The invention relates to a piercing means protective device for a syringe having a syringe body and a piercing means arranged at the distal end of the syringe body, comprising a dimensionally stable sleeve element, which extends along an axial direction and at least partially encloses an inner element extending along an axial direction, wherein the inner element consists of a resilient material and at least partially encloses the piercing means. The piercing means protective device is characterised in that a connection element connected to the sleeve element has at least one projection extending in an axial direction, which projection is received at least in portions in a recess of the inner element, so that a connection with a force fit and/or an interlocking fit exists between the sleeve element and the inner element.

A multi-chamber injection device includes multiple syringes. The multiple syringes may be arrayed in a circular, linear, or other format. In some implementations, a needle, port, or similar may be shared by all the syringes in configuration that allows only one syringe to deliver contents at a time while blocking the other syringes from delivering their respective contents. In some implementations, the syringes may be all stored in the same container. One or more of the chambers of a multi-chamber injection device may be preloaded with medication. Different medications may be loaded into different chambers. The medications may be selected to treat the same medical condition.

Described is a needle shield assembly comprising an inner body adapted to receive a needle and an outer body coupled to the inner body. The inner body comprises a proximal portion having a first outer diameter (D4) and a distal portion having a second outer diameter. The first outer diameter is larger than the second outer diameter. The outer body has a third outer diameter (D3) substantially equal to or less than the first outer diameter.

An injection device is described having a housing that receives a syringe having a boot that covers its needle. The syringe is biased by a return spring from an extended position to a retracted position. A drive spring advances the syringe from its retracted position to its extended position. A return spring restores the syringe to its refracted position. A releasable locking mechanism retains the syringe in its refracted position. A sleeve can be depressed to release the locking mechanism. A cap covers the sleeve, thus preventing the locking mechanism from being released. When the cap is removed, it takes the boot with it and no longer prevents the locking mechanism from being released. Then, the locking mechanism can be released and the injection cycle begun.

A disposable, wearable, self-contained insulin dispensing device includes a housing and an insulin source in the housing that is connected to a catheter for injecting insulin into a user.

The disclosure relates to a needle cover for protecting a needle mounted on a tip of a medical injection device. The tip comprises a distal bulge. The needle cover comprises an inner needle shield made of a material with elastomeric properties. The inner needle shield comprises an inner sealing portion configured to sealingly contact the outer surface of the bulge, wherein the inner sealing portion comprises one or more ribs extending inwardly along the circumference of the inner sealing portion. At least one rib is a continuous rib in the form of a ring configured to provide a continuous contact with the outer surface of the bulge.

A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O.sub.2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.

A rigid needle shield for a syringe includes a main body comprising an internal sidewall defining a bore, and an end cap attached to the main body. The end cap includes at least one frangible tab connected to the sidewall of the main body. The rigid needle shield further includes an elastomeric insert extending through the bore and engaging the end cap. The at least one frangible tab is configured to break from the internal sidewall and advance through the bore upon application of a force to the end cap.

A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O.sub.2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.

A medical injector including a cap remover or second cap is disclosed. The medical injector includes an injector housing defining a reservoir, a plunger rod, and a stopper engaged with a portion of the plunger rod and slidably disposed within the reservoir. The stopper being sized relative to an interior of the injector housing to provide sealing engagement with a sidewall of the injector housing. The medical injector further includes a needle having a sharpened first end and a second end in communication with the reservoir, a first cap covering the sharpened first end of the needle, and a second cap covering at least a part of the first cap. The second cap is engaged with the first cap such that removal of the second cap simultaneously removes the first cap from the first end of the needle.