The invention relates to an adapter (1) for a transfer device (20) for a fluid, for the connection of a container (17) containing the fluid, wherein the container (17) is closed by a pierceable closure element (18), and the adapter (1) has an attachment (4) which can be fitted sealingly, in an attachment direction, onto a container mouth closed by the closure element. A penetration element (6) is mounted on the attachment (4) in such a way that the penetration element (6) is movable, with the aid of guide means, between a rest position (R) and a withdrawal position (E), wherein the penetration element (6) has a hollow needle (9) with which the closure element (18) can be pierced in the withdrawal position (E). The adapter (1) has a connector stub (3) with a coupling for the fluid-tight connection of a further adapter (1′), and a transfer channel (10) runs from a mouth on the connector stub (3) to a mouth on the hollow needle (9), such that the mouth of the transfer channel (10) on the connector stub (3) communicates with an interior of the connected container (17) in the withdrawal position (E) of the penetration element (6). The invention is characterized in that the connector stub (3) is arranged transversely, in particular substantially perpendicularly, with respect to the attachment direction (H), preferably on the penetration element (6).

The present relates to a component mixing device comprising a central unit (10) and a disposable cartridge, said central unit (10) comprising a control unit, a plurality of vial positioning elements (13) and a cavity 14 for receiving said disposable cartridge, and said disposable cartridge (20) comprising a tubing circuitry adapted to put the components housed in said plurality of vials into communication for mixing, characterized in that the mixing device is adapted to put each vial into communication with each other through said tubing circuitry of said disposable cartridge (20) and mixing said components through an compressed air mechanism (12) located in said central unit (10) and controlled by said control unit.

A method for the filling of containers with autologous fresh blood components, comprising the following phases of: a) providing an equipment (1) defining a transit channel (3) having at least a first gap (3a) associated with an empty syringe (4) or the like, at least a second gap (3b) associated with a bag (5) or the like containing an autologous fresh blood component and at least a third gap (3c) connected to a plurality of containers (6) to be filled; b) insulating the second gap (3b) from the third gap (3c) and placing in communication the first gap (3a) with the third gap (3c); c) suctioning the air contained in the containers (6) to be filled by means of said syringe (4) so as to define a vacuum inside them; d) insulating the first gap (3a) from the third gap (3c) and placing in communication the latter with the second gap (3b), the containers suctioning the contents of the bag (5) due to the effect of the vacuum defined inside them.

An assembly for mixing drug components includes a housing to at least partially hold a first drug component container and a second drug component container. The assembly also includes a transfer member having first and second ends to fluidly couple the respective first and second drug component containers. The assembly further includes a pressure member to fluidly couple the first drug component container to a pressure generation chamber. In addition, the assembly includes an energy storage member to generate pressure in the pressure generation chamber to transfer a fluid from the first drug component container into the second drug component container. Moreover, the assembly includes an exit member to fluidly couple the second drug component container to an exterior of the assembly.

Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needleless fluid port and a needleless vent port for fluid coupling to a vial via a vial puck. The vial puck includes corresponding needleless fluid and vent ports and a cannula. The cannula is extendible, by insertion of a protrusion on the cartridge into a shaft of the vial puck, into the vial to couple the vial to the needleless fluid and vent ports.

A liquid transfer device is provided having a trifurcated body that includes a vial adapter at a first end configured to telescopically mount on the crown of an IV bottle to puncture a stopper in the crown with a cannula, an IV port extending from an opposing second end of the trifurcated body, and a needleless self-sealing port extending from a third end of the trifurcated body and configured to couple with the male connector of an additive transfer device. Methods of using the liquid transfer device with an IV bottle, additive transfer device, and an infusion set to prepare an infusion liquid for administration to a patient are also provided.

Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needleless fluid port and a needleless vent port for fluid coupling to a vial via a vial puck. The vial puck includes corresponding needleless fluid and vent ports and a cannula. The cannula is extendible, by insertion of a protrusion on the cartridge into a shaft of the vial puck, into the vial to couple the vial to the needleless fluid and vent ports.

The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. In one example, the system comprises a container for holding the therapeutic agent, and a pressure source having pressurized fluid, wherein the pressure source is in selective fluid communication with at least a portion of the container. A catheter is placed in fluid communication with the container, and has a lumen sized for delivery of the therapeutic agent to a target site. A housing is configured to securely retain the container. The system further comprises a camera having a camera head coupled to the catheter, wherein the camera provides a visual image of the target site during delivery of the therapeutic agent.

A reconstitution device includes: a piercing member having a first end and a second end, the first end of the piercing member configured to engage an administration port; a delivery member having a first end and a second end, the first end of the delivery member configured to engage a delivery site; a collar configured to engage a vial; and a cap extending from the collar and holding the piercing member and the delivery member such that the second end of the piercing member and the second end of the delivery member are disposed within the cylindrical collar.

Disclosed is a transfer device for use in reconstituting dry drugs and for diluting liquid drugs in drug containers. The transfer device includes a multi-port manifold and a connector suitable to be attached to a drug container, a first conduit to transfer a liquid entering an inlet port of the manifold through the connector and into the drug container, and a second conduit to transfer a gaseous fluid through the connector to an outlet port of the manifold. Also disclosed is a closed liquid transfer system which includes the transfer device, a tube connectable to the inlet port for transporting a liquid to the transfer device, a tube connectable to the outlet port for transporting the gaseous fluid away from the transfer device, and a gas collection container to collect the gaseous fluid in the gas transporting tube.