A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal key, and a dose stop member engaging the dose set knob. Rotation of the dose set knob to set a medication dose causes rotation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.

A drive mechanism for a drug delivery device with a reduced operating loudness includes a dose selector, a housing, and a ratchet with a gear element comprising a plurality of gear teeth connected with the dose selector and a pawl element rotationally constrained to the housing comprising at least one pawl tooth. The at least one pawl tooth engages with the gear teeth and is located opposite to the gear teeth. One of the gear element and the pawl element moves forth and back relative to the other element of the gear and pawl elements along a first direction for de-engagement and re-engagement of the opposite gear teeth and at least one pawl tooth when the gear element rotates relative to the housing during dose setting using the dose selector. The pawl element and/or gear element comprises a noise reduction characteristic at a surface which dampens the noise produced.

Disclosed herein are delivery devices for delivering a volume of a drug product, placebo product, or other product including a fluid. The devices may include a barrel having a longitudinal axis, a proximal end region, and a distal end region. The proximal end region may include an opening, and the barrel may be configured to receive a drug therein. A plunger rod may be disposed at least partially inside the barrel and protruding from the opening. The plunger rod may include a rack having a plurality of teeth. The device may further include a pinion having a plurality of teeth configured to engage with the plurality of teeth of the rack, and rotation of the pinion against the rack may move at least a part of the plunger rod along the longitudinal axis of the barrel.

Various handheld medical dispensing configurations and methods including the following: Handheld medical dispensing system comprises a syringe, which has a plunger, releasably mounted to syringe actuation apparatus, the apparatus having an actuator configured such that it can move the plunger more than once to dispense a plurality of amounts of substance from the syringe and having a housing adapted for singled handed administration of an injection.

An automatic administration instrument includes a syringe and a partition wall in the syringe which partitions the syringe into different rooms for respectively holding plural kinds of drug solutions or a drug and a drug solution. A partition-wall driver displaces the partition wall and an injection needle is connected to the syringe. A body cap attached to the administration instrument body so as to cover the injection needle. The syringe, the partition wall, and the body cap are configured such that displacing the partition wall dissolves or mixes the drug solutions or the drug and the drug solution in a state that the injection needle is covered by the body cap.

An administration instrument includes an injection button which can be pressed at an angle that is not parallel to a needle with respect to a direction in which the needle is inserted into skin. As a result, it is possible to prevent a force of pressing the injection button from being transmitted in the direction in which the needle is inserted into the skin deeper than initial insertion of the needle, thereby achieving an administration under a stable state.

An injection assembly includes a housing with a barrel positioned within the housing. The barrel includes an axis extending from a proximal end to a distal end thereof and a chamber for storing medicine. An elongate anti-rotation shaft is rotationally fixed to the housing and has a non-circular cross-section. The injection assembly includes an inner screw having an inner screw opening to complementarily receive the anti-rotation shaft to prevent rotation of the inner screw with respect to the anti-rotation shaft but allow respective linear translation along the axis. An outer screw is positioned within, and rotatable with respect to, the housing and has an outer screw opening to threadably receive the inner screw, wherein rotation of the outer screw translates the inner screw along the axis and along the anti-rotation shaft. A plunger is coupled to the distal end of the inner screw and is moveable with respect to the chamber to push the medicine out of the chamber when the outer screw is rotated.

A single hand operable injection control device (ICD) automatically injects material into a subject tissue at a rate controllably proportional to the rate of movement of the syringe. Squeezing the figure holds rotates a transmission/timing belt that is connected to a position reference member/guide that pushes against the subject tissue, causing the ICD body (containing the syringe) to push away from the subject tissue. The timing belt turns a worm gear that drives a syringe plunger into the syringe held by the ICD. The coordinated motions result in precise delivery of a unit volume/region of injectate into the subject. That is, a uniform “tube” of injectate is automatically laid in the cannula track.

A medication delivery device is disclosed including a rack-and-pinion plunger drive system. The drive system includes an output drive having a pawled end movably coupled with the ratchet teeth of the plunger, and a pinion drive coupled between the housing, the output drive and an actuator. Actuator is longitudinally movable between dose set and delivery positions. Movement of the actuator causes rotation of the pinion drive along the rack to translate the output drive member with the pawled end that is engaged with the plunger ratchet teeth to distally advance the plunger. The device may include one or more of an end of dose mechanism to limit travel of the actuator, a load brake system to stop travel of the plunger under high input forces, a dose detection system, and a dose selector to vary the amount of dose set.

Injection device and method for monitoring injection information relating to an injection. A syringe of the device includes a syringe chamber containing an injectant substance. A plunger of the device includes a plunger rod axially displaceable within the syringe chamber. At least one element of the is configured to undergo a corresponding element motion linked to a distal displacement of the plunger rod. A sensor of an electronics unit of the device obtains detection readings relating to the corresponding element motion. An injection is performed by depressing the plunger rod in a distal direction, compelling a corresponding element motion detected by the sensor, and compelling the injectant substance to be injected through a distal end of the syringe chamber. The detection readings relating to the corresponding element motion of the element is processed to determine injection information including at least the volume of injectant substance injected.