An IV catheter device can include or being configured to employ a probe assembly having an integrated fluid flushing mechanism. The probe assembly can be configured in a variety of ways to cause flushing fluid to be injected through a fluid permeable structure of the probe as the probe is advanced distally from a catheter. In this way, the fluid permeable structure can be kept clear of any occlusion that may otherwise form. With the probe extending distally from the catheter, a blood sample may be collected.

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.

The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to receive blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be received from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. In another aspect, the present invention is generally directed to arrangements of skin insertion objects such as microneedles and methods of forming and arranging skin insertion objects. Other aspects of the present invention are directed at other devices for receiving blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.

A bloodletting syringe, including: a hollow needle that can be placed under skins, a barrel connected to the hollow needle, and a pump outlet being connected to the barrel, wherein the pump outlet is a one-way port. When pumping, the pump outlet is opened, air is pumped out of the barrel and hollow needle, when the pumping is stopped, the pump outlet is automatically closed; air pressure in the barrel becomes lower than the pressure outside of the barrel. The bloodletting syringe, bloodletting syringe systems and bloodletting methods of the present invention can be used to remove blood stasis in muscles and tissues safely and with great control by medical staff.

Provided is a puncture needle that receives lower puncture resistance than conventional techniques. A puncture needle in accordance with an aspect of the present invention includes a needle body (10) that includes a main portion (12) and a distal portion (11) tapering from the main portion (12) and that is rotatable about a central axis (1) of the needle body (10), the needle body (10) including needle parts (15) separated by a boundary along the central axis, each of the needle parts (15) being independently translatable along the central axis (1).

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.