The present disclosure provides esters of a retinoid and an alcohol selected from the group consisting of tocopherols and tert-butylhydroquinone, such as esters of Formula (I). The present disclosure also provides compositions and kits comprising the esters, methods of producing the esters, and methods of using the esters (e.g., for treating or preventing a skin disease, slowing the ageing of the skin, improving the appearance of the skin, or modulating a retinoid receptor).

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The invention relates to a composition comprising melatonin, a metabolite or derivative thereof and coenzyme Q10 and to use thereof for the production of a pharmaceutical or cosmetic composition for the treatment of the skin, said composition potentiating the movement of both molecules into the mitochondrion and facilitating percutaneous absorption, in which both the melatonin and the CoQ10 can reach all of the strata of the skin.

The embodiments relate to improved skin quality, health and appearance using a new delivery method and certain bioactive compositions and formulations. The system incorporates microneedle delivery technology with unique compositions and formulations. Such development allows for the pursuit of personalized medicine, or treatment delivery that can expand to remote controlled environment, immediate compounding and ultimate personalization with a state of the art longitudinal data predictive analytics. Certain formulations described herein are unique, combinatory and synergistic. Secured by high-tech proprietary system, there are unlimited potentials using AQT technology including but not limited to 3-D printing of a biodegradable micro chips that can be delivered via injection, AQT or any other possible route.

A composition for reducing unpleasant odor, the composition includes betaine; musk; and N-Soya-N-ethyl morpholinium ethosulfate.

Provided herein are topical formulations including a cannabinoid and one or more active sunscreen ingredients. Also provided are methods of using the topical formulations.

An additive for use alone as a tablet or capsule or with a base product to produce an enhanced product that provides health benefits to a person who consumes or uses the additive, including stimulating naturally occurring enzymes in the person's body. The additive has one or more hydrogenated substances, such as Erythitol, Xylitol, hydrogenated dihydromyricetin and/or Quercetin dihydrate, and the flavonoid Dihydromyricetin. The flavonoid may be extracted from a Vine Tea plant and/or a plant chosen from the genus Hovenia, such as the Japanese raisin tree. The additive may also have one or more of a solvent, such as a bicarbonate compound or an alcohol solvent, a pH balancing acid and/or a preservatives. The base product may be a liquid, solid, powder, chewable, pharmaceutical, cosmetic or a lotion or other applied product. The enhanced product are a base product that is enhanced by the additive.

Nutraceutical composition for the activation of sirtuins in humans, the composition including from 10% by weight to 15% by weight of honokiol; from 12% by weight to 40% by weight of pterostilbene; from 22% by weight to 32% by weight of polydatin; from 25% by weight to 40% by weight of ellagic acid and from 1.5% by weight to 3% by weight of a mixture of zinc, seleniun, chromium and nicotinamide, the composition promoting the inhibition of cell degradation and aging phenomena.

A composition for topical application containing at least one combination of (a) polyphenols selected from proanthocyanidin monomers and oligomers (OPC), hydroxystilbenes, flavonoid monomers and oligomers, and derivatives and mixtures thereof, (b) a spruce extract having at least one lignan selected from: hydroxymatairesinol, secoisolariciresinol, conidendrin, lariciresinol and liovile. It also relates to the cosmetic use of such a combination for combating the signs of ageing of the skin or hair and nails or the effects of pollution, and a cosmetic treatment method using said combination.

The present invention features cosmetic compositions and a method for pigmentations that create realistic and long-wearing freckles on a user's skin. These compositions include advantages such as being applicable to various skin types. Other advantages include resistance to smearing and a more realistic appearance superior to alternative faux freckle solutions. These compositions can also be applied using various apparatuses.

Solid cleansing compositions and methods for treating, decreasing, reducing, or preventing hyperpigmentation of skin, and/or methods for regulating melanin in or on skin are provided. The solid cleansing composition may include a delivery vehicle and one or more whitening agents. The whitening agents may include one or more of kojic acid, phenylethyl resorcinol, or combinations thereof. The whitening agents may be configured to regulate melanin in or on skin, and the delivery vehicle may be configured to stabilize the one or more whitening agents.