There is provided a method of forming a thin film-based microfluidic electronic device. The method includes: providing a first elastomeric thin film layer on a substrate; depositing a first elastomer on the first elastomeric thin film by direct ink writing to form an elastomeric structure configured to define a microfluidic channel on the first elastomeric thin film layer; providing a second elastomeric thin film layer over the elastomeric structure to cover the microfluidic channel; providing a sacrificial layer on the second elastomeric thin film; depositing liquid metal into the microfluidic channel to form a conductor in the microfluidic channel; and electrically connecting the conductor to an electronic component. The thin film-based microfluidic electronic device is a tissue or skin adhesive sensor including a skin adhesive acoustic device.

An apparatus for estimating body temperature of an object is provided. The apparatus for estimating body temperature includes: a sensor configured to obtain spectra through a plurality of light paths of an object; and a processor configured to obtain a temperature slope between temperatures corresponding to the plurality of light paths based on the spectra of the plurality of light paths and a reference spectrum measured at a reference temperature, and estimate the body temperature of the object based on the temperature slope.

A wearable sensing device (100) for sensing one or more physiological signals of a subject, comprising: a sensor unit (200), including a housing, a connection receptacle (210) and electronic circuitry configured for acquiring one or more physiological signals received via the connection receptacle; a patch unit (300), including a connection plug (310) connected via conductive tracks (341) to a plurality of electrodes (342) configured for sensing the one or more physiological signals. The connection plug (310) is configured for being connectable with the connection receptacle (210) such that the one or more physiological signals sensed by the electrodes (342) are transmitted to the electronic circuitry of the sensor unit (200). The patch unit (300) comprises at least one top layer (380) and at least one bottom layer (360, 330), each including an adhesive material, such that the at least one top layer (380) is configured to be attachable to a surface of the housing and the at least one bottom layer (360, 330) is configured to be attachable to the skin of the subject.

A flexible, multi-layered device for automatically sensing sweat biomarkers, storing and transmitting sensed data via wireless network to a computing device having software applications operable thereon for receiving and analyzing the sensed data. The device is functional in extreme conditions, including extremely hot temperatures, extremely cold temperatures, high salinity, high altitude, extreme pHs, and/or extreme pressures.

The present invention presents a method of fabrication for a physiological sensor with electronic, electrochemical, and chemical components. The fabrication method comprises steps for manufacturing an apparatus comprising at least one electrochemical sensor, a microcontroller, and a transceiver. The fabrication process includes the steps of substrate fabrication, circuit fabrication, pick and place, reflow soldering, electrode fabrication, membrane fabrication, sealing and curing, layer bonding, and dressing. The physiological sensor is operable to analyze biological fluids such as sweat.

Provided is a wearable patch that can reliably interrupt the power supply from the cell after use and can be disposed of as it is. Moreover, provided is a sheet-type cell that can reliably interrupt the power supply after use and can be disposed of safely. The wearable patch is worn on the body and includes a functional element, a drive circuit unit that operates the functional element, and a cell as a power source. A cutting facilitating member is formed to allow a predetermined portion of the wearable patch to be cut with a force of 200 N or less so that the power supply from the cell to the drive circuit unit is interrupted.

Wearable ergonomics improvement systems and related methods are disclosed. An example ergonomics improvement system includes a membrane including a first frame having a plurality of first cutouts defining a first pattern. The system includes a sensor coupled to the membrane and includes a second frame having a plurality of second cutouts defining a second pattern. The first pattern is complementary to the second pattern.

A base plate and/or a sensor assembly part for an ostomy appliance is disclosed, the base plate and/or the sensor assembly part comprising a first adhesive layer with a proximal side configured for attachment of the base plate and/or the sensor assembly part to the skin surface of a user, the first adhesive layer having a stomal opening with a center point; and a plurality of electrodes including a ground electrode, a first electrode, and a second electrode, the ground electrode comprising a ground connection part, the first electrode comprising a first connection part, and the second electrode comprising a second connection part; wherein the ground electrode forms a ground for the first electrode and the second electrode.

The present invention provides a bio-electrode composition including a silicone bonded to a sulfonamide salt, wherein the sulfonamide salt is shown by the following general formula (1): ##STR00001##
wherein R.sup.1 represents a linear, branched, or cyclic alkylene group having 1 to 20 carbon atoms optionally having an aromatic group, an ether group, or an ester group, or an arylene group having 6 to 10 carbon atoms; Rf represents a linear, branched, or cyclic alkyl group having 1 to 4 carbon atoms and containing at least one fluorine atom; M.sup.+ is an ion selected from a lithium ion, a sodium ion, a potassium ion, and a silver ion. This can form a living body contact layer for a bio-electrode that is excellent in electric conductivity and biocompatibility, light-weight, manufacturable at low cost, and free from large lowering of the electric conductivity even though it is wetted with water or dried.

Systems, devices, and methods for interfacing with biological tissue are described herein. An example electrode patch as described herein includes a flexible substrate and an electrode array arranged on the flexible substrate. The electrode array includes a plurality of electrodes, where each of the plurality of electrodes is formed of a hydrogel. Additionally, each of the plurality of electrodes defines a raised geometry. Additionally, an example system includes the electrode patch, which is configured to interface with a subject's skin, and an electronics module operably coupled to the electrode array.