A system for measuring cardiovascular data includes an elongate member having a channel, a first expandable member carried by the elongate member and movable between a collapsed state and an expanded state by adjustment initiated externally of a subject, a first sensor disposed on a surface of the elongate member, second and third sensors disposed on a surface of the first expandable, a first optical sensor located at a first location in relation to the distal end of the elongate member and configured for obtaining photoplethsmographic data, and wherein the first expandable member in its expanded state is configured to interface with the subject's larynx for delivery of at least oxygen gas into the respiratory system of the subject, and the second and third sensors are configured to contact tissue in proximity to the larynx when the first expandable member is in its expanded state.

Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods include evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.

An apparatus includes a catheter, a sensor, a first pair of wire segments, an artifact reduction feature, and a correction module. The sensor is positioned at a distal end of the catheter and is configured to generate a sensor signal. The first pair of wire segments is coupled with the sensor and extends along the length of the catheter. The artifact reduction feature is positioned proximate to the sensor and includes a second pair of wire segments. The correction module is configured to subtract motion-induced artifacts from signals received from the first pair of wire segments, based on motion-induced artifacts from signals received from the second pair of wire segments, to thereby provide a corrected sensor signal.

A system and method for assessing contact between a medical device and tissue may comprise an electronic control unit (ECU) configured to be coupled to a medical device, the medical device comprising a first electrode and a second electrode. The ECU may be further configured to select the first electrode as an electrical source and the second electrode as an electrical sink, to cause an electrical signal to be driven between the source and sink, to detect respective electric potentials on the first electrode and the second electrode while the electrical signal is driven, and to determine an impedance respective of one of the first electrode and the second electrode according to both of the respective electric potentials.

A catheter may be adapted to map a chamber of the heart. The catheter may include a magnetic and/or ultrasound sensor for navigation. The body of the catheter may be pliable and configured to form a predetermined shape upon exiting a catheter sheath. Upon exiting the catheter sheath, the catheter body may be configured to form one or more loops, and the loops may be non-overlapping loops. In some examples, the non-overlapping loops may be concentric loops. Alternatively, the catheter body may be configured to form one or more splines. The catheter body may include an embedded electrode assembly. The electrodes of the electrode assembly may be may be arranged in one or more rows and configured to detect a wave front. The electrode assembly may also be configured to generate and activation sequence and determine a direction of an activation source. The electrode assembly may also be configured to determine the type of activation source, for example a rotational activation source, a focal activation source, and a single-wide activation source.

An electrophysiology catheter has a micro capacitive tactile sensor provided in the distal section. The distal section may include a tip electrode, a ring electrode and/or a balloon catheter adapted for tissue contact. The capacitive force sensor is configured to exhibit a change in capacitance with tissue contact wherein the force applied with tissue contact is measured and reliably calibrated in assessing and determining the applied force. The capacitive force sensor has a first plate affixed to a tissue contact portion of the catheter, a second plate configured for contact with the tissue, and an elastically compressible dielectric between the first and second plates, wherein the force sensor has a first capacitance when the first and second plates are separated by a first distance, and the force sensor has a second capacitance when the first and second plates are separated by a second different from the first distance.

Dual sensor system for continuous blood pressure monitoring during transcatheter heart valve therapies (TVT), such as transcatheter aortic valve replacement (TAVR) or transcatheter mitral valve replacement (TMVR), comprises a controller, a support guidewire for TVT containing a first Fabry-Pérot (FP) optical pressure sensor near its distal end, and a pigtail catheter for delivery of contrast medium containing a second FP optical pressure sensor near its distal end. For example, for TAVR, the support guidewire is positioned to place the first optical pressure sensor within the left ventricle (LV) for monitoring LV pressure, the pigtail catheter is positioned in the aorta to place the second optical pressure sensor in the ascending aorta for direct measurement of pressure in the aorta, downstream of the aortic valve, enabling continuous monitoring of blood pressure at both sensor locations during TAVR. The controller may be configured to interface with standard patient monitoring systems.

The present invention relates to an ablation equipment (100) to treat target regions of tissue (41) in organs (44), comprising an ablation catheter (1) and a single power source (4);

said ablation catheter (1) comprising: a catheter elongated shaft (13) comprising at least an elongated shaft distal portion (17); said catheter elongated shaft (13) comprising a flexible body (207) to navigate through body vessels (208);
said ablation catheter (1) further comprising a shaft ablation assembly (20) disposed at said elongated shaft distal portion (17); said shaft ablation assembly (2) comprising at least a plurality of electrodes (127, 113 or 114) fixedly disposed at said elongated shaft distal portion (17);
all electrodes of said at least a plurality (127, 113 or 114) being electrically powered by said single power source (4) through an electric signal (S) to deliver both non-thermal energy for treating the tissue (41) and thermal energy for ablating the tissue (41);
wherein
said single power source (4), when requested, changes continuously said electric signal (S) in order to power the said least a plurality of electrodes (127, 113 or 114) to deliver from a non-thermal energy to a thermal energy, and vice versa, or to deliver at the same time a combination of thermal energy and non-thermal energy.

A display control device includes processing circuitry configured to: obtain an intracardiac electrocardiogram of a subject; generate visualization data representing an excitation state of a myocardium based on the intracardiac electrocardiogram; determine a type of excitation dynamics of the myocardium based on the visualization data; and display, on a stereoscopic image of a heart of the subject, a site from which the intracardiac electrocardiogram is obtained with a color in accordance with a ratio of the determined type of the excitation dynamics.

An electrophysiology catheter has a micro capacitive tactile sensor provided in the distal section. The distal section may include a tip electrode, a ring electrode and/or a balloon catheter adapted for tissue contact. The capacitive force sensor is configured to exhibit a change in capacitance with tissue contact wherein the force applied with tissue contact is measured and reliably calibrated in assessing and determining the applied force. The capacitive force sensor has a first plate affixed to a tissue contact portion of the catheter, a second plate configured for contact with the tissue, and an elastically compressible dielectric between the first and second plates, wherein the force sensor has a first capacitance when the first and second plates are separated by a first distance, and the force sensor has a second capacitance when the first and second plates are separated by a second different from the first distance.