A temperature compensation flow-limiting device are provided. The temperature compensation flow-limiting device is disposed in the infusion tube of the elastomeric infusion system to improve instability, caused by changes to temperature, of the flow velocity of the fluid inside the infusion tube to keep the flow velocity of the fluid stable. The temperature compensation flow-limiting device includes an inner layer and an outer layer; the coefficient of thermal expansion (CTE) of the inner layer is greater than that of the outer layer. When the temperature of the fluid inside the infusion tube increases, the inner layer expands and the internal diameter decreases as it is limited by the outer layer.

A temperature compensation flow-limiting device are provided. The temperature compensation flow-limiting device is disposed in the infusion tube of the elastomeric infusion system to improve instability, caused by changes to temperature, of the flow velocity of the fluid inside the infusion tube to keep the flow velocity of the fluid stable. The temperature compensation flow-limiting device includes an inner layer and an outer layer; the coefficient of thermal expansion (CTE) of the inner layer is greater than that of the outer layer. When the temperature of the fluid inside the infusion tube increases, the inner layer expands and the internal diameter decreases as it is limited by the outer layer.

A device for infusion of medical fluids is provided. It has an internal reservoir for a fluid to be administered made of a first flexible base material to vary its volume as a function of the quantity of fluid present thereinside; and an outer casing containing the reservoir, having a side wall made of a second elastic base material suitable to make elastically deformable the casing to vary the geometry and internal volume thereof as a function of the volume of the reservoir.

A device for infusion of medical fluids is provided. It has an internal reservoir for a fluid to be administered made of a first flexible base material to vary its volume as a function of the quantity of fluid present thereinside; and an outer casing containing the reservoir, having a side wall made of a second elastic base material suitable to make elastically deformable the casing to vary the geometry and internal volume thereof as a function of the volume of the reservoir.

A pump device for conveying medical fluid includes an elastomeric membrane forming a pump volume. The membrane is elastically expanded in a filling state of the pump volume with medical fluid. The expanded membrane exerts a delivery pressure on the pump volume to deliver medical fluid into a fluid-line system. The pump device also has a throttle device with a channel having an inlet connected to the pump volume and an outlet connectable to the fluid-line system. Delivery of medical fluid through the outlet is finely adjustable to a defined flow rate at the time of manufacture. The throttle device has a first body and a second body. The channel is formed between oppositely arranged surfaces of the bodies. The surfaces are movable relative to each other for fine adjustment of the flow rate at the time of manufacture, so that an effective length of the channel is variable.

A pump device for conveying medical fluid includes an elastomeric membrane forming a pump volume. The membrane is elastically expanded in a filling state of the pump volume with medical fluid. The expanded membrane exerts a delivery pressure on the pump volume to deliver medical fluid into a fluid-line system. The pump device also has a throttle device with a channel having an inlet connected to the pump volume and an outlet connectable to the fluid-line system. Delivery of medical fluid through the outlet is finely adjustable to a defined flow rate at the time of manufacture. The throttle device has a first body and a second body. The channel is formed between oppositely arranged surfaces of the bodies. The surfaces are movable relative to each other for fine adjustment of the flow rate at the time of manufacture, so that an effective length of the channel is variable.

A method and a system comprising an integrated water purifying apparatus with a pre-filter circuit including a particle filter and an activated carbon filter arranged to produce pre-treated water; a fluid circuit arranged to receive pre-treated water from the pre-filter circuit, the fluid circuit including an RO-pump and a Reverse Osmosis (RO) device arranged to produce purified water; a heating device arranged to heat purified water from the RO device to a temperature above 65°0 C.; the water purifying apparatus further arranged to heat disinfect the fluid circuit using the heated purified water. The system further comprises a line set connected to the purified water outlet connector at a water line connector of the line set, wherein the line set includes at least one sterile sterilizing grade filter arranged to further filter the purified water.

A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

The present disclosure provides high concentration low viscosity defibrotide formulations administered via an automated injection device. The device is calibrated for optimum flow rate and administration of the high concentration low viscosity formulation.

The present disclosure provides high concentration low viscosity defibrotide formulations administered via an automated injection device. The device is calibrated for optimum flow rate and administration of the high concentration low viscosity formulation.