An electric signal transmission device including an electrode 11, disposed to be opposed to an electrogenic cell, and for sending and receiving electric signals to and from the electrogenic cell via the electrode 11.

A medical device is configured to sense an electrical signal and determine that signal to noise criteria are met based on electrical signal segments stored in response to sensed electrophysiological events. The medical device is configured to determine an increased gain signal segment from one of the stored electrical signal segments in response to determining that the signal to noise criteria are met. The medical device determines a noise metric from the increased gain signal segment. The stored electrical signal segment associated with the increased gain signal segment may be classified as a noise segment in response to the noise metric meeting noise detection criteria.

A medical device is configured to sense an electrical signal and determine that signal to noise criteria are met based on electrical signal segments stored in response to sensed electrophysiological events. The medical device is configured to determine an increased gain signal segment from one of the stored electrical signal segments in response to determining that the signal to noise criteria are met. The medical device determines a noise metric from the increased gain signal segment. The stored electrical signal segment associated with the increased gain signal segment may be classified as a noise segment in response to the noise metric meeting noise detection criteria.

When inserting a catheter or other medical equipment into a child or adolescent or other paediatric patient, ECG signals may be recorded from the catheter and the location of the catheter determined by analysing the ECG signals. A signal processor and user interface may receive recorded signals in real-time from the catheter while the catheter is inserted into the paediatric patient. The signal processor may analyse the ECG signals to determine the location of the catheter in the paediatric patient. The user interface may display the location of the catheter and other pertinent information to a user while the user is inserting the catheter. One method for determining the location may include determining R-wave and P-wave peaks of the ECG signal and determining the location from an average location of the R-wave and P-wave peaks in the ECG signal.

When inserting a catheter or other medical equipment into a child or adolescent or other paediatric patient, ECG signals may be recorded from the catheter and the location of the catheter determined by analysing the ECG signals. A signal processor and user interface may receive recorded signals in real-time from the catheter while the catheter is inserted into the paediatric patient. The signal processor may analyse the ECG signals to determine the location of the catheter in the paediatric patient. The user interface may display the location of the catheter and other pertinent information to a user while the user is inserting the catheter. One method for determining the location may include determining R-wave and P-wave peaks of the ECG signal and determining the location from an average location of the R-wave and P-wave peaks in the ECG signal.

A method for heart failure management may include volume overload intervention in response to sensor-based parameters indicating volume overload. The method may include administering non-volume overload intervention in response to the sensor-based parameters not indicating volume overload. Volume overload may be determined based on monitoring sensor-based parameters. Sensor-based parameters may be monitored in response to receiving an alert indicative of a worsening heart failure score or status for a patient.

Computer implemented methods and implantable medical devices (IMD) are provided that obtain cardiac activity (CA) signals for a cardiac beat and compare the CA signals to a sensitivity level to detect a sensed event. One or more processors are configured to change the sensitivity level, utilized by the sensing circuitry, over the cardiac beat based on an adaptive sensitivity profile. The adaptive sensitivity profile has a maximum sensitivity limit (MSL). The process determines whether a characteristic of interest (COI) from a candidate event satisfies criteria relative to the COI for a collection of prior sensed events, declares the candidate event to be a valid sensed event or a false sensed event based on the determine operation; and adjusts the maximum sensitivity limit based on when the COI from the candidate event satisfies the criteria to provide adaptive sensing of CA signals.

Computer implemented methods and implantable medical devices (IMD) are provided that obtain cardiac activity (CA) signals for a cardiac beat and compare the CA signals to a sensitivity level to detect a sensed event. One or more processors are configured to change the sensitivity level, utilized by the sensing circuitry, over the cardiac beat based on an adaptive sensitivity profile. The adaptive sensitivity profile has a maximum sensitivity limit (MSL). The process determines whether a characteristic of interest (COI) from a candidate event satisfies criteria relative to the COI for a collection of prior sensed events, declares the candidate event to be a valid sensed event or a false sensed event based on the determine operation; and adjusts the maximum sensitivity limit based on when the COI from the candidate event satisfies the criteria to provide adaptive sensing of CA signals.

An example fixation component for an implantable medical device (IMD) includes a base and tines extending from the base and being spaced apart from one another. The tines include a penetrator tine and a protector tine. The penetrator tine includes a curved section defining a deformable preset curvature that extends laterally from a proximal section that is fixed to the base, traversing a longitudinal axis of the fixation component, to a distal section that terminates in an incisive distal end that is configured to penetrate a tissue to form a puncture. The protector tine includes a curved section defining a deformable preset curvature that extends from a proximal section that is fixed to the base, outward from the longitudinal axis, to a distal section that terminates in a non-incisive distal end that is configured to pass through the puncture.

Example electronic devices, including but not limited to implantable medical devices, and methods employing dynamic announcing for creation of wireless communication connections are disclosed herein. In an example, an electronic device includes a wireless communication interface to transmit announcement signals for creating a wireless communication connection with the external device. The electronic device also includes a sensor to detect a characteristic of an environment external to the electronic device, and a control circuit including an announcement timing control module to dynamically control timing of the announcement signals based on the detected characteristic.