A method of treating a mental disorder of a patient includes generating, by an implantable stimulator configured to be implanted beneath a skin surface of the patient, stimulation sessions at a duty cycle that is less than 0.05 and applying, by the implantable stimulator in accordance with the duty cycle, the stimulation sessions to a tissue location associated with the mental disorder. The duty cycle is a ratio of T3 to T4. Each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes. The implantable stimulator is powered by a primary battery located within the implantable stimulator and having an internal impedance greater than 5 ohms.

One aspect of the present disclosure includes a delivery tool configured to deliver a neurostimulator into a pterygopalatine fossa of a subject. The neurostimulator can include a body connected to an integral stimulation lead having one or more stimulating electrodes. The delivery tool can comprise a handle, an elongated shaft extending from the handle, a hub portion, and a double barrel sheath. The hub portion can be located between the shaft and a spine member that extends axially away from the hub portion. The hub portion can be sized and dimensioned to releasably mate with the neurostimulator. The double barrel sheath can be connected to the spine member. A central lumen can extend through at least a portion of the shaft and the hub portion. The central lumen can be adapted to receive a lead ejector for selective deployment of the stimulation lead from the double barrel sheath.

A leadless pacemaker, a leading component, a trailing component and a delivery device are disclosed. The leading component (10) includes a leading end body (100), a first connection member (101) and a second connection member (102). The trailing component (20) includes a trailing end body (200), a third connection member (203) and a fourth connection member (204). When the leading component (10) is connected to or removed from the trailing component (20), the first connection member (101) is connected to the delivery device (30); the leading component (10) can be axially immobilized by the delivery device, and force is applied to the fourth connection member (204) by the delivery device (30) to enable the second connection member (102) to be connected to or separated from the third connection member (203), so that the leading component (10) and the trailing component (20) of the leadless pacemaker can be connected or separated conveniently; in addition, during performing separation and connection, the leading component (10) can be fixed by the delivery device (30) to prevent the leading component (10) from pulling the heart tissue, thereby making separation and connection safer. When the battery of the leadless pacemaker is exhausted, the connection relationship between the leading component (10) and the heart can be kept unchanged, and the trailing component (20) can be conveniently replaced.

A medical apparatus configured to neuromodulate tissue and/or record patient information is provided. The apparatus includes an external system to transmit transmission signal(s), each signal having at least power or data, and an implantable system to receive the transmission signal(s). The data transfer between the external and implantable systems is asynchronous. The external system includes external antenna(s) to transmit a transmission signal. The transmission signal is an amplitude modulated signal modulated by varying a load on the external antenna(s) that causes an impedance mismatch prior to amplifying the signal for transmission. An implantable device includes implantable antenna(s) to receive the transmission signal. The implantable system comprises a receiver to receive the transmission signal from the implantable antenna(s), implantable transmission module(s) to transmit data to the external system, and a variable load connected to the implantable antenna(s). Data is transmitted by varying the load.

Methods and apparatuses (e.g., devices and systems) for vagus nerve stimulation, including (but not limited to) sub-diaphragmatic vagus nerve stimulation. In particular, the methods and apparatuses described herein may be used to stimulate the posterior sub-diaphragmatic vagus nerve to treat inflammation and/or inflammatory disorders. The implantable microstimulators described herein may be leadless and batteryless.

Systems, devices, and methods are discussed herein for wirelessly transmitting power and/or data to an implanted device, such as an implanted electrostimulator device. In an example, the subject matter includes a layered transmitter device with multiple conductive planes and excitation features. The transmitter device can be tuned to identify and apply device parameters for efficient wireless communication with a deeply implanted device. The transmitter is generally configured for midfield powering applications by providing signals that give rise to propagating signals inside of body tissue.

A method and apparatus generate electrical currents and/or voltage in tissue using particles composed of liquid crystals and magnetic particles.

Various embodiments of a feedthrough header assembly and a device including such assembly are disclosed. The assembly includes a header having an inner surface and an outer surface; a dielectric substrate having a first major surface and a second major surface, where the second major surface of the dielectric substrate is disposed adjacent to the inner surface of the header; and a patterned conductive layer disposed on the first major surface of the dielectric substrate, where the patterned conductive layer includes a first conductive portion and a second conductive portion electrically isolated from the first conductive portion. The assembly further includes a feedthrough pin electrically connected to the second conductive portion of the patterned conductive layer and disposed within a via that extends through the dielectric substrate and the header. The feedthrough pin extends beyond the outer surface of the header.

A system and method for treating anorectal and/or genitourinary dysfunction includes implanting, in a minimally invasive manner, an electro-medical device for stimulation of two or more anatomical or histological structures of the anorectal region and/or genitourinary region. Electrodes operably connected to the device are positioned proximate the target anatomical or histological structures. The device provides either the same or different stimulation algorithms to each anatomical or histological structure, which may be the same or different. The varied stimulation parameters, such as pulse width, pulse amplitude, and pulse frequency, are defined such that after an application of the electrical pulses, an abdominal leak pressure, an abdominal leak volume, or a urine volume increases or a number of incontinent episodes or a mean incontinence volume per episode decreases relative to said parameters prior to the application of the electrical pulses.

An energy harvesting module includes a pendular unit with piezoelectric transducer elastically deformable in bending between a clamped end and a free end coupled to an inertial mass. The piezoelectric transducer includes two coplanar piezoelectric beams arranged side-by-side on either side of a central axis of the transducer, each of the piezoelectric beams including adjacent external and internal arms, arranged side-by-side and formed single-piece. The external arm of each beam has a clamped proximal end and a free distal end, and the internal arm of each beam has a free proximal end supporting the inertial mass, and a free distal end connected to the distal end of the adjacent external arm by a common junction.