An applicator has at least one barrel and a piston moveable within the at least one barrel between a variable first position and a second position. Movement of the piston towards the first position can draw a first fluid into the barrel, and movement of the piston towards the second position can force the first fluid out of the barrel. A fluid inlet valve allows the fluid to flow into the barrel at least under action of the piston, and a fluid outlet valve allows the fluid to flow out of the barrel. The piston is biased toward the first position and a dosage control part. An actuator is operable to move the piston to dispense the first fluid from the applicator.

A pen injector apparatus is disclosed for use with a cartridge to deliver a plurality of single metered doses therefrom. The injector apparatus includes a body arranged to provide a conduit which, in use, provides a fluid communication path between the cartridge and a delivery needle and a mechanism arranged to expel therapeutic material from the cartridge. The mechanism is arranged to draw therapeutic material from the cartridge into the conduit by negative pressure and discharge a metered dose from the conduit via the delivery needle.

An injector apparatus is disclosed for use with a container of therapeutic material to deliver a metered dose of therapeutic material therefrom. The apparatus includes a first body portion arranged to be fixed relative to the container and defining a first conduit portion for the delivery of the therapeutic material from the container and a second body slidably connected to the first body and defining a second conduit portion, in fluid communication with the first conduit portion. Relative sliding motion between the first body and second body results in the displacement of one of the conduit portions into the other conduit portion such that the combined volume of the conduit may be decreased.

The syringe dispenser includes a syringe and a plunger. The plunger includes a first shaft member including a piston and second shaft member configured to be fitted in a tubular portion of the first shaft member. The first shaft member includes an elastic piece, the elastic piece being provided with a slide projection configured to slide on an inner surface of the syringe and a lock projection configured to be locked against the syringe. The second shaft member includes a pressing shaft configured to be fitted in the tubular portion. The pressing shaft is provided in a front end thereof with an end surface configured to press a free end of the elastic piece. In response to pressing from the end surface, the lock projection is locked against the rear end of the syringe, and in response to the pressing being released, the locking of the lock projection is released.

Devices for delivery of individual units of a medicament and methods for their use are provided. Such a delivery device comprises an exostructure permanently attached to a syringe comprising a barrel and a plunger with one or more ratchet surfaces, a cam mechanism to advance the plunger a plurality of set distances in a first direction to deliver a single individual unit of the medicament per each set distance, and a locking pawl to prevent the plunger from being retracted in a second direction opposite the first by interfacing with the ratchet surfaces. The locking pawl also produces tactile feedback, audible feedback, or both when the plunger is depressed to advance the plunger the set distance. Each of the individual units comprise a measured volume of the medicament, and the plunger can repeatedly be depressed and repeatedly engage with the locking pawl to deliver repeated measured volumes of the medicament.

A plunger-like mass transporting device and method for controllable transportation of a selected dosage of a solid or liquid composition having a body with a rigid enclosure, and a head, where the head is configured to attach to the body, the head having a stem and a housing. Further, the stem having a first end, the first end having an attachment means to attach to the rigid enclosure containing the body; and a second end, the second end having an attachment means to attach to the housing, and an applicator; wherein a flexible means is disposed on the stem, for providing an up position and a down position during an axial movement of the stem back and forth through the housing, wherein the housing contains the solid or liquid composition.

A handheld injection device includes a housing and a dose indicator positioned within and axially constrained to the housing and rotatable with respect to the housing during dose setting and during dose dispensing. The dose indicator includes a flexible clicker arm which, only during dispense, is displaced in a first radial direction and, when the device reaches its minimum dose position, in a second, opposite radial direction.

The invention relates to an autoinjector for dispensing a liquid product, in particular a highly viscous medication, comprising: a housing, a product container, which is arranged in the housing and has a slidable piston, wherein the piston can be slid in a dispensing direction in order to dispense the product contained in the product container, a forward drive element, which acts on the piston as the product is being dispensed, a first spring, which is preloaded such that the product can be dispensed from the product container by the sliding of the forward drive element and the piston, and a rotation element, which is operatively coupled to the forward drive element, wherein the first spring acts on the rotation element in such a way that the rotation element is set into rotation in order to dispense the product, wherein the rotation element or the forward drive element has a thread having a variable pitch.

A chemical-liquid injector includes a piston-driving mechanism (130) that moves a piston member of a syringe containing a contrast medium, which includes an actuator and a ram member which is moved back and forth by the actuator, a control circuit (150) which is electrically connected to the actuator, and an operating knob unit (170) which includes an operating knob that is to be operated by an operator, and a rotation sensor that outputs an electric signal corresponding to a rotation of the operating knob. The control circuit is configured to generate a predetermined control signal accordingly, on the basis of a signal from the rotation sensor, and the piston-driving mechanism is operated according to the control signal.

Mixing systems for producing a mixture to deliver to a treatment site. An illustrative system may comprise a needle hub and a multi-reservoir system. The multi-reservoir system may comprise a first plunger assembly, a second plunger assembly, and a barrel portion. The first plunger assembly, the second plunger assembly, and the barrel portion may be assembled in a telescoping arrangement. Advancing the first plunger assembly may cause a first constituent to be delivered from a first reservoir of the second plunger assembly into the third reservoir to mix with a third constituent to form a precursor and a second constituent to be delivered from a second reservoir of the second plunger assembly into the fourth reservoir and advancing the first and second plunger assembly collectively causes the precursor and the second constituent to be delivered into the needle hub.