A guidewire includes, for example, a core shaft, a coil body having a distal end that is joined to the core shaft at a position spaced proximally from a distal end of the core shaft, and a coating agent covering an outer periphery of the core shaft and the coil body. The core shaft includes a bulge portion joined at a position spaced distally from the distal end of the coil body, and the coating agent covers the core shaft and the coil body from a distal side of the bulge portion to a proximal side of a proximal end of the coil body except for an interior of the coil body.

An energy delivery guide wire (10) including a guide wire proximal portion (12), a guide wire distal portion (14) and an energy delivery tip (16) extending from the distal portion (14); the energy delivery tip (16) having a tip length, a proximal tip end (18) and a distal tip end (20); at least the guide wire distal portion (14) extending in a first direction in an unbiased condition; the energy delivery tip (16) extending in a second direction different from the first direction; wherein the distal tip end (20) is offset from the proximal tip end (18) relative to the first direction by between 10 to 50 % of the tip length.

The present disclosure relates to guidewire devices with an outer tube and a core. The distal section of the core extends into and is surrounded by the outer tube. One or more centering mechanisms are also disposed within the outer tube and are arranged to fill a portion of the annular space between the core and the inner surface of the tube. The one or more centering mechanisms thereby assist in keeping the distal section of the core axially aligned within the tube, which enables effective control of the device and minimizes undesirable whip movements of the guidewire.

A guide wire that includes a core shaft, a coil wound around the core shaft, a distal-end joining region to which a distal end of the core shaft and a distal end of the coil are joined, and a proximal-end joining region to which a proximal end of the core shaft and a proximal end of the coil are joined, and the coil has a sparsely wound portion having a sparser coil pitch than other portions of the coil, the sparsely wound portion being disposed between the distal-end joining region and the proximal-end joining region.

A delivery guidewire for navigating a catheter in the heart to deliver a valve prosthesis. The delivery guidewire comprising an elongated core, an outer sleeve disposed on the elongated core, and a coil disposed on a distal portion of the elongated core. The delivery guidewire having a first section having a generally uniform diameter and a second section having a tapering section. A distal portion of the second section of the delivery guidewire comprises a pigtail shape atraumatic tip which can remain in the left ventricle.

A catheter that includes a tubular inner layer, a first reinforcing body that is wound around an outside in a radial direction of the inner layer, a second reinforcing body that is wound around the outside in the radial direction of the first reinforcing body, and an outer layer that covers the inner layer, the first reinforcing body, and the second reinforcing body, and the inner layer has a reduced diameter portion that is reduced in diameter from a proximal end side of the catheter toward a distal end side of the catheter on an inner peripheral surface of the inner layer, and a thickness of the outer layer between the first reinforcing body and the second reinforcing body is increased, at least partially from the proximal end side toward the distal end side, in the radial direction of the reduced diameter portion.

The present disclosure relates to interventional devices such as catheters and guidewire devices having micro-fabricated features for providing flexibility while maintaining good torquability. An interventional device includes an elongated member (500) having an arrangement of fenestrations which define a plurality of axially extending beams coupling a plurality of circumferentially extending rings. The fenestrations are arranged so that the resulting beams form a distributed, non-helical and non-linear pattern along the length of the elongated member. The pattern of fenestrations thereby minimizes or eliminates preferred bending axes.

A coil is made by helically winding a wire rod. A cross-sectional shape of the wire rod of the coil includes a curved portion that is arcuately curved toward a center axis of the coil; a flat portion that is provided on an outer circumference of the coil, and is formed in a flat shape with a curvature that is smaller than a curvature of the curved portion; and at least one protruding portion that is provided at the boundary between the curved portion and the flat portion or in the vicinity of the boundary, and protrudes toward an adjacent wire rod.

The disclosure is directed to a targeting guidewire. The guidewire includes a distal portion including four portions and three transition zones between the adjacent portions. A first and a third portions have a smaller stiffness than a second and a fourth portions. The first and the third portions may also have a smaller overall outer diameters than the second and the fourth portions. The three transition zones comprises marking elements so as to delineate their locations.

The present disclosure relates to core-wire joints for micro-fabricated medical devices, such as guidewires. A hybrid guidewire device includes a core (102) having a joint (105) between a proximal section (110) and a distal section (112) of the core and a tube structure (104) surrounding the joint. The proximal section of the core is made of or includes stainless steel and the distal section is made of or includes a superelastic material such as nitinol. Further, the terminal, distal portion of the proximal section of the core includes serrations (116), and a terminal, proximal portion of the distal section of the core includes complementary serrations (118) sized and shaped to interlock with serrations (116). The distal end of the proximal section mechanically interlocks with a proximal end the distal section to form the joint.