This disclosure relates to a device for applying a neural stimulus. A battery supplies electrical energy at a battery voltage and an electrode applies the electrical energy to neural tissue. A circuit measures the nervous response of the tissue and a voltage converter receives the electrical energy from the battery and controls a voltage applied to the electrode based on the measured nervous response of the tissue. This direct voltage control is energy efficient because losses across a typical current mirror are avoided. Further, the control based on the measured nervous response leads to automatic compensation of impedance variation due to in-growth or change in posture. As a result, the stimulation results in a desired neural response.

Sense amplifier circuits particularly useful in sensing neural responses in an Implantable Pulse Generator (IPG) are disclosed. The IPG includes a plurality of electrodes, with one selected as a sensing electrode and another selected as a reference to differentially sense the neural response in a manner that subtracts a common mode voltage (e.g., stimulation artifact) from the measurement. The circuits include a differential amplifier which receives the selected electrodes at its inputs, and comparator circuitries to assess each differential amplifier input to determine whether it is of a magnitude that is consistent with the differential amplifier's input requirements. Based on these determinations, an enable signal is generated which informs whether the output of the differential amplifier validly provides the neural response at any point in time. Further, clamping circuits are connected to the differential amplifier inputs to clamp these inputs in magnitude to prevent the differential amplifier from damage.

An apparatus and method of electrically coupling a previously implanted stimulation lead with a replacement neurostimulator device. The apparatus and method configured to operably couple a proximal portion of a neuromodulation adaptor including a plurality of electrical conductors spaced apart at a first pitch spacing to a corresponding plurality of electrical terminals of a replacement neurostimulator device, and operably couple a distal end of the neuromodulation adaptor including a plurality of conductor elements and an electrically active set screw spaced part of a second pitch spacing to a corresponding plurality of electrical connectors of a previously implanted stimulation lead.

The present disclosure provides advantageous post and partition assembly that is configured and adapted to promote modularity and withstand the harsh environment of central sterile processing processes. Modular post assembly may be removed and relocated on tray without additional fasteners or components. Tray and bracket assembly may further provide identification features to correctly associate cataloged reusable medical devices to identified trays.

A neuro stimulator adapter for a tissue removal device is disclosed. In certain arrangements, the adapter includes an engagement sleeve and a hub. The engagement sleeve is fixedly connected to a portion of the hub. In certain arrangements, the hub further has a contact assembly disposed therein, the contact assembly configured to be connected to an electrical source to deliver neurostimlation to the tissue removal device at a distal end thereof.

Described herein are methods, devices and systems for efficiently storing data for sensed biological signals. A sensed biological signal, or an amplitude and/or filtered version thereof, is provided to an N-bit ADC of an IMD to produce an N-bit data value indicative of an amplitude of the biological signal at a point in time. One of a plurality of chords of a compression curve is selected, based on a magnitude of the N-bit data value, and used to produce an M-bit data value, which is a compressed version of the N-bit data value, wherein M<N. The M-bit data value is stored as an M-bit data slice within memory of the IMD, and can be expanded to a reproduced N-bit data value after being uploaded to a non-implanted device or system.

Systems and methods which provide radial exterior weld terminal configurations for medical device leads are described. A radial exterior weld terminal may comprise an annular conductive structure having a radial exterior weld interface feature, wherein a medical device lead may comprise one or more radial exterior weld terminals. A radial exterior weld interface feature may be disposed at an end of the annular conductive structure and may configure the annular conductive structure to accept a non-axially directed portion of a conductive wire for interfacing a conductor with a weld location on an outer surface of the radial exterior weld terminal. The radial exterior weld interface feature may comprise a truncated aperture configured for the non-axially directed portion of conductive wire to traverse from the inner space to the outer surface. The truncated aperture may comprise a dimple member depressed into the interior space of the annular conductive structure.

A data transmission system for transmitting an electrical data to a nerve cell. A data receiving system for receiving an electrical data from a nerve cell has at least two phototransistor crystals that is stimulated by light to form an electrical signal; an image source that allows the light to be sent to the phototransistor crystals and allows controlling the amount of light transmitted to each phototransistor crystal independently of each other, and at least one control unit that is connected to the image source that controls the amount of light transmitted from the image source to each of the phototransistor crystals.

The present invention provides improved methods for positioning of an implantable lead in a patient with an integrated EMG and stimulation clinician programmer. The integrated clinician programmer is coupled to the implantable lead, wherein the implantable lead comprises at least four electrodes, and to at least one EMG sensing electrode minimally invasively positioned on a skin surface or within the patient. The method comprises delivering a test stimulation at a stimulation amplitude level from the integrated clinician programmer to a nerve tissue of the patient with a principal electrode of the implantable lead. Test stimulations are delivered at a same stimulation amplitude level for a same period of time sequentially to each of the four electrodes of the implantable lead. A stimulation-induced EMG motor response is recorded with the integrated clinician programmer for each test stimulation on each electrode of the implantable lead via the at least one pair of EMG sensing electrodes so as to facilitate initial positioning of the implantable lead at a target stimulation region.

A system for electrical ventilation stimulation of a patient including an implantable nerve stimulator including a stimulation circuit and a pulse generator that produces biphasic charge-balanced pulses to stimulate a phrenic nerve, an external digital programming device having near field communication transmission and a digital interface, and wherein the external digital programming device is used to control settings of the implantable nerve stimulator.