Electrical non-invasive brain stimulation (NIBS) delivers weak electrical currents to the brain via electrodes that are affixed to the scalp. NIBS can excite or inhibit the brain in areas that are impacted by that electrical current during and for a short time following stimulation. Electrical NIBS can be used to change brain structure in terms of increasing white matter integrity as measured by diffusion tensor imaging. Together the electrical NIBS can induce changes in brain structure and function. The present methods and devices are adaptable to and configurable for facilitating the enhancement of brain performance, and the treatment of neurological diseases and tissues. The present methods and devices are advantageously designed to utilize modern electrodes deployed with, inter alia, various spatial arrangements, polarities, and current strengths to target brain areas or networks to thereby enhance performance or deliver therapeutic interventions.

Devices and methods for treating dry eye and other ophthalmic conditions are provided. The devices may be configured to be located in a patient's fornix. In one embodiment, a device includes a flexible substrate, an antenna disposed on a first side of the substrate, one or more electronic components disposed on the first side of the substrate, and a first electrode and a second electrode disposed on a second side of the substrate opposite the first side. Each of the first electrode and the second electrode comprises an electrode surface and a plurality of slots in the electrode surface defining a plurality of electrode prongs. The plurality of slots facilitate or promote near-field coupling between a transmitter and the antenna. The one or more electronic components are configured to provide electrical power to the first electrode and the second electrode.

The present invention relates to a method for inducing a controlled fluid transport in a central nervous system, CNS, and/or in a cerebrospinal fluid, CSF system, of a patient by electro-osmosis, EO, via two or more electrodes placed at selected locations on the patients head, comprising receiving EO information, the EO information being at least indicative of fluid transport response resulting from application of particular electric potentials and/or currents at particular electrode locations on the patient's head based on a patient-specific three-dimensional head model, receiving a fluid source location within the patient's head, selecting a set of electrode locations using the EO information and the fluid source location, placing the two or more electrodes in electrical communication with said CNS/CSF-system, each electrode being placed at one location of the selected set of electrode locations, and controlling an application of selected electric potentials and/or electric currents to said electrodes, wherein the selected electric potentials and/or electric currents is selected as electric potentials and/or electric currents associated to the selected set of electrode locations by the EO information, so as to induce a controlled fluid transport in said CNS/CSF-system.

The present invention relates to systems for providing noninvasive cranial nerve stimulation and methods for using the same. The present invention administers therapy through electrodes that are noninvasively attached to one or more of a subject’s cranial nerve. The systems can be used to enhancing rehabilitation and recovery by improving neuroplasticity and coupling muscle training with feedback.

In an embodiment, a sinus treatment apparatus includes a current generation circuit and first and second electrodes operatively coupled to the current generation circuit. The first electrode is configured to apply electric current to a treatment location on a skin surface of the user superjacent to a targeted anatomical structure coupled to the user's sinus. The second electrode is configured to provide a current return path to the current generation circuit from a second location on the surface of the user medial to the user's hand. In an embodiment, a method of using the sinus treatment apparatus includes receiving a return current through the user's body from a location other than the user's palm.

Systems and methods for improving behavioral therapies encompassing therapies wherein a perceptual stimulus is administered to a subject or a motor behavior is performed by the subject. Such administration of perceptual stimuli or motor performance is paired with the delivery of vagus nerve stimulation to the subject. The vagus nerve stimulation is timed with the sensory stimulus administration or motor performance in a temporal alignment that maximizes neuroplasticity and performance. Systems for performance of the method and associated software are also disclosed

Described herein are high-power pulsed electromagnetic field (PEMF) applicator apparatuses. These apparatuses are configured to drive multiple applicators to concurrently deliver high-power PEMF signals to tissue. The apparatuses may be further configured to wirelessly communicate with local computing device and a remote server for patient monitoring, prescription and/or device servicing.

A system, device, and method for transcutaneous nerve stimulation such as facial nerve stimulation, and in particular, to using transcutaneous nerve stimulation for artificially eliciting eye blink, such as with humans with acute facial paralysis (Bell's palsy or Dry Eye syndrome), is disclosed. A battery-operated wearable device may employ a pulse generator for periodically and automatically generating bursts train of asymmetrical Bi-Phasic square pulses. The output pulses are fed to two electrodes that are attached to the skin of the treated person to stimulate the facial nerve for eliciting blinking at a rate that mimics normal blinking operation. The device may include a sensor and a wireless connection, and the parameters of, or the activation of, the generated bursts may be controlled by the sensor output, by human user control, or by data received from the wireless network. Further, the device may transmit status to the wireless network.

A bone conduction apparatus according to the present invention includes: a decoding unit decoding audio data; a digital-to-analog converter converting the decoded audio data to an analog signal, and outputting an analog audio signal; a bone conduction unit converting the analog audio signal to a bone conduction signal, and outputting the bone conduction signal; a metal electrode placed at an outside of a housing in which the bone conduction unit is provided; a frequency generator generating a transcutaneous electrical nerve stimulation (TENS) signal; and a TENS signal amplification unit amplifying the TENS signal, and applying the resulting signal to the metal electrode.

The pain-relieving apparatus has a housing, a stimulating surface, user inputs, and a plurality of ports, such as a battery port and a transcutaneous electrical nerve stimulation (TENS) output connector. The stimulating surface may include a suction ring, vacuum apertures, vibration stimulators, a plate, heat and cold transducer elements, and medicinal holders to provide various approaches for relieving pain. The pain-relieving apparatus may also have a sound speaker for producing nerve stimulating sounds.