The subject technology is embodied in a method for predicting a delivery rate of a plurality of drugs dispensed by multiple infusion pumps at a delivery point. The method includes receiving one or more operating parameters related to multiple drug pumps and a carrier fluid pump, wherein each of the drug pumps dispenses a drug, and the carrier fluid pump dispenses a carrier fluid. The method also includes determining a delivery rate of a first drug at the delivery point. This can be done by predicting time variation of a concentration of the first drug at the delivery point based on a mathematical model of a mixed flow through a fluid path that terminates at the delivery point. The mixed flow includes the drugs and the carrier fluid. The model includes the operating parameters and a plurality of flow-parameters related to the mathematical model of the mixed flow.

The invention relates to an apparatus comprising an electromechanical device, a control unit, a main control unit and a motion detector, wherein said control unit is configured to control said electromechanical device. The invention also relates to a method for operating an apparatus with a main control unit, a control unit and an electromechanical device. The technical problem of providing an apparatus with an electromechanical device, the reliability of which is improved, is solved by an apparatus wherein the main control unit is configured to provide information to the control unit. The motion detector and the main control unit are configured such that information about the movement of the electromechanical device is provided by the motion detector at least to the main control unit. The technical problem is also solved by a method for operating an apparatus, in particular an apparatus or medical device according to the invention.

A fluid path set including a multi-patient use section adapted for connection with a pump device and a source of injection fluid, and a per-patient use section adapted for removable fluid communication with the multi-patient use section. The per-patient use section includes a pressure isolation mechanism having a first port adapted for connection to the pump device via the multi-patient use section, a second port adapted for connection to a patient, and a pressure isolation port adapted for connection to a source of medical fluid via the multi-patient use section. The per-patient use section includes a valve member biased to a normally open position permitting fluid communication between the first port, the second port, and the pressure isolation port, and movable to a closed position to close the pressure isolation port when fluid pressure reaches a predetermined pressure level sufficient to overcome a biasing force applied to the valve member.

A method of predicting peak pressure within a fluid path, which includes a tubing set and a catheter into which at least one fluid is introduced under pressure by a pressurizing system of a fluid injection apparatus, includes (a) inputting an initial injection protocol into the fluid injection apparatus according to which the at least one fluid is intended to be introduced into the fluid path; (b) predicting an expected peak pressure level that would result in the fluid path if the initial injection protocol were to be used as intended to introduce the at least one fluid into the fluid path. The expected peak pressure level is determined before commencement of the initial injection protocol according to at least one model on the basis of a flow rate of the at least one fluid, at least one catheter characteristic, and a viscosity of the at least one fluid. The at least one model is determined experimentally for a plurality of fluids of different viscosities, for a plurality of catheters of different catheter characteristics, and for at least one tubing set of like kind to the tubing set of the fluid path.

A disposable, wearable, self-contained insulin dispensing device includes a housing and an insulin source in the housing that is connected to a catheter for injecting insulin into a user.

Systems and methods for suppressing electrical noise in an electrocardiogram (ECG) signal obtained by at least one electrode and displayed on an ECG monitor are disclosed. The system includes a conductive material distinct from the at least one electrode and configured to contact a surface of a patient, and filtering circuitry connected in series between the conductive material and ground. The filtering circuitry may be configured to filter to ground the electrical noise present within the patient before it is received by the at least one electrode and is prevented from distorting the ECG signal that is displayed on the ECG monitor.

An engagement mechanism associated with a reciprocally movable piston of a fluid injector is configured for releasably engaging an engagement portion at a proximal end of a rolling diaphragm syringe having a flexible sidewall configured for rolling upon itself when acted upon by the piston. The engagement mechanism has a plurality of engagement elements reversibly and radially movable relative to the engagement portion of the syringe between a first position, where the plurality of engagement elements are disengaged from the engagement portion of the syringe, and a second position, where the plurality of engagement elements are engaged with the engagement portion of the syringe. The engagement mechanism further has a drive mechanism for moving the plurality of engagement elements between the first position and the second position.

A method of predicting peak pressure within a fluid path, which includes a tubing set and a catheter into which at least one fluid is introduced under pressure by a pressurizing system of a fluid injection apparatus, includes (a) inputting an initial injection protocol into the fluid injection apparatus according to which the at least one fluid is intended to be introduced into the fluid path; (b) predicting an expected peak pressure level that would result in the fluid path if the initial injection protocol were to be used as intended to introduce the at least one fluid into the fluid path. The expected peak pressure level is determined before commencement of the initial injection protocol according to at least one model on the basis of a flow rate of the at least one fluid, at least one catheter characteristic, and a viscosity of the at least one fluid. The at least one model is determined experimentally for a plurality of fluids of different viscosities, for a plurality of catheters of different catheter characteristics, and for at least one tubing set of like kind to the tubing set of the fluid path.

An injection system has: a gasket having multiple engaging claws, and a distal end portion having across-sectional shape in which a length in a height direction of the cross-sectional shape is longer than a length in a width direction; a ram engaged with the gasket; a cylinder into which the gasket is inserted; and an injection device configured to move the ram and injecting a chemical solution in the cylinder. Each of the engaging claws includes an inner surface which defines a hole having an inlet with an enlarged diameter and inclined in a direction away from a perpendicular line passing through a center of the hole. The engaging claws are displaced between a widened position and a narrowed position. Two engaging claws aligned in the height direction have the same shape and size, and two engaging claws aligned in the width direction have the same shape and size.

A syringe includes a barrel, a plunger, and a sealing member creating a seal between the plunger and the barrel. The barrel includes a first portion with a first inner diameter and a second portion with a second inner diameter that is larger than the first inner diameter. The sealing member engages the first portion of the barrel to give rise to a first contact pressure when the barrel is filled with product. The first contact pressure is sufficient to maintain a gas-tight seal over the expected temperature ranges −25° C. to 40° C. A first force is applied to the plunger to overcome the first contact pressure and move the plunger out of the first portion and into the second portion to dispense product. The sealing member engages the second portion of the barrel to give rise to a second contact pressure that is lower than the first contact pressure. A second force lower than the first force is sufficient to overcome the second contact pressure and move the plunger in the second portion to continue dispensing product. The syringe may include a restraining element for accommodating expansion of the product during freezing.