Disclosed are stable, non-irritating, skin treatment active agents containing formulations and delivery systems for topical application to the skin. The disclosed topical formulations and delivery systems provide controlled, gentle release of the active agents into the skin for the treatment of amenable skin conditions as well as for improvement of aesthetic skin properties. Also provided are methods for the formulation, manufacture and use of the disclosed formulations and delivery systems.

The present invention concerns a process for preparing a polyphenol-rich extract of dry plant biomass, in particular parts of vines, the extract obtained and its use for antifungal applications, in particular for the prevention and treatment of fungal infections on fruits and plants after harvest, but also for applications related to its antibacterial and antioxidant properties.

The invention relates to a personal care product for alleviating skin dryness, including facial skin dryness, body dryness, and breast skin dryness and for use as a massage oil. Embodiments of the personal care product include a formulation including cocoa butter, kokum butter, shea olein, and hyaluronic acid and/or cannabis oil. The personal care product may also include other plant-based glycerides, natural hormones, herbal roots and oils, amino acids, dietary supplements. The personal care product is substantially free of added water, alcohol, synthetic chemical, anti-microbial, and synthetic hormone.

An external skin preparation is described, and contains an oil-soluble ultraviolet absorber, 0.5% by mass or more and 20% by mass or less of an oil gelling agent, and 50% by mass or more of a non-aqueous volatile component. The external skin preparation is unlikely to drip upon application, provides an impression from use of less oiliness and less tightness, is likely to have a uniform distribution of the oil-soluble ultraviolet absorber on the skin surface after application to the skin, and has an excellent ultraviolet protection effect.

The invention provides certain compositions and methods for dental care, which alone or in combination with other dental technologies can help to achieve better outcomes in terms of the enhancement of oral hygiene as regards to preservation of the healthy oral and/or dental flora, minimization or a reduction of the proportion of harmful bacteria, and further facilitate the enhancement of a more healthy appearance of teeth and gums. The oral formulation for improving oral and/or dental hygiene, and/or for enhancing the healthy appearance of teeth and gums, comprises Dead Sea salt and at least one synthetic, semi-synthetic or natural cannabinoid, a precursor, a derivative, or any combination thereof, or an extract of a Cannabis plant.

The present invention is directed to a personal care composition containing resorcinols. An effective way to improve the color stability of compositions comprising resorcinols is desired. It has been found that alkylresorcinols and retinoids in combination with a compatible oil and specific ratios of antioxidants provide for improved color stability of the resorcinols. The invention thus relates to a composition comprising a synergistic combination of butylated hydroxytoluene and dilauryl thiodipropionate with alkylresorcinols and retinoids.

A complex of curcumin with a polyphenolic macrocyclic host is disclosed. The macrocyclic host is a resorcin[4]arene. In one approach, the polyphenolic macrocyclic host is calix[8]arene. In another approach, the polyphenolic macrocyclic host is tert-butylcalix[8]arene.

Aspidin BB derivatives, compositions containing them, and methods of making and using them.

Disclosed is a powder composition consisting essentially of Magnolia officinalis bark extract comprising magnolol and honokiol, tocopherol or tocopherol acetate, lecithin, at least one gum, and optionally water, wherein the composition is in powdered form.

The present invention relates to new odorous acetals which are useful as fragrance or flavor materials in particular in providing vanilla and spicy notes with a natural impression resembling vanilla absolute.