A lacrimal tear flow measurement device, and methods of manufacture and use, are described that includes a polymer microcapillary tube or similar structure having at least one end coated on the outside with soft silicone rubber and one end treated on the inside to be hydrophobic. The hydrophobic end keeps liquid from escaping or entering that end while allowing air to pass. The rest of the tube's insides may be hydrophilic or a neutral hydrophobe. As a Schirmer's test strip replacement, the entrance end of the device can be touched to the lacrimal lake of a patient's eye to collect suck up, or merely collect, tear fluid within the collection tube for weighing, volume measurement, or other analysis. Long-term collection devices for wear between doctors' visits can have a bypass channel allowing liquid to flow back onto the eye.

A biosensing composition having sensing glucose content is provided, including a substrate, glucose oxidase, an antioxidant, heme-protein, and a molecular chromogenic chromophore. In addition, a contact lens having sensing glucose content and a method of preparation thereof are provided, so as to achieve the effect of maintaining a low discoloration in normal blood sugar and obvious discoloration in high blood sugar.

Systems configured to acquire temperature signals from an Abreu Brain Thermal Tunnel (ABTT), to analyze the temperatures signals, and to determine a condition of a human body from the analysis, and a method for doing the same, are described. In addition, systems for application of thermal signals to the ABTT for treatment of conditions are described.

Systems configured to acquire temperature signals from an Abreu Brain Thermal Tunnel (ABTT), to analyze the temperatures signals, and to determine a condition of a human body from the analysis, and a method for doing the same, are described. In addition, systems for application of thermal signals to the ABTT for treatment of conditions are described.

A system and method for non-invasively and continuously measuring an intraocular pressure, includes a wearable device designed to be worn by a user and forms an air chamber between the wearable device and the eyes of the user. The wearable device includes flexible materials to seal the air chamber around eye cavities of the user and further includes imaging sensors for collecting 2D and 3D data of the user's eyes; a pressure controller to modify an air pressure inside the air chamber with an air pump, wherein the pressure controller can be either embedded on the wearable device or is connected to the wearable device through a flexible pressure pipe; and a central controller for constructing a model of the user's eyes using 3D imaging techniques based on the collected 2D and 3D data and output intraocular pressure calculations based on the model.

A water hose coupling having a swivel grip is provided. A first coupling portion with a male threaded end integral with a first larger diameter base is connected to a second coupling portion through a freely rotating connection. The second coupling portion includes a second larger diameter base. The second coupling portion further includes a coupling protrusion integral with the second larger diameter base. The coupling protrusion may have one or more barbs to interface with a hose or a threaded female coupling to interface with a male threaded connector. The coupling is connected to an end of a hose to which accessories may be attached. An outer sleeve is connected to the first larger diameter base of the first coupling portion and can freely rotate with the first coupling portion around the remainder of the apparatus and hose. The outer sleeve acts as an ergonomic grip for users to hold and rotate when using the hose and installing accessories.

An intraocular implant device for comprehensive intraocular vision advancement includes an intraocular implant body shaped for positioning inside a lens chamber of an eye. In some embodiments, the implant includes an optical adjustable base accommodating lens configured to provide both base adjustment and accommodation. In further embodiments, the implant includes a photoelectric sensor operable to receive incident light through the cornea and to convert the received light into electrical energy for use with one or more circuit components disposed on the body, and wherein the photoelectric sensor is also operable to convert the received light into image data. The ocular implant device may include a projector for projecting the image data onto the retina of a user. The ocular implant may additionally include an autofocusing digital camera, an autofocusing electromechanical lens array, and sensors for detecting glucose levels and/or intraocular eye pressure.

An implantable intraocular physiological sensor for measuring intraocular pressure, glucose concentration in the aqueous humor, and other physiological characteristics. The implantable intraocular physiological sensor may be at least partially powered by a fuel cell, such as an electrochemical glucose fuel cell. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device. In addition, the implantable intraocular physiological sensor may incorporate aqueous drainage and/or drug delivery features.

The present invention relates to an OBP measuring and monitoring device comprising a contact lens presenting an inner surface and an outer surface and a sensing unit, said sensing unit being united with said contact lens such that it is applied against an eye of a user for sensing at least a first OBP and a second OBP of said eye when said contact lens is worn by said user, said sensing unit being adapted to measure simultaneously or consecutively the first and second OBPs and transmit these OBPs to a CPU such that said CPU receiving said measurement is able to determine at least one new biomarker based on a combination between at least these two OBPs.

A control device according to an aspect of the present disclosure includes: at least one memory configured to store instructions; and at least one processor configured to execute the instructions to: acquire an input image including an eye region that is a region of an eye part; estimate illuminance of the eye part from the acquired input image; and determine a light amount of illumination of visible light with which the eye part is irradiated in such a way that a pupil size of the eye part satisfies a size condition based on an illuminance size relationship that is a relationship between the illuminance and the pupil size.