Systems and methods are provided for measuring depth, position, and/or angle of a cannula in a medical drug delivery device. In particular, a drug delivery device having a cannula is positioned adjacent to tissue, a voltage pulse is provided to the cannula, a charge is measured at an electrode in the drug delivery device, and the depth of penetration of the cannula is determined based in part on the charge at the first electrode. Systems and methods described herein can be used to determine subcutaneous insertion depth in a wearable bolus injector. In some implementations, insertion depth determination is achieved through capacitive sensors which measure needle depth in a drug delivery device.

A wound dressing can include a substantially flexible substrate with a first, wound-facing side supporting a plurality of electronic components and a second side opposite the first side. The plurality of electronic components can include a light source, a resistor-capacitor (RC) network, and at least one switch electrically connected to the light source and to the RC network. The at least one switch can be configured to, in a first state, permit power to be supplied to the light source and, in a second state, prevent power being supplied to the light source.

In certain examples, methods and structures are directed to an apparatus having a plurality of stretchable leads, with each of the plurality of stretchable leads including an associated electrode which is to receive electrical signals generated in response to a subject-s heart and to pass the received electrical signals along a respective one of plurality of stretchable leads. The apparatus also includes a patch integrating the stretchable substrate with the plurality of stretchable leads and with the patch having an area for circuitry to reside for collecting the electrical signals passed along each of the plurality of stretchable leads, wherein each of the plurality of stretchable leads is to be on a subject side of the patch. In more particular examples, the circuitry is used to provide a multi-lead ECG based on the electrical signals.

Multi-layer contact patches, as well as related apparatus, kits, systems, and methods, enable improved allergen testing and diagnosis. Multi-layer contact patches include a shield layer releasably coupled to an adhesive layer. The adhesive layer at least partially defines and is fixably coupled to an allergen complex layer. The allergen complex layer defines a plurality of allergen complex cavities. At least a subset of the allergen complex cavities include an allergen complex positioned therein, each allergen complex comprising an absorbent matrix and an allergen.

A blood pressure (BP) measuring device including a PPG sensor, having one or more light sources and one or more light detectors; a computing unit, including a receiver for receiving PPG signals from the PPG sensor and a sampling circuit, for generating PPG signals samples of the PPG signals, where the device also includes a processor having BP calculation functionality, for processing the PPG signals samples into sequential BP values and a BP output unit, for outputting the calculated BP values, where the sampling circuit is adapted to sample at high sampling rate and provide BP values at a rate higher than 1 BP value per second, where the device may also include an electrogram sensor, having one or more electrodes for outputting tissue electrical activity values, the computing unit is connected to the electrogram sensor.

An apparatus adherable to a user's skin, such as a wearable medical device, is presented here. An embodiment of the apparatus includes a durable component having a periphery defining a footprint of the durable component, and a skin adhesive component coupled to the durable component to facilitate securing the durable component to the user's skin. The skin adhesive component includes a first region and a second region removably attached to the first region. The first region of the skin adhesive component resides completely within the footprint of the durable component. After removal of the second region of the skin adhesive component, the first region remains intact and protected underlying the durable component.

An injection sensing device (ISD) (e.g., wearable patch) is paired with an external device (e.g., a medication delivery pen and/or smart phone, iPad, computer) via wireless link or wireline connection. The ISD senses fluctuations in local skin temperature during an injection and provides to the external device captured data from the sensor relating to medicine delivery to a patient to ensure complete delivery and minimize MDD misuse or malfunction or inaccuracies in dosing. The ISD or external device can use captured data and corresponding time stamps to determine flow informatics such as flow rate, total dose delivered, and dose completion status. An LED on the ISD indicates delivery in progress and/or delivery completion.

A system for treating and/or monitoring a patient includes a patient physiological parameter monitoring patch and a companion device. The patient physiological parameter monitoring patch including an energy harvesting module, an energy storage module, a sensor module and a communication module. The energy harvesting module harvesting energy from one or more ambient sources, the energy being storable in the energy storage module and usable by one or more components of the patient physiological parameter monitoring patch. The sensor module senses one or more physiological parameters of the patient and the communication module can transmit the sensed data. The companion device can receive the sensed physiological parameters and can send the same to a remote device or store the same.

An analyte sensor system may include a first communication circuit configured to transmit a wireless signal in a first communication mode and a second communication mode, and a processor, wherein the processor determines whether a first condition is satisfied, the first condition relating to the sensor signal or to communication by the first communication circuit, and shifts the system to a second communication mode responsive to the first condition being satisfied.

Disclose is a dry adhesive patch comprising: a plurality of embossed pillars formed on a substrate; a hemi-spherical adsorbing cup defining a top portion of each pillar, wherein a hemi-spherical hole is defined in a top portion of the adsorbing cup and is exposed to an outside; and an annular extension extending radially from an outer perimeter of a distal end of each adsorbing cup.