The present invention relates to a method of extracting a low-molecular-weight proanthocyanidin using cranberries and lactic acid bacteria, and more particularly, the method may include (S1) growing and extracting a seed culture from cranberries, (S2) reinforcing the metabolism of a saccharide by adjusting a metabolic process, (S3) extracting the seed culture whose metabolic process is adjusted and culturing the extracted result, (S4) mixing cranberries, distilled water and a saccharide with the grown seed culture and fermenting the mixture, and (S5) extracting an unbound polyphenol from the fermented mixture.

A topical formulation comprising a Cannabis derived botanical drug product, wherein the concentration of each, cannabidiol and tetrahydrocannabinol, in the topical formulation is greater than 2 milligrams per kilogram.

Personal care compositions and methods for treating or reducing skin irritation or skin inflammation. The personal care composition may include a carrier, one or more plant oils, and a cannabinoid source. The one or more plant oils and the cannabinoid source may each be present in an effective amount to treat or reduce skin irritation or skin inflammation. The method for treating or reducing skin irritation or skin inflammation may include contacting the personal care composition with skin, and optionally, decreasing the amount of IL-1α in or on the skin.

A composition and methods for lubricating mucous membranes including reproductive tissue with a topical lubricant and at least one cannabinoid. Cannabis and cannabinoids are solubilized and combined with water-based personal lubricants.

Selected peptides have been found to repair, by means of nucleotide excision repair (NER), cellular DNA damaged by the exposure to external agents, in particular UV rays and are useful for cosmetic or pharmaceutical use thereof in skin treatment. Compositions for topical application that contain such peptides, preferably carried in liposomes, prevent and treat skin damage caused by the exposure to UV rays, including in subjects affected by xeroderma pigmentosum.

A dry extract of organic humified material for cosmetic, medical or dietary use, wherein the dry extract comprises fulvic acid and humic acid, and is characterized by a maximum average particle size of 20 micrometer.

The present invention relates to a composition having an anti-glycation effect and an application thereof. The anti-glycation composition includes the following constituents in parts by mass: 0.1 to 5 parts of Osmanthus fragrans extract, 0.1 to 5 parts of Punica granatum extract and 0.1 to 2 part of Olea europaea extract, wherein in the Osmanthus fragrans extract, a mass content of polyphenol is more than or equal to 10%, and a mass content of verbascoside is more than or equal to 10%; in the Punica granatum extract, a mass content of polyphenol is more than or equal to 30%, and a mass content of punicalagin is more than or equal to 8%; and in the Olea europaea extract, a mass content of polyphenol is more than or equal to 10%, and a mass content of hydroxytyrosol is more than or equal to 3%.

i) an alkali metal salt of an aldonic acid; ii) 0.1 to 5 wt %, citric acid by weight of the total composition; and iii) a surfactant; wherein the composition has a pH of from 3 to 5, provides repair to damaged internal protein of hair.

The present invention concerns an extract of Punica granatum comprising: i. at least 10% by weight of the total weight of the dry extract, of punicalagins; and ii. at least 10% by weight of the total weight of the dry extract, of ellagic acid; and wherein the weight ratio [ellagic acid/punicalagins] is ranging from 0.5 to 2.

The present invention also relates to a method of preparation of the said extract

Another object of the present invention is a preparation comprising the said extract and at least one water-miscible organic solvent preferably chosen from lower alcohols containing from 2 to 8 carbon atoms and in particular from 2 to 6 atoms.

The present invention also concerns a composition comprising the said extract or preparation; a process for the cosmetic treatment of keratin materials, comprising a step of applying the said composition and cosmetic uses of the said extract.

A method of preparing biocompatible and stable gold nanoparticles comprises preparing at least one flavonoid-rich plant extract, and mixing at least one of the plant extracts with an aqueous solution of at least one gold salt. The flavonoid-rich plant extract is an extract of Hubertia ambavilla or Hypericum lanceolatum. The gold nanoparticles may be used for medical and/or cosmetic purposes.