Systems, devices and methods are provided for transcutaneously delivering energy impulses to bodily tissues for therapeutic purposes, such as for enhancing the body's bone healing process in spinal fusion patients. A therapeutic stimulator system comprises a housing for an energy source and a signal generator. The system further includes one or more electrodes coupled to the signal generator. A processor is coupled to the housing and configured to determine usage levels of the signal generator and/or motion data of the housing. The system may include a mobile device that allows the patient to input user status data, such as pain levels, and compare the user status data with the usage levels and/or the motion data, thereby improving patient compliance with a prescribed therapy regimen.

Described is a low voltage, pulsed electrical stimulation device for upregulating expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells.

Generally discussed herein are systems, devices, and methods for providing a therapy (e.g., stimulation) and/or data signal using an implantable device. Systems, devices and methods for interacting with (e.g., communicating with, receiving power from) an external device are also provided.

An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.

A shoulder brace includes a shoulder cuff that can be worn to cover the shoulder of a user, an upper arm cuff that can be worn to cover the elbow joint of the user, a belt that can secure the shoulder cuff to the shoulder of the user, and an actuator that is the McKibben artificial muscle which can optionally expand and contract in entire length. The actuator contains a main actuator to link the vicinity of the acromion on the shoulder cuff and a side face of the upper arm cuff across the shoulder joint, an anterior auxiliary actuator to link a front face of the shoulder cuff and a front face of the upper arm cuff across the shoulder joint, and a posterior auxiliary actuator to link a back face of the shoulder cuff and a back face of the upper arm cuff across the shoulder joint.

A system and method for pulsed electromagnetic fields (PEMF) tissue engineering enhances musculoskeletal tissue stimulation. A tissue engineering device may include both low and high pulse frequency signal generation components that may alternatively drive one or more coils to generate PEMFs. These PEMFs may be applied to bone tissue, tendons, ligaments, and/or cartilage. A prescribed treatment regimen using the tissue engineering device may include a first period of time where a first pulse frequency is used in treatment that supports tissue proliferation followed by a second period of time where a second pulse frequency (less than the first pulse frequency) is used in treatment that supports tissue differentiation. A treatment regimen may also include, with the frequency characteristic, applying a slew rate to the pulse characteristics that is on the order of around 30 to 100 Tesla per second to drive tissue differentiation in a targeted manner.

A device and a method for stimulating skin regeneration is described which allows exploiting the combined action of the surface vasculature (given by the action of the vacuum) and of the cellular regeneration (given by the electromagnetic field generated by a capacitive system) combined with the skin electrostimulation applied, in this case, so as to amplify the biological effect of the electromagnetic field.

An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.

A therapeutic apparatus for treating damaged tissue on a limb or body of a subject includes a wearable adapted to cover and be secured to the limb or body of a subject over damaged tissue. The wearable being configured to reduce pressure on the damaged tissue and adapted to deliver one or more treatments selected from the group consisting of heat, oxygen, electrical current, and light to the damaged tissue.

A terminal device includes: a treatment content setting unit that sets a first treatment content performed by a first electrical treatment device and a second treatment content performed by a second electrical treatment device; and a treatment instruction unit that instructs the first electrical treatment device and the second electrical treatment device to treat a user in accordance with the first treatment content and the second treatment content. The treatment content setting unit swaps the first treatment content and the second treatment content in accordance with a preset instruction. The treatment instruction unit, when the first treatment content and the second treatment content are swapped, instructs the first electrical treatment device and the second electrical treatment device to treat the user in accordance with the first treatment content and the second treatment content, which have been swapped.