A system for generating occlusal loading is provided, including a loading appliance and a controller. The loading appliance includes three load transmission elements and three actuators. The load transmission elements are adapted to be positioned between upper and lower anterior teeth of the patient and between upper and lower posterior teeth on the left and right sides of the patient's mouth, respectively. The load transmission elements are separated from each other. The actuators are coupled to the load transmission elements, respectively. The controller is configured to control the three actuators to actuate the three load transmission elements individually and sequentially, with a rest period between successive actions of the three load transmission elements, to transmit vibration energy from the three actuators to the patient's periodontal tissues of the anterior teeth, the left posterior teeth, and the right posterior teeth.

A biological information measuring device (100a) includes a light source configured to emit probe light; a total reflection member (16) configured to totally reflect the probe light with the total reflection member (16) brought into contact with a subject (S) to be measured; a light intensity detector configured to detect light intensity of the probe light reflected from the total reflection member (16); a biological information output unit (2a) configured to output biological information, the biological information being acquired based on the light intensity; and a display unit (506) configured to display the light intensity or an absorbance of the probe light, the absorbance being acquired based on the light intensity. Preferably a pressure detector is provided configured to detect a pressure of the subject (S) with respect to the total reflection member (16).

Disclosed is an IoT enabled, portable, multiple stimuli reinforced non-nutritive Sucking Training System, Method and Device that implements a function that measures suction pressure of a non-nutritive sucking event produced by a pre-mature infant; then converts the measured pressure value using transducer to digital form; then transmits the pressure value in digital form using IoT (Internet-of-Things) controller to a server and/or to an app and/or a software installed on a smartphone device. The app and/or software installed on the smartphone device which receives the pressure measurement uses an algorithm to produce a stimulus such as music and/or haptic feedback for the pre-mature infant, to train the premature infant to suck optimally; thereby improving self-feeding capability of the premature infant.

To provide a mask capable of reducing a load of a patient while suppressing lowering of accuracy at which a subject's exhaled air is measured. A mask to be put on a subject's face includes a mask body portion demarcating an internal space in a state of covering part of the subject's face and a cup-shaped nasal cup covering a subject's nose in a state of being arranged inside the internal space, in which the nasal cup includes a first wall portion covering the subject's nose, a second wall portion arranged under the subject's nostrils, and an exhaled air discharge portion guiding an exhaled air from the subject's nose to an exhaled air sensor, and at least part of the exhaled air from the subject's nose is guided toward the exhaled air discharge portion by the second guide portion in a state where the nasal cup covers the subject's nose.

An oral insert includes at least one pH sensor in electronic communication with a power source and a data transceiver. The pH sensor is exposed to fluids in the patient's mouth and measures the pH of the fluids to determine fluid composition.

A system and method for measuring the effectiveness of a dose from an inhaler on a user is disclosed. The inhaler includes a drug container and a dosing mechanism coupled to the drug container to aerate a dose from the drug container. The dosing mechanism provides the aerated dose to the user. A sensor interface is in communication with a physiological sensor. The physiological sensor is attached to a user to sense a physiological response to the dose. Physiological data is sent to the sensor interface. A controller is coupled to the sensor interface to collect the sensed physiological data from the user corresponding to the time that the aerated dose is delivered to the user. The effectiveness of the dose may be determined from the collected data. The dose amount or frequency may be changed or the drug may be changed based on the collected data.

A pharmaceutical composition for treating an influenza virus infectious disease, containing an anti-influenza virus agent as an active ingredient is provided. The anti-influenza virus agent is administered to a patient determined to be positive for the influenza virus infectious disease based on an intraoral image captured using an intraoral imaging apparatus.

A non-invasive method for determining a gingival pocket depth includes seating a photoacoustic probe tray in a subject's mouth; transmitting photonic energy transgingivally; receiving generated ultrasonic signals; determining and processing the time of flight between transmitting and receiving and a relative amplitude of the ultrasonic signals to the transmitted photonic energy to determine densities and a topography of the subject's dental anatomy; determining a repeatable reference point; and measuring the gingival pocket depth in relation to the repeatable reference point. A system includes a transducer tray a biogel-containing bite wafer seated within the transducer tray; a processor; a memory; a user interface; and a visual display. The transducer tray has at least one embedded pulsed laser source and at least one embedded ultrasonic sensor.

Disclosed is a system for evaluating brain trauma via regional changes in tissue impedance. The present disclosure describes a system for non-invasive intracranial monitoring, comprising two or more affecting electrodes arranged between a conductive location of a cranium of a patient and a location on a scalp of the patient, two or more effected electrodes arranged between the conductive location of the cranium of the patient and the location on the scalp of the patient, and processing circuitry configured to apply an electrical stimulus between the two or more affecting electrodes, measure an electrical stimulus differential between the two or more effected electrodes, calculate, for the two or more effected electrodes, a value of an impedance metric, and identify, based on the calculated value of the impedance metric, a health condition of the patient.

An electronic cigarette and a wearable electronic device which can function together or separately are disclosed. The electronic cigarette includes a communication interface, a controller, a heat generator, and a power supply. The wearable electronic device includes a sensor, a controller, and a communication interface. The electronic cigarette and the wearable electronic device can cooperatively work. Data can be exchanged between the electronic cigarette and the wearable electronic device and each can process the received data, thereby controlling the electronic cigarette to operate in certain manners. The electronic cigarette can function with greater intelligence and with more diversity.