In some embodiments, a reconstitution or medicinal fluid delivery device includes a transfer engine including two fluidly connected spikes, each configured to pierce a container. A check valve may be disposed between the two spikes to allow unidirectional flow from one container to the other. Physical access to a fluid outlet may be obstructed by a housing until the reconstitution or medicinal fluid delivery device is actuated, whereupon physical access to the fluid outlet is permitted. The reconstitution or medicinal fluid delivery device may be placed on a flat surface and actuated with force applied in a single direction toward the flat surface.

A method for filling containers with fresh blood components, comprising the following steps of: a) providing a piece of equipment (1) defining a transit channel (3) having at least a first gap (3a) associated with a bag (5) or the like containing a fresh blood component, at least a second gap (3b) connected to a plurality of containers (6) to be filled, and at least a third gap (3c) connected to pumping means (12); b) isolating the first gap (3a) from the second gap (3b) and placing the latter in communication with the third gap (3c); c) suctioning the air contained in the containers (6) to be filled by means of the pumping means (12) so as to define a vacuum inside them; d) placing the first gap (3a) in communication with the second gap (3b), the containers (6) suctioning the contents of the bag (5) by effect of the vacuum defined inside them; and where the channel (3) has at least a fourth gap (3d) associated with an empty syringe (4) or the like, and by the fact that it comprises, after step d), the following steps of: e) isolating the first gap (3a) from the second gap (3b) and placing the first gap itself in communication with the fourth gap (3d); f) taking at least a part of the contents of the bag (5) by means of the syringe (4); g) isolating the fourth gap (3d) from the first gap (3a) and placing the fourth gap itself in communication with the second gap (3b); h) sending the contents taken with the syringe (4) into the containers (6).

Fluid transfer systems are disclosed that can be configured to transfer precise amounts of fluid from a source container to a target container. The fluid transfer system can have multiple fluid transfer stations for transferring fluids into multiple target containers or for combining different types of fluids into a single target container to form a mixture. The fluid transfer system can include a pump and a destination sensor, such as a weight sensor. The fluid transfer system can be configured to flush remaining fluid out of a connector to reduce waste, using air or a flushing fluid.

A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.

A flexible multi-chamber bag for storing and reconstituting parenteral nutrition solutions is disclosed. The flexible multi-chamber bag comprises a first peelably sealing wall and a second peelably sealing wall between the two polymer films extending from the top edge to the bottom edge and separating the first bag into a first chamber between the first peelably sealing wall and the second peelably sealing wall, a first space between the left edge and the first peelably sealing wall, a second space between the second peelably sealing wall and the right edge; a third peelably sealing wall extending from the left edge to the first peelably sealing wall to separate the first space to form a third chamber and a fourth chamber; and a fourth peelably sealing wall extending from the right edge to the second peelably sealing wall to separate the second space to form a second chamber and a fifth chamber.

A liquid transfer device includes a monolithic trifurcated connector body defining a barrel at a first end thereof, a single IV spike at a second end thereof and a vial adapter lumen at a third end thereof. An IV port is connected to the barrel. The single IV spike has a first IV spike lumen fluidly connected at a proximal end thereof with only the vial adapter lumen via the trifurcated connector body and a second IV spike lumen fluidly connected at a proximal end thereof with only the IV port via the trifurcated connector body, thereby separating fluid communication between the vial adapter and the single IV spike from fluid communication between the IV port and the single IV spike.

A system for preparing an injection includes a first container with a first cavity and a rigid outer wall and two ends, a movable stopper being provided on one side of the first cavity, which sealingly closes this cavity and is displaceable inside the first container and comprising a second container, which encloses a second cavity, one container comprising a first substance, and the other container comprising a second substance. The second container comprises an at least regionally elastic wall and in this way has a variable volume. The second container is designed such that a pressure can be built inside the second container by way of the at least regionally elastic wall. The second container is a tube.

In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.

A liquid transfer device includes a monolithic trifurcated connector body defining a barrel at a first end thereof, a single IV spike at a second end thereof and a vial adapter lumen at a third end thereof. An IV port is connected to the barrel. The single IV spike has a first IV spike lumen fluidly connected at a proximal end thereof with only the vial adapter lumen via the trifurcated connector body and a second IV spike lumen fluidly connected at a proximal end thereof with only the IV port via the trifurcated connector body, thereby separating fluid communication between the vial adapter and the single IV spike from fluid communication between the IV port and the single IV spike.

Disclosed is a transfer device for use in reconstituting dry drugs and for diluting liquid drugs in drug containers. The transfer device includes a multi-port manifold and a connector suitable to be attached to a drug container, a first conduit to transfer a liquid entering an inlet port of the manifold through the connector and into the drug container, and a second conduit to transfer a gaseous fluid through the connector to an outlet port of the manifold. Also disclosed is a closed liquid transfer system which includes the transfer device, a tube connectable to the inlet port for transporting a liquid to the transfer device, a tube connectable to the outlet port for transporting the gaseous fluid away from the transfer device, and a gas collection container to collect the gaseous fluid in the gas transporting tube.