An artificial prosthesis is disclosed, which comprises a pixel array, a correlated double sampling unit, an analog-to-digital converter, a digital core, and a digital-to-analog converter. The digital core is configured to perform a calculation of electrical stimulation waveform of each of the pixels by using a processing function of an ANN. As such, the neural stimulation levels for artificial vision can be optimized.

Bioelectronic lens (E-lens) systems for inducing neuroprotective changes in neurons, in particular the retina. A system may include a stimulating electrode configured to be placed on an eye or skin around the eye. The system may further include a return electrode configured such that voltage distribution is focalized to the eye and induced electric fields to an area of interest on the eye or on the skin around the eye are maximized. The electric fields provide neuroprotection and reinnervation.

A stimulating device includes a stimulator for generating electrical signals and an electrode array for transmitting the electrical signals to a target. The electrode array includes a substrate defining an aperture and at least one electrode supported by the substrate. The stimulating device further includes a connector extending from the stimulator and disposed at least partially in the aperture of the substrate to define a space between the connector and the substrate. The connector is configured to establish an electrical connection between the stimulator and the electrode array. A conductive elastic ink is disposed at least partially within the space defined between the connector and the substrate to secure the connector to the substrate.

A pulse current generation circuit (100) for neural stimulation includes an analogue signal receiving device (101) for receiving an analogue signal; an analogue-to-digital converter (102) for converting the analogue signal into a digital control signal; a current signal controller (103) for producing, according to the digital control signal, pulse current parameters for generating bidirectional pulse current signals; and a current generator (104) for generating, according to the pulse current parameters, bidirectional pulse current signals for neural stimulation, and the current generator can generate pulse currents of different precisions according to the pulse current parameters. In addition, the present invention further relates to a charge compensation circuit, a charge compensation method, and an implantable electrical retina stimulator using the pulse current generation circuit or the charge compensation circuit.

One aspect of the invention provides a computer-implemented method of conveying a visual image to a blind subject fitted with a visual prosthesis. The computer-implemented method includes: mapping a representation of a visual image onto a two-dimensional array of points having a resolution greater than or equal to an electrode resolution of the visual prosthesis; identifying one or more continuous paths along the mapped representation; and controlling the visual prosthesis to sequentially actuate electrodes along the one or more paths. Another aspect of the invention provides a system including: a visual prosthesis comprising multiple electrodes; and an imaging processing device in communication with the visual prosthesis. The imaging processing device can be programmed to receive an image and perform any of the methods described herein.

According to an embodiment, a medical device is disclosed. The medical device includes an external unit and an implantable unit. The external unit includes an electronic unit operationally coupled to a transmitter coil that is configured transmit power and/or data signal over a wireless transcutaneous link, a coil unit comprising a loop structure with the transmitter coil being wound around and along at least a part of length of the loop structure, and a fixation unit configured to attach the loop structure to a user's body i) proximal to an implantable receiver coil that is configured to be implanted within a body part, and ii) around a body part of a user such that a part of the body part is positioned in a hollow section of the loop structure. The implantable unit includes the implantable receiver coil configured to receive the power and/or data signal over the wireless transcutaneous link, a processing unit configured to i) process the received data signal to control functionalities of at least one of the components of the implantable unit, and/or ii) utilize the received power for operation of at least one of the components of the implantable unit. The wireless transcutaneous link includes a coupling between the transmitter coil and the receiver coil, and when the loop structure is attached using the fixation unit, at least a substantial number of magnetic field lines generated in response to excitation of the transmitter coil passes through the implantable receiver coil.

Systems and methods for data-compressive sensing in accordance with embodiments of the invention are illustrated. In one embodiment, a sensor array includes an array of sensor circuitries including a sensor and a comparator. Sensor circuitries in the array are connected via wires which form a series of wired-OR circuits. Readouts can be used to measure the signal on the wires and a decoder in communication with the readouts can be used to resolve signals sensed by particular sensors in the array and their locations.

A medical electrical lead includes an insulative lead body extending from a distal region to a proximal region and a conductor disposed within the insulative lead body and extending from the proximal region to the distal region. An electrode is disposed on the insulative lead body and is in electrical contact with the conductor. The medical electrical lead also includes a cross-linked hydrophilic polymer coating disposed over at least a portion of the electrode. The cross-linked hydrophilic polymer coating includes a fibrous matrix comprising a plurality of discrete fibers and pores formed between at least a portion of the fibers and a hydrophilic polyethylene glycol-containing hydrogel network disposed within the pores of the fibrous matrix.

A subretinal prosthetic device includes a substrate provided under a retina, a return electrode for receiving a current such that a ground is formed on the substrate, a plurality of stimulating electrodes provided on the substrate and for generating an active potential to an optic nerve in response to external visual information projected onto the retina, and a switch for controlling the current between each of the plurality of stimulating electrodes and the return electrode. The switch is connected between the plurality of stimulating electrodes and the return electrode to ground the plurality of stimulating electrodes to the return electrode in response to an on or off control signal.

A micro probe array device and method of manufacturing are disclosed. In the micro probe array device, a plurality of working electrodes are arranged in an array form, so that an individual electric signal can be applied to an object for each working electrode. In the micro probe array device, the height of the working electrode may be different, the working electrode and the counter electrode may constitute a double electrode, or the substrate may be made of a flexible material.