The disclosed guidewire includes a wire main body possessing an elongated shape and a cylindrical body possessing a cylindrical shape. The distal portion of the wire main body is positioned in the cylindrical body. The guidewire has an inner coil disposed between the wire main body and the cylindrical body. The inner coil includes a wire rod wound in a spiral shape along the outer circumferential portion of the wire main body. There is an interval between the wire rods adjacent to each other in a longitudinal direction of the wire main body that is adjustable. The guidewire also has an operation member that changes the interval between the wire rods of the inner coil.

A guidewire for a medical device is disclosed. The guidewire includes an elongate body, a proximal connector assembly, a corewire, and a sensor assembly. The body has an annular wall that defines an interior lumen. The proximal connector assembly is coupled to the body and is configured for connection to a medical positioning system. The corewire extends through the lumen. The sensor assembly located on a distal end of the corewire is electrically connected to the proximal connector assembly. The sensor assembly is configured to generate an electrical signal indicative of a position of the sensor assembly in a reference coordinate system defined by the medical positioning system. The body includes a helical cutout extending over a predetermined length of the body. The helical cutout is configured to increase the flexibility of the body over the predetermined length of the body.

A medical guidewire system including an inner member having an outer diameter and an outer member having an inner diameter, the inner diameter being larger than the outer diameter. The inner and outer members are relatively slidable to adjust a stiffness of the guidewire system. The lumen of the outer member forms a gap for fluid flow therethrough. A connector to the inner member and a fluid infusion channel communicating with the gap for injection of fluid through the gap to exit a distal portion of the outer member.

An apparatus and method of manufacture includes a helical wire coil and a core wire. The core wire has a first wire portion and a second wire portion. The first wire portion of the core wire extends through the helical wire coil. The second wire portion of the core wire is intertwined with the first helical wire coil to fixedly secure the core wire relative to the first helical wire coil. The core wire is formed from a first material that is non-extensible. The core wire is fixedly secured relative to a distal portion of the helical wire coil such that the core wire inhibits longitudinal elongation of the helical wire coil along a longitudinal coil axis.

An apparatus and method of manufacture includes a helical wire coil and a core wire assembly. The core wire assembly includes a core wire and a sleeve. The core wire extends through the helical wire coil and is formed from a first material that is non-extensible. The sleeve has a longitudinal bore. The core wire is disposed within the longitudinal bore of the sleeve. The core wire is secured within the sleeve. The sleeve is formed from a second material. The second material of the sleeve is different than the first material of the core wire. The sleeve is attached to the distal wire coil such that core wire inhibits longitudinal elongation of the proximal and distal wire coils along the longitudinal coil axis.

The present invention relates to a method of delivering drugs having e.g., anti-proliferative activity in the vascular, preferably, the cardiovascular, system locally or systematically using an at least partially drug-coated guidewire. The drug-coated guidewire, particularly an expansion member or portion thereof, is brought into contact with the target tissue or in circulation and the drugs are quickly released into the area surrounding the device in a short time after the contact step. Once the therapeutic drugs are released, they are quickly and effectively absorbed by the surrounding cells or circulation.

An access sleeve can be attached to a medical device having first and second ends, the first end being positioned inside of a patient and the second end being positioned external to a patient. The access sleeve can include a tubular sleeve body having first and second open ends that define a first lumen extending along a longitudinal axis of the sleeve body. An opening in the sleeve body can connect the first lumen to an outer surface of the sleeve body. The access sleeve can be selectively attached to the medical device (e.g. catheter of a heart pump) and inserted into the access site when the medical device is positioned in the patient. The access sleeve can maintain vascular access to a patient's access site such as an arteriotomy and can be removed without disturbing the position of the medical device.

A method for measuring a distance in a body vessel and introducing an implant into the body vessel, the method comprising: providing a guide wire, wherein the guide wire comprises a proximal end and a distal end, wherein the distal end comprises a spiral which has at least two adjoining spiral sections as markings, wherein at least a surface of one spiral section comprises a first material and at least a surface of the second spiral section comprises a second material, and further wherein the first material is different than the second material; inserting the guide wire into the body vessel; measuring the distance in the body vessel using the markings on the guide wire; and delivering the implant over the guide wire to the body vessel.

A guide wire is disclosed, the guide wire including a flexible wire main body, a coil that is intermediately disposed in a longitudinal direction of the wire main body in an outer periphery of the wire main body, and a support portion that supports at least one of a distal end and a proximal end of the coil so as to be rotatable around a central axis O of the wire main body. In a natural state where an external force is not supplied to the guide wire, the support portion supports in a state where an inner peripheral portion of the coil and an outer peripheral portion of the wire main body are separated from each other.

A tubular support structure for use in an elongate intravascular medical device comprises an elongate tubular body, a patterned frame structure formed within the elongate tubular body, an inner lumen axially disposed within the elongate tubular body, and a first set of floating tabs axially spaced apart along the patterned frame structure. Each of the first set of floating tabs has a cantilevered end affixed to the patterned frame structure and a free end configured for translating relative to the patterned frame structure and then engaging the patterned frame structure as the tubular support structure is laterally deflected in a first bending direction.