The present disclosure relates to anhydrous hydrogels useful as mucoadhesive (oral compositions) or as topical agents and may be used to deliver an active agent such as active pharmaceutical agents (API's), coagulants, fragrances, flavors, and other actives and excipients.

Provided is a nanoemulsion which has stability and to which preservative efficacy is imparted, in a bacterial contamination environment. This object is attained by a nanoemulsion which has an average particle diameter of 30 nm or less, has a particle size distribution index of 0.14 or less, does not contain particles of 100 nm or more, and contains, as a preservative, at least one selected from an organic acid (salt) and a biguanide-based compound.

An oral care product comprising at least one of phytomenadione (vitamin K.sub.1), menaquinone (vitamin K.sub.2), vitamin C, selenium, ubiquinone (Coenzyme Q.sub.10), Astragalus, Ginseng, Schisandra, adaptogenic herbs, cannabidiol, or the like. An oral care product directed toward rebalancing micro-bacterial homeostasis in the mouth, or establishing and maintaining a healthy oral microbiome.

The present invention is related to an aqueous conditioning composition for hair comprising at least one alkyl ester/amido alkyl amine or alkyl ester/amido alkyl quaternary amine and an aqueous emulsion of divinyldimethicone/dimethicone copolymer. In particular, a conditioning composition for hair comprising at least one compound according to general structure
R.sub.1-A-R.sub.2B
wherein R.sub.1 is a saturated or unsaturated, straight or branched alkyl group with 8 to 24 C atoms, R.sub.2 is a straight or branched alkyl group with 1 to 4 C atoms, A is a group selected from O, ##STR00001##
and B is selected from ##STR00002##
wherein R.sub.3 and R.sub.4 are the same or different is H or an alkyl with 1 to 4 C atoms, hydroxyl alkyl with 1 to 4 C atoms and di hydroxyl alkyl with 2 to 4 C atoms, R.sub.5, and R.sub.6 are the same or different, an alkyl with 1 to 4 C atoms, hydroxyl alkyl with 1 to 4 C atoms and di hydroxyl alkyl with 2 to 4 C atoms, R.sub.7 is an alkyl with 1 to 4 C atoms, hydroxyl alkyl with 1 to 4 C atoms or di hydroxyl alkyl with 2 to 4 C atoms and
R.sub.2-A-R.sub.1
wherein R.sub.1, A and R.sub.2 have the above meaning and X is chloride, bromide, methosulfate and an aqueous emulsion of divinyldimethicone/dimethicone copolymer with an internal phase viscosity of more than 110.sup.8 mm.sup.2/s measured at 0.01 Hz and at approximately 25 C.

The invention relates to a composition comprising melatonin, a metabolite or derivative thereof and coenzyme Q10 and to use thereof for the production of a pharmaceutical or cosmetic composition for the treatment of the skin, said composition potentiating the movement of both molecules into the mitochondrion and facilitating percutaneous absorption, in which both the melatonin and the CoQ10 can reach all of the strata of the skin.

The present invention relates to a composition comprising at least one first compound of the formula (I), or a polymer of the first compound and at least one second compound of formula (I), of the following formula (II) or of the following formula (III), the second compound of formula (I) being different from the first compound of formula (I).

An essential oil composition, at least including a silicone mixture and a vegetable oil mixture, wherein the silicone mixture includes a first polysiloxane and a second polysiloxane, the vegetable oil mixture includes an emollient formed by at least three vegetable oils, and the vegetable oil mixture is added dropwise to the silicone mixture while the silicone mixture is being stirred. The essential oil composition is transparent and non-turbid in appearance, and has a refreshing effect after being applied to skin surface. After washing hands, water droplets would not be present on the skin surface which has the composition applied thereto, and therefore would not feel sticky or greasy. The present invention further provides a method for manufacturing an essential oil composition, and a use of an essential oil composition in preparation of a cosmetic product for improving skin conditions, thereby relieve the red and swollen appearance of dermatitis.

Oral care compositions with an anticaries or anticavity effect. Oral care compositions that have an extract from a species in the Humulus family and an anticaries drug, such as a fluoride ion source. Oral care compositions have fluoride and hops beta acid, such as from an extract from Humulus lupulus. Oral care compositions have a fluoride ion source and a hops beta acid derived from an extract of Humulus lupulus.

Embodiments described herein include semi-permanent inks (e.g., semi-permanent inks contains genipin, a genipin derivative, lawsone, a lawsone derivative, or combinations thereof); semi-permanent ink applicators; transfer mediums; silicone adhesives; and silicone mediums and kits containing two or more thereof. Some embodiments describe methods for applying an ink to skin as well as methods for increasing the darkness of a semi-permanent tattoo and/or increasing the longevity of a semi-permanent tattoo.

A method is provided to treat a subject in need of treatment for erythema, including facial erythema from any one of acne, rosacea, photoaging, heat/burns, heat from laser treatments, and/or injury scars that are in a red stage. The method includes topically administering to the subject in need thereof a composition having a therapeutically effective amount of lapachol and one or more acceptable excipients. The therapeutically effective amount correlates to the composition having approximately to 0.25% of lapachol by volume, and the administration of the composition being an application to an area affected by erythema twice per day.