A thread lift cannula has a plurality of therapeutic liquid discharge ports to enable the discharge of a therapeutic liquid into the surrounding tissue. The therapeutic liquid may be injected into the thread lift cannula conduit by a syringe and the thread therein may be bioresorbable and absorb the therapeutic liquid. The therapeutic liquid may include a medicament to reduce swelling or to treat pain, or a biologic that aids in collagen creation, formation, or restructuring. The plurality of therapeutic liquid discharge ports may vary in size along the length of the cannula. A distal discharge port may be larger than a proximal discharge port to enable a more uniform delivery of therapeutic liquid along the cannula. A therapeutic liquid discharge port may be configured at a port angle, offset from orthogonally through the wall of the cannula, to prevent blockage of the outlet opening of the discharge port.

Disclosed embodiments include apparatuses and methods for using a tip member to deposit or collect a supply of material from within a body. In an illustrative embodiment, an apparatus includes a tip body defining an annular chamber. A tip receptacle is configured to be joinable with a lumen and to receive a fluid flow therethrough and to convey the fluid flow into the annular chamber. A material distribution element is fluidly coupled with the annular chamber, wherein when the fluid flow is introduced into the annular chamber. The material distribution element diffusively passes the fluid flow out of multiple egress points in at least one of a distal end and a lateral surface of the tip body.

Disclosed is a fluid delivery device including a fluid reservoir and a transcutaneous access tool fluidly coupled to the fluid reservoir, wherein the transcutaneous access tool includes a needle or a trocar. The fluid delivery device may further include a transcutaneous access tool insertion mechanism for deploying the transcutaneous access tool, wherein the insertion mechanism is configured to insert and retract the needle/trocar in a single, uninterrupted motion.

Infusion devices and methods are provided for a drug delivery system and can include an infusion needle (1) having a tip end (2) and a drive unit (D) coupled to the infusion needle and arranged for advancing the tip end of the infusion needle to penetrate any fibrosis when the infusion device is implanted in a patient's body. The infusion needle and drive unit are designed for implantation in a patient's body. Other components of the drug delivery system may be part of the implantable infusion device or, alternatively, be for extracorporal use cooperating with the implanted infusion device. Preferably, the infusion needle can be advanced and retracted with each infusion cycle. Furthermore, upon each advancement and/or retraction, the needle may be moved laterally so as to vary the injection site. Needle (1) and drive unit (D) are preferably disposed within a body (15), with the infusion needle being arranged for penetrating a self-sealing penetration membrane (18).

Disclosed herein are embodiments of spring cannulae, including one or more holes in the sidewall of the cannula. Some disclosed cannulae include a wire, helically wound to form coils, and at least one hole in the cannula that interrupts one or more of the coils. Some embodiments further include a fused region of the coils through which the hole passes. Some embodiments include a ring attached to ends of the interrupted coils, where the hole is surrounded by the ring. Some embodiments include a sheath that is attached to a radial surface of the interrupted coils, where the hole passes radially though the sheath.

Devices, systems, and methods are provided herein for delivering medication (e.g., insulin) via a wearable pump having a patch-style form factor for adhesion to a user's body. The reusable pump may be coupled to a disposable cap housing a microdosing system for delivering precise, repeatable doses of medication to a cannula configured to deliver medication to a target infusion area beneath the user's outer skin layer. The system further may include an applicator for inserting the cannula into the user's skin and/or applying an adhesive pad to the skin.

Devices, systems, and methods are provided herein for delivering medication (e.g., insulin) via a wearable pump having a patch-style form factor for adhesion to a user's body. The reusable pump may be coupled to a disposable cap housing a microdosing system for delivering precise, repeatable doses of medication to a cannula configured to deliver medication to a target infusion area beneath the user's outer skin layer. The system further may include an applicator for inserting the cannula into the user's skin and/or applying an adhesive pad to the skin.

Exemplary embodiments may provide a medicament delivery device that includes a single instrument for piercing the skin of the user and for acting as a conduit for delivering medicament to the user subcutaneously. The exemplary embodiments may reduce discomfort caused by a rigid cannula or needle. The exemplary embodiments may provide instruments that are configured to be comfortable to the user when the instruments are in place beneath the skin of the user, such as when a medicament delivery device is delivering medicament to the user.

An injection needle including a shaft extending between a hub end, an injection end, and a lumen formed within the shaft. The lumen forms an opening that extends through the shaft from the hub end to the injection end. The injection end includes a bevel having a point and a heel, with the opening formed by the lumen passing through the bevel. Multiple slots may be formed within the shaft close to the injection end and near the bevel. The multiple slots may include a first group on one side of the shaft and a second group on an opposing side of the shaft.

Provided herein are methods for providing a therapeutic benefit to a patient. A method of treating a patient with a metabolic disease and/or a pancreatic disease includes: selecting a patient with a metabolic disease and/or a pancreatic disease; selecting one or more pancreatic deposit sites; advancing a depositing device comprising a at least one depositing element to the selected one or more pancreatic deposit sites; and delivering a treatment agent through the at least one depositing element into the selected one or more pancreatic deposit sites. Systems and devices are also described.