A transdermal patch measures a gaseous concentration based on transcutaneous diffusion through an epidermal surface of a patient. The patch employs an indicator responsive to a gaseous presence for emitting light having an intensity and lifetime (duration) based on the gaseous presence. An optical receptor is in communication with logic for receiving the intensity of emitted light and computing a gaseous concentration based on the received intensity and lifetime (duration). A wireless transmitter conveys the results to a base station or monitoring counterpart for untethered patient monitoring. Low power demands and circuit footprint are amenable to a wearable device such as a patch for continuous use.

The present invention is intended to provide a gel sheet having a formulation providing an adhesive force on the skin side suitable for the skin (i.e., a gel having a low adhesive force and being able to withstand a tip pressure of a terminal and the like), and concurrently having a sufficient adhesive force against an electrode element on the side opposite to the skin side. The present invention is a gel sheet having a laminated structure of a layer A and a layer B, characterized in that the storage elastic modulus of the layer A at 23° C. and 10 Hz is 12,000 to 40,000 Pa, and the storage elastic modulus of the layer B at 23° C. and 10 Hz is 2,000 to 10,000 Pa.

A pressure sensor system is provided. In another aspect, a wireless intraocular pressure sensor includes a deformable or stretchable inductor. A further aspect of an intraocular pressure sensing system includes a deformable inductor sized to contact an eye. Another aspect provides an organ pressure sending system including a passive inductor with a wavy, serpentine or undulating shape.

Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.

Numerous aspects of communication devices, methods, and systems are described in this application. One aspect is an apparatus comprising an energy generator comprising a plurality of generator elements operable to output a plurality of different energy types in a signal direction toward the skin. Each generator element of the plurality of generator elements may be independently operable, when the energy generator is positioned relative to skin, to communicate with different nerves associated with the skin by outputting a different portion of an energy signal in the signal direction toward the skin with one energy type of the plurality of different energy types.

A patch and sensor assembly has a biosensor housed in a reusable portion that connects to a mapping and localization system (MLS) via biosensor wires. A disposable portion has an electrode layer through which signals are transmitted to the MLS via ACL wires. The biosensor and ACL wires extend through a single cable exiting the reusable portion. The disposable portion includes an adhesive layer for adhering the electrode layer to a patient, on the electrode layer, and an engagement element for detachably receiving at least a portion of the housing of the reusable portion. The reusable portion includes a housing in which the biosensor has biosensor wires that exit the reusable portion. The housing is also adapted to carry and/or provide support to an ACL contact member responsive to the electrode layer of the disposable portion, and ACL wires that exit the reusable portion.

An adhesive device may include a first adhesive surface configured to be adhered to skin of a user, and a second adhesive surface opposite the first adhesive surface and configured to be adhered to a medical device. The adhesive device may also include an intermediate region between the first adhesive surface and the second adhesive surface, where the intermediate region includes a detector compound embedded in the intermediate region configured to change based on interaction of the detector compound with a target molecule.

A modular wearable health monitor having a substantially flexible attachment means connected to a housing comprising a power source and at least one processor through a relatively rigid and narrow spine disposed substantially centrally thereon having a variety of clinical and non-clinical uses that provides more comfortable and durable attachment of biometric sensors to a user by allowing the attachment means to contour to the user's body without the housing also being forced to do so along its entire width.

A sensor cover includes a cover film having an upper cover film and a lower cover film that are joined to each other at least at respective one sides thereof, and the cover film is shaped like a bag and configured to accommodate a temperature sensor when in use. The sensor cover also includes a self-adhesive member that has adhesiveness and is disposed on an outside surface of the lower cover film. The sensor cover further includes a sensor mounting member that is disposed on an inside surface of the lower cover film and configured to attach the temperature sensor closely to the lower cover film. The sensor cover further includes a sealing member that closes and seals an edge portion of an opening of the cover film.

A wearable device according to an embodiment includes a detection unit, a first layer, a second layer, and a third layer. The detection unit detects the living body information. The first layer is flexible and disposed in a first direction relative to the detection unit and includes a conductor electrically connected to the detection unit. The second layer is disposed in the first direction relative to the first layer and is harder than the first layer. The third layer is disposed in the first direction relative to the second layer and includes an electronic component electrically connected to the conductor.