An improved disposable puncture depth adjustable safety lancet includes a shell, a lancet core, a spring, and a trigger. The shell has an adjusting ring at a front end thereof to adjust a puncture depth, the adjusting ring being sleeved and clearance-fit at an outside of the trigger head. The adjusting ring and the shell are rotationally connected in a peripheral direction and are fixedly connected in an axial direction, and a rotational locating structure is formed by the adjusting ring and the shell in the peripheral direction. The adjusting ring has an inner wall equipped with a rotating step face or rotating bevel, and rotating the adjusting ring locates the adjusting ring in different locating positions. The rotating step face or rotating bevel is configured to meet the collision face of the lancet core in different axial positions, thereby changing the puncture depth of needle tip.

A sampling element (110) for generating a sample of a body fluid is disclosed. The sampling element (110) comprises a housing (114), the) housing having a chamber (122) with at least one puncture element (112) stored therein. A tip (132) of the puncture element (112) is movable through at least one puncture opening (124) of the housing (114) in order to perforate a skin portion of a user. The sampling element (110) further comprises at least one compression element (150), which is adapted to increase a pressure of the body fluid within a body tissue of the user in a region of puncturing when pressed onto the skin portion of the user. The compression element (150) is movably mounted to the housing (114). The sampling element (110) comprises at least one locking mechanism (168) for releasably locking the compression element (150) in at least two positions. The at least two positions comprise a first position (170) and a second position (172), the second position (172) being offset from the first position (170). In a further aspect of the invention, an analytical device (204) is disclosed, the analytical device (204) being adapted for using the sampling element (110) of the invention.

The present application concerns a system for the withdrawal of body fluids comprising a coupled tensioning and triggering mechanism, wherein the triggering mechanism is mechanically coupled to the tensioning mechanism in such a manner that the puncturing process is automatically triggered by successive continuation of the tensioning movement when the tensioning mechanism is actuated and wherein the lancing process triggered in this manner is carried out by a lancet.

A lancing device with rear adjustment of penetration depth includes a cap, cap holder, ejection pin and shell, wherein: the lancing device has an external and medium depth adjusting sleeve. The ejection pin is located in the medium sleeve and the external depth adjusting sleeve is sleeved outside the medium sleeve; the external sleeve connects axially and circumferentially to the shell, and a rotary locating mechanism is between the external sleeve and the shell; the medium sleeve is connected circumferentially and axially in a sliding way, and a rotary moving mechanism is between the medium the external sleeve, and the medium includes a passive impact face relative to the active impact face of the ejection pin; the external sleeve includes a manual adjusting ring outside the lancing device at the middle and rear part, and rotates to drive the medium sleeve to move axially, changing the needle tip penetration depth.

A sampling element (110) for generating a sample of a body fluid is disclosed. The sampling element (110) comprises a housing (114), the housing having a chamber (122) with at least one puncture element (112) stored therein. A tip (132) of the puncture element (112) is movable through at least one puncture opening (124) of the housing (114) in order to perforate a skin portion of a user. The sampling element (110) further comprises at least one compression element (150), which is adapted to increase a pressure of the body fluid within a body tissue of the user in a region of puncturing when pressed onto the skin portion of the user. The compression element (150) is movably mounted to the housing (114). The sampling element (110) comprises at least one locking mechanism (168) for releasably locking the compression element (150) in at least two positions. The at least two positions comprise a first position (170) and a second position (172), the second position (172) being offset from the first position (170). In a further aspect of the invention, an analytical device (204) is disclosed, the analytical device (204) being adapted for using the sampling element (110) of the invention.

An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator operatively associated with the skin-penetration member, and an analyte quantification member in fluid communication with the inner lumen of the skin-penetration member. Integrated devices including such arrangements are also described.

A single use lancing device comprising: a housing (10) defining a cavity; a needle assembly (12) comprising a needle (50) and a needle holder (52) and located within the cavity; a release member (16); and a spring (14) arranged to bias the needle assembly in a forward direction relative to the release member; wherein the release member comprises retaining arms (38) and is movable relative to the housing between a primed position in which the retaining arms are arranged to cooperate with the housing to restrain the needle assembly in a primed position, and a deployed position in which the restraining arms are arranged to release the needle assembly to deploy the needle.

A handheld lancing device having anesthetic feature includes a housing removably retaining a disposable lancet. A carriage suspended within the housing by an isolation assembly may receive the lancet. A motor in mechanical communication with the lancet produces vibrations transmitted to contact surface, which vibrate a target lancing site prior to and during piercing. The target site is vibrated for a predetermined period of time before deploying the lancet. The isolation assembly permits movement of the carriage and/or lancet within the housing in one direction while limiting movement in other directions, and further dampens the vibrations of the motor from the housing held by the user. A force sensor detects force applied by the pressing of the contact surface against the skin of the patient. An indicator(s) perceivable to the user identifies when predefined positions of the lancet are reached for initiating vibration then triggering the lancet.

Devices and methods for withdrawing bodily fluid from a patient are disclosed herein. A handheld device configured in accordance with the present technology can include a housing having an opening, a skin-piercing assembly located at least partially within the housing, and an actuator movable relative to the housing along a deployment direction. The skin-piercing assembly can include a skin-piercing feature and a biasing member. The biasing member can be coupled to the skin-piercing feature to bias the skin-piercing feature along the deployment direction. Movement of the actuator along the deployment direction to a predetermined position can increase a load on the biasing member to at least a partially loaded state. Movement of the actuator along the deployment direction beyond the predetermined position can release the load on the biasing member so that the biasing member actively drives the skin-piercing feature along the deployment direction.

A microneedle (100) for extracting a blood sample from the skin (10) of a mammal subject is disclosed. The microneedle comprises at least one substantially flat blade (110) comprising at least one cutting edge (120a, 120b) configured to incise the skin of the mammal subject, and at least one microchannel (130) comprising an opening (132) and a passage (134). The at least one microchannel is arranged adjacent to the at least one blade and configured to be inserted into the skin of the mammal subject together with the at least one blade. The passage is configured to transport the blood sample away from the opening via capillary action. A device (200) for extracting a blood sample from a mammal subject comprising a microneedle is also disclosed.