A thrombus engagement tool having a flexible shaft, a clot engagement tip, and a handle. The engagement tip may include one or more radially outwardly extending structures such as a helical thread. The helical thread can be advanced through a catheter to engage a clot. The handle may be configured to be rotated by hand. When the handle is rotated, the helical thread of the engagement tip can rotate in the same direction thereby allowing the helical threat to engage the clot. The helical thread can wrap around the flexible shaft at least about one, two, or four or more full revolutions, but in some cases no more than about ten or no more than about six revolutions.

A clot capture module can include a housing, a chamber inside the housing, a window, and a filter. The window permits visual inspection of a clot inside the chamber. The clot can access the chamber via an incoming flow path configured to direct blood from an aspiration catheter to an upstream surface of the filter. An aspiration control valve can block the flow of incoming aspirated blood until actuated to permit inflow of aspirated blood. An outgoing flow path can direct blood from a downstream surface of the filter to a remote vacuum canister.

A clot capture module can include a housing, a chamber inside the housing, a window, and a filter. The window permits visual inspection of a clot inside the chamber. The clot can access the chamber via an incoming flow path configured to direct blood from an aspiration catheter to an upstream surface of the filter. An aspiration control valve can block the flow of incoming aspirated blood until actuated to permit inflow of aspirated blood. An outgoing flow path can direct blood from a downstream surface of the filter to a remote vacuum canister.

A clot capture module can include a housing, a chamber inside the housing, a window, and a filter. The window permits visual inspection of a clot inside the chamber. The clot can access the chamber via an incoming flow path configured to direct blood from an aspiration catheter to an upstream surface of the filter. An aspiration control valve can block the flow of incoming aspirated blood until actuated to permit inflow of aspirated blood. An outgoing flow path can direct blood from a downstream surface of the filter to a remote vacuum canister.

Aspiration systems and methods for controlling blood loss during thrombus removal are disclosed herein. The systems include an aspiration catheter, an aspiration tubing, a receptacle for collecting aspirated blood, a vacuum line coupled to the receptacle, and a sensor configured to measure a flow parameter associated with a liquid within an aspiration lumen. The systems further include a regulator configured to adjust a vacuum pressure within the vacuum line, and a vacuum controller operably coupled to the sensor and the regulator. The vacuum controller is configured to receive the flow parameter from the sensor, compare the flow parameter to a target range for the flow parameter, and send an automatic control signal to the regulator based on a comparison of the flow parameter to the target range. The automatic control signal causes the regulator to adjust the vacuum pressure within the vacuum line.

A system and method for automatically removing by suction urine voided by a female. The system includes an integrated external catheter and suction regulator unit. The external catheter is applied at the female's urethra opening to receive urine voided by the female. The suction regulator is connected to a receptacle for collecting the urine and is operative to regulate suction applied to the canister from a hospitals' suction line to a regulated value which is applied the external female catheter, whereupon urine from the external female catheter is carried by the regulated suction through the suction regulator and into the receptacle. The external catheter includes an internal suction tube and an external removable and replaceable liquid permeable cover located on the internal suction tube. The external catheter is malleable so that it can be conformed to the anatomy of the female.

An extension conduit for use with a system for aspirating thrombus includes a passageway extending between a distal end and a proximal end of the extension conduit, and a combined hydraulic and electrical control carried on the extension conduit and configured to be activated by a user to activate an electric switch while opening a valve to allow flow through the passageway.

Aspiration systems and methods for controlling blood loss during thrombus removal are disclosed herein. The systems include an aspiration catheter, an aspiration tubing, a receptacle for collecting aspirated blood, a vacuum line coupled to the receptacle, and a sensor configured to measure a flow parameter associated with a liquid within an aspiration lumen. The systems further include a regulator configured to adjust a vacuum pressure within the vacuum line, and a vacuum controller operably coupled to the sensor and the regulator. The vacuum controller is configured to receive the flow parameter from the sensor, compare the flow parameter to a target range for the flow parameter, and send an automatic control signal to the regulator based on a comparison of the flow parameter to the target range. The automatic control signal causes the regulator to adjust the vacuum pressure within the vacuum line.

Aspiration systems and methods for controlling blood loss during thrombus removal are disclosed herein. The systems include an aspiration catheter, an aspiration tubing, a receptacle for collecting aspirated blood, a vacuum line coupled to the receptacle, and a sensor configured to measure a flow parameter associated with a liquid within an aspiration lumen. The systems further include a regulator configured to adjust a vacuum pressure within the vacuum line, and a vacuum controller operably coupled to the sensor and the regulator. The vacuum controller is configured to receive the flow parameter from the sensor, compare the flow parameter to a target range for the flow parameter, and send an automatic control signal to the regulator based on a comparison of the flow parameter to the target range. The automatic control signal causes the regulator to adjust the vacuum pressure within the vacuum line.

A system and method for automatically removing by suction urine voided by a female. The system includes an external catheter. The external catheter includes a suction tube having a portion enclosed in a hydrophilic sponge cover. The suction tube is arranged to be coupled to suction of a desired value. The cover is arranged to be disposed externally at the female's urethra opening to receive urine voided by the female, whereupon the suction draws the urine through the cover into the suction tube. The external catheter is arranged to be connected to a receptacle for collecting the urine received by the external catheter. Various embodiments of the suction tube and the cover are disclosed.