What is provided is a method and apparatus for blocking a pain signal by selectively electrically stimulating a mammalian nerve comprising: applying a dermal patch having an integral electrode in proximity to an A-alpha or A-beta touch sensitive nerve; determining a stimulation corresponding to the A-alpha or A-beta touch sensitive nerve, by logic of the dermal patch; applying the stimulation by the electrodes and a stimulator integral to the dermal patch to produce an electric field; and selectively activating the A-alpha or A-Beta touch sensitive nerve by the electric field.

A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.

Provided is a respiratory abnormality improvement apparatus capable of effectively improving respiratory abnormality during sleep. The present invention is a respiratory abnormality improvement apparatus for applying a stimulus signal generated in a stimulus generating unit to a patient as an electric stimulus. Here, the apparatus includes a respiration detection unit for detecting a respiratory condition of the patient. Particularly, the stimulus generating unit is so configured that a first stimulus signal generated at a current level preset at a given time, and a second stimulus signal of a current level different from that of the first stimulus signal are generated as stimulus signals to an electrode member worn by the patient based on a detection signal from the respiration detection unit when the patient has been judged to be under a respiratory abnormality condition.

A device for the determination of at least one compression parameter during the administration of cardiopulmonary resuscitation (CPR) on a patient. The device includes a compression unit adapted to move in accordance with the chest of a patient and a surface unit adapted to move in accordance with a surface supporting the patient. The compression unit has one of a signal component and reference component, the surface unit has the other of the signal component and the reference component. The device also includes a processor configured to determine a relative measurement between the compression unit and the surface unit using data derived from the signal component and the reference component. The processor is further configured to determine the at least one compression parameter based on the relative measurement. The determined at least one compression parameter takes into account any motion and/or displacement of the surface.

Provided is a patch able to produce micro-current to be applied on human skin including a support for electrodes spaced from each other and apt to create voltages typical of galvanic piles, connection means between the electrodes, an adhesive layer applied on one side of the support and apt to adhere to the skin and a protection liner applied on the adhesive layer, the support being a membrane permeable to the moisture inside the electrodes, and the connection means being defined by a material that is avid of moisture, such as silica impregnating the membrane.

Apparatus and methods are described including electrodes (22) configured to be placed upon a portion of a body of a subject, and a user interface device (26). A computer processor (24) applies a neuromodulation treatment to the subject, by driving electrical pulses into the portion of the subject's body via the electrodes, and generates an output on the user interface device that indicates to the subject a physiological effect that the neuromodulation treatment has upon the subject's body. Other applications are also applied.

Examples of the present disclosure are related to devices in the field of transcutaneous electrical nerve stimulation and neuromuscular electrical stimulation. More specifically, embodiments are related to devices that are configured to automatically detect the stimulation intensity range and the motor point to generate a high efficiency, low intensity electrical stimulation treatment.

The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopathy are provided. For example, the present invention provides materials and methods for modulating glymphatic clearance (e.g., enhancing glymphatic clearance) of pathogenic proteins.

Systems, devices, and methods are provided to assess connection quality between the electrodes of a bioelectrical signal measurement and/or electrical stimulation device and the tissue, typically skin, of the subject. A test signal is provided to a first electrode, voltage differences between the first electrode and additional electrodes are determined, an impedance of the first electrode is determined based on the voltages differences, and the determined impedance indicates connection quality. This process is typically repeated for all of the electrodes to determine connection quality. The user or subject can be alerted if the connection quality is poor, and the bioelectrical signal that is recorded can be provided with data points indicating connection quality during the signal recording.

An envelope is comprised of two sheets of material that are placed one on top of each other with their interior sides facing each other with their edges sealed to each other with an adhesive to form an airtight enclosure. The envelope has at least one medical patch inside it that is attached to the interior side of at least one of the sheets and a layer of medical grade pressure sensitive adhesive surrounding the at least one medical patch. The pressure sensitive adhesive is applied to a part of the surface of the interior side of the sheet in order to attach the sheet of material and the at least one medical patch to the body of a patient. The medical patch can be an electrode for measuring a patient's vital signs or delivering an electric shock or a transdermal patch for delivering a drug to a patient.