An electrode can comprise carbon black and one of polydimethylsiloxane (PDMS) or PVA, wherein the carbon black has a weight of between 10% and 50% of a weight of the PDMS or PVA. The electrode can be suitable for bioelectronics. A pattern of hydrogel can be deposited on the electrode for providing adhesion to a subject. The electrode can be used in wound treatment and/or monitoring devices or in various other bioelectronics applications.

Systems and methods for a smart bandage for monitoring and treating wounds are provided herein. The smart bandage may be a smart, wearable, flexible multi-layer substrate that may include a system that can monitor wound characteristics, perform autonomous bioanalysis of wound characteristics to determine wound treatment plans in a non-invasive method, perform drug delivery or antimicrobial agent release to treat and prevent infections, and promote healing by electrical stimulation. The smart bandage may be equipped with a wireless network that can communicate with users, such as patients and medical providers, directly about a patient's wound condition and provide for on-demand wound treatment.

The present invention relates to a method of medical treatment of lameness in a mammal in need thereof, the method comprising applying pulsed radiofrequency (PRF) to the mammal so that an outcome selected from the group consisting of an improvement stance or gait, a stabilization in the decrease of a deviation from normal stance or gait, a decrease of the manifestation of pain, a stabilization in the manifestation of pain, a decrease in the mechanical restrictions causing alteration of stance or gait, a stabilization in the mechanical restrictions causing alteration of stance or gait, a decrease in neuromuscular disease, a stabilization in neuromuscular disease, and/or a decrease or stabilization of inflammation is achieved.

The invention relates to a treatment device for dielectric harrier discharge plasma treatment of a wound surface or skin surface, having: a flexible, planar electrode assembly with at least one planar electrode (6, 6′) and a dielectric layer (5) which at least partially embeds the at least one electrode (6, 6′), has a contact side (7) facing the wound surface or skin surface and electrically shields the planar electrode (6, 6′) from the wound surface or skin surface such that only a dielectric barrier current can flow from the electrode (6, 6′) to the wound surface or skin surface; and a control device (2) which has a separate housing (25) and via which the electrode (6, 6′) can be connected to an operating voltage. The treatment device allows simpler wound treatment in that the assembly of electrode (6, 6′) and dielectric layer (5) is designed for uninterrupted contact with the wound surface or skin surface and that the housing (25) of the control device (2) can be fastened with a fastening device (3, 3′) to the body having the wound surface or skin surface.

The present invention relates to a stimulation electrode comprising an ionically conductive pressure sensitive adhesive composition comprising a) a (meth)acrylate resin comprising at least 10% of a (meth)acrylate monomer comprising OH-group by weight of the total weight of the (meth)acrylate resin; and b) an ionic liquid. The stimulation electrode according to the present invention is used in skin applications transferring an electrical signal to the body via skin.

A reduced pressure treatment system is provided that includes a canister that is fluidly connected to a tissue site and is configured to receive fluid drawn from the tissue site under the influence of a reduced pressure. A reduced pressure source provides the reduced pressure and is fluidly connected to the tissue site by a fluid communication path, which may include a source conduit, the canister, and a target conduit. A sensing device communicates with the source conduit and is configured to sense a pressure in the source conduit. A valve communicates with the source conduit and is configured to vent the reduced pressure. A processing unit communicates with the sensing device and the valve and is configured to open the valve for a selected amount of time, determine a decay of reduced pressure, and determine a fill status of the canister based on the decay of reduced pressure.

A plasma torch having an open end from which a plasma plume is emitted in use is disclosed. The plasma torch includes a central cathode rod, a grounded conductive tube having an open end and being arranged around the cathode and spaced therefrom to form a first cylindrical cavity open at one end; and a high voltage electrode having a dielectric barrier material at a radially inward-facing surface thereof and being arranged around the grounded conductive tube and spaced apart therefrom to form a second annular cylindrical cavity open at one end. A constant direct current (DC) electrical power plus a high voltage pulsed electrical power is provided to the cathode producing an arc discharge in the first cavity between the cathode and grounded tube to generate a central thermal plasma emitted at an open end of the first cylindrical cavity. A high voltage alternating current electrical power or pulsed electrical power is provided to the high voltage electrode producing a dielectric barrier discharge in the second annular cylindrical cavity to generate a non-thermal plasma emitted from an open end of the second cavity as a halo around the central thermal plasma.

Electroceutical dressings having at least three electrodes that are used for prevention and mitigation of biofilm and bacterial infection by an applied electric current are provided. Methods of making the dressings and methods of applying an electric current to promote the wound healing process are also disclosed.

An apparatus for controlled healing of ocular erosions is described. The apparatus comprising; an optical surface comprising an energizable controller capable of being programmed to transmit energy from an energy source onto/into an ocular surface, through the use of a current generator in electrical connection with energy emitting contacts capable of transmitting an electric field. The controller, current generator and energy emitting contacts are biocompatible or encapsulated by a conductive biocompatible layer to allow positioning of said apparatus in an ocular surface.

Disclosed herein are atmospheric pressure pin-to-hole pulsed spark discharge devices and methods for creating plasma. The devices include a conduit for fluidically communicating a gas, a plasma, or both, therethrough, portion of the conduit capable of being connected to a gas supply, and a second portion of the conduit capable of emitting a plasma; a positive electrode comprising a sharp tip; and a ground plate electrode. Disclosed are methods for treating a skin ulcer using non-thermal plasma include flowing a gas through a cold spark discharge zone simultaneously with the creation of a pulsed spark discharge to give rise to a non-thermal plasma emitted from a conduit, the non-thermal plasma comprising NO; and contacting a skin ulcer with said non-thermal plasma for sufficient time and intensity to give rise to treatment of the skin ulcer.