroke site this is indicative of bad outcome of the endovascular treatment.

The present application provides for use of a somatosensory evoked potential (SEP) during the hyperacute stroke phase as marker for predicting the outcome of endovascular treatment in a patient suffering from acute ischemic stroke, wherein when the SEP ipsilateral to the stroke site has an amplitude from 60% to 100% with respect to the corresponding SEP contralateral to the stroke site this is indicative of good outcome of the endovascular treatment, whereas when the SEP ipsilateral to the stroke site has an amplitude from 0% to 20% with respect to the corresponding SEP contralateral to the stroke site this is indicative of bad outcome of the endovascular treatment.

A system provides a burr hole cap assembly configured to secure a position of a lead implanted through a burr hole in a cranium of a patient. One or more electrodes are coupled to one or more components of the burr hole cap assembly. The one or more electrode is disposed within the burr hole cap assembly for sensing signals within a brain of the patient or stimulating a portion of the brain of the patient.

A system provides a burr hole cap assembly configured to secure a position of a lead implanted through a burr hole in a cranium of a patient. One or more electrodes are coupled to one or more components of the burr hole cap assembly. The one or more electrode is disposed within the burr hole cap assembly for sensing signals within a brain of the patient or stimulating a portion of the brain of the patient.

Systems, devices and methods are provided for conducting a pain management therapy session, which includes performing a BCI training session utilizing feedback to train a subject to generate defined brain signals to assist the subject in managing and/or relieving pain, and applying a stimulus to the subject, in connection with the BCI training session, at a location that is near the source of pain and/or within the nervous system pain pathway to the source of pain.

A system for evaluating neurologic dysfunction of a subject includes an odorant generator configured to deliver an odorant stimulation to the subject, an auditory generator configured to deliver an audible stimulation to the subject, a vibrotactile stimulator configured to generate a somatosensory stimulation to the subject, a plurality of electrodes configured to be attached to the subject at respective different locations, and at least one processor. The plurality of electrodes are configured to collect neural signals from the subject as a result of the odorant stimulation, the audible stimulation, and the somatosensory stimulation. The at least one processor is configured to process the neural signals from the plurality of electrodes and generate an assessment of neurologic dysfunction of the subject.