A61K8/4966

Fused heterotricyclic organic compounds, pharmaceutical compositions, and medical uses thereof
11382916 · 2022-07-12 · ·

The invention provides fused heterocyclic organic compounds such as dihydropyrazolopyridotriazinones, compositions containing such compounds, medical kits, and methods for using such compounds and compositions for body contouring and/or reduction of fat in a subject.

NOVEL COSMETIC AND DERMATOLOGICAL USES OF AN EXTRACT OF CISTUS MONSPELIENSIS

Novel cosmetic and dermatological uses of an extract of Cistus monspeliensis The invention relates to the non-therapeutic cosmetic use of an extract of Cistus monspeliensis for increasing and/or maintaining tissue homeostasis in the skin and/or the mucous membranes and/or the skin appendages, by increasing and/or maintaining the barrier function and/or cell differentiation in the skin and/or the mucous membranes and/or the skin appendages. Another subject relates to a non-therapeutic cosmetic care process notably comprising the topical application of the extract of C. monspeliensis or of a cosmetic composition comprising same. Yet another subject relates to the extract of C. monspeliensis, for its use for preventing and/or treating diseases induced by a decrease in the gene and/or protein expression of ECM1, advantageously lichen sclerosus or lipoid proteinosis, and/or for preventing and/or treating scars.

CORE-SHELL PCM MICROCAPSULE HAVING AUTOMATIC TEMPERATURE CONTROL FUNCTION AND COOLING COSMETIC COMPOSITION FOR EXTERNAL SKIN INCLUDING THE SAME

Provided are preparation of a PCM microcapsule in the form of a core-shell having an excellent heat absorption function by using a temperature-controllable phase change material (PCM) as a core material and a biodegradable polymer material as a shell material, and a cooling cosmetic composition for external skin capable of exhibiting a prevention effect of thermal aging using the same. The core-shell PCM microcapsule having an automatic temperature control function according to the present invention is prepared by dissolving a shell material and a single or mixed PCM in a solvent to produce an oil phase polymer solution, dissolving an aqueous polymer to produce an external continuous phase, emulsifying the oil phase polymer solution and the external continuous phase, and removing the external continuous phase and the solvent and carrying out drying.

Singlet oxygen scavenger

A singlet oxygen scavenger includes, as an active component, hexyl diethyl amino hydroxy benzoyl benzoate, 1-(4-methoxy phenyl)-3-(4-tert-butyl phenyl)-1, 3-propanedione, terephthalylidene-3, 3′-dicamphor-10, 10′-disulfonate, 2-ethyl hexyl 4-methoxy cinnamate, or 2-ethyl hexyl 2-cyano-3, 3-diphenyl acrylate; or 2-phenyl benzimidazole-5-sulfonic acid, 4, 4′, 4″-[(1, 3, 5-triazine-2, 4, 6-triyl) tris (imino)] trisbenzoic acid tris (2-ethyl hexyl), octyl salicylate, or 3, 3, 5-trimethyl cyclohexyl salicylate; or 2-hydroxy-4-methoxy-5-(sodiooxysulfonyl) benzophenone, drometrizol trisiloxane, 2-hydroxy-4-methoxy benzophenone, or 4-methyl benzylidene camphor.

Cosmetic

A cosmetic including at least one cyclic silicone represented by formula (1), and having a boiling point of 205 to 255° C. and a viscosity of less than 5 mm.sup.2/s (25° C.). This cosmetic has a light touch, a good spread, and excellent water repellency, forms a uniform cosmetic film, can achieve a feeling of use without a strong oily feeling, and has stability over time and cosmetic persistence when a variety of oil such as a silicone, hydrocarbon oil, and ester, an organic ultraviolet absorber, or an oily component being solid at 25° C. is mixed. ##STR00001## (Wherein R.sup.1 is a monovalent hydrocarbon group having 2 or 3 carbon atoms, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are each independently a monovalent hydrocarbon group having 1 to 3 carbon atoms, “a” is a positive number satisfying 0<a<4, and “b” and “c” are each independently a number of 0 to 3, provided that (a+b+c)≤4.)

METHOD FOR OBTAINING BIOACTIVE INGREDIENTS, USE OF SUBCRITICAL-WATER EXTRACTION PROCESS, BIOACTIVE INGREDIENT, USE OF BIOACTIVE INGREDIENT AND COSMETIC COMPOSITION

The present invention relates to a method for obtaining single-use bioactive ingredients using a specific extraction process and new bioactive ingredients from renewable sources, in particular from the Amazon region, that can be used to prepare cosmetic compositions for treating skin, hair and/or scalp. Said bioactive ingredients are obtained by means of a subcritical-water extraction process parameterized to obtain bioactive compounds from different species and different plant components.

Personal care compositions comprising malodor reduction compositions

The present invention relates to personal care compositions comprising malodor reduction compositions and methods of making and using such personal care compositions. Such personal care compositions comprising the malodor control technologies disclosed herein provide malodor control without leaving an undesirable scent and when perfume is used to scent such compositions, such scent is not unduly altered by the malodor control technology.

METHOD FOR IMPROVING THE SENSORIAL PROPERTIES OF OIL-IN-WATER EMULSIONS

Disclosed is a method for improving the sensorial and/or aesthetic properties of an oil-in-water type emulsion for topical application, the method including an effective quantity of a mixture of saturated cyclic or acyclic, linear or branched hydrocarbons of which at least 95% by weight have between fifteen and nineteen carbon atoms.

A LIQUID AND TRANSPARENT BLEND OF UV FILTERS
20220071872 · 2022-03-10 ·

Suggested is a liquid and transparent blend of UV filters, comprising, consisting or essentially consisting of (a) at least one solid UVA filter dissolved in (b) at least one liquid UVB filter exhibiting a linear UV absorbance curve with a variance of +/−10% in the range of 290 to 360 nm as measured from a solution containing 10 mg/l of said mixture in ethanol, wherein said solid UVA filters are selected from the group consisting of Avobenzone, Bemotrizinol and mixtures thereof.

Composition comprising resorcinol or derivative thereof
11154473 · 2021-10-26 · ·

The present invention relates to a composition, preferably a cosmetic composition, comprising: (a) at least one compound selected from the group consisting of resorcinol and resorcinol derivatives; (b) at least one lipophilic UV filter; (c) at least one lipophilic antioxidant; and (d) at least one oil. The composition according to one embodiment of the present invention is stable with regard to light and/or temperature.