The present invention is directed to a wearable system wherein elements of the system, including various sensors adapted to detect biometric and other data and/or to deliver drugs, are positioned proximal to, on the ear or in the ear canal of a person. In embodiments of the invention, elements of the system are positioned on the ear or in the ear canal for extended periods of time. For example, an element of the system may be positioned on the tympanic membrane of a user and left there overnight, for multiple days, months, or years. Because of the position and longevity of the system elements in the ear canal, the present invention has many advantages over prior wearable biometric and drug delivery devices.

An obstructive sleep apnea detection device including an optical engagement surface adapted to engage a user's skin; a light source adapted to emit light from the optical engagement surface; a photodetector adapted to detect light at the optical engagement surface and to generate a detected light signal; a position sensor adapted to determine patient sleeping position; a controller adapted to determine and record in memory blood oxygen saturation values computed from the detected light signal and user position information from the position sensor; and a housing supporting the optical engagement surface, the photodetector, the light source, the position sensor, and the controller.

An earpiece having light sources and optical sensors arranged to obtain physiological data from the tragus of an ear. At least one extra light source or optical sensor is provided such that there is redundancy. The redundancy allows for misalignment of the earpiece while still having sufficient number of light sources and optical sensors to continuously obtaining physiological data.

A system for determining a direction of gaze of a user, comprising a set of electrodes arranged on earpieces, each electrode comprising a patch of compressible and electrically conducting foam material. The system further includes circuitry connected to the electrodes and configured to receive a set of voltage signals from a set of electrodes arranged on an audio endpoint worn by a user, multiplex said voltage signals into an input signal, remove a predicted central voltage from said input signal, to provide a detrended signal, and determine said gaze direction based on said detrended signal. Such conducting foam materials provide satisfactory bio-sensing performance for a wide range of compression levels and over time. In the case of on-ear headphones, the foam electrodes may be integrated in the cuffs with little or no effect on the comfort level.

An in-ear hearing device includes a light source configured to emit light, a photodetector configured to detect the emitted light after the emitted light passes through tissue of a subject, a spout; an audio receiver configured to deliver a sound to the subject through the spout, and a dome configured to conform to a shape of a subject's ear canal when the hearing device is in the ear canal. An output of the light source and an input of the photodetector are separated by the dome, and the dome absorbs and/or reflects at least part of the emitted light. The photodetector may be a forward biased photodiode. The sensor device can be realized with power levels, circuitry components, and in package sizes, of hearing devices.

The present invention relates in particular to the field of anesthesia and to a method for real-time evaluation of the mean arterial pressure of a patient from plethysmography measurements. It also relates to a method for treating a patient comprising by continuously evaluating the mean arterial pressure of the patient, based on values continuously calculated by plethysmography.

A sensor cover according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor, such as a pulse oximetry sensor. Certain embodiments of the sensor cover reduce or eliminate false readings from the sensor when the sensor is not in use, for example, by blocking a light detecting component of a pulse oximeter sensor when the pulse oximeter sensor is active but not in use. Further, embodiments of the sensor cover can prevent damage to the sensor. Additionally, embodiments of the sensor cover prevent contamination of the sensor.

Systems and methods for non-invasive blood pressure measurement are disclosed. In some embodiments, a system comprises a wearable member configured to generate first and second signals, and a blood pressure calculation system. The blood pressure calculation system a pre-processing module configured to filter noise from the signals, and a wave selection module configured to identify subsets of waves of the signals, a feature extraction module configured to generate sets of feature vectors form the subsets of waves, and a blood pressure processing module configured to calculate an arterial blood pressure value based on the sets of feature vectors and an empirical blood pressure calculation model, the empirical blood pressure calculation model configured to receive the sets of feature vectors as input values. The blood pressure calculation system further includes a communication module configured to provide a message including or being based on the arterial blood pressure value.

An eco-system for tracking a user's physiological parameters comprises a central sensor and at least one remote sensor in wireless communication with the central sensor, a portable device readily accessible to the user, and a cloud platform. Each sensor may be worn by the user and measure data indicative of one or more of the physiological parameters. The central sensor may receive and process the measured data from each remote sensor and processes its own measured data. The portable device comprises a receiver wirelessly receiving the processed data and instructions from the central sensor; a processor running a mobile application handling the processed data and instructions; and a transmitter transmitting the processed data. The cloud platform receives the processed data from the transmitter; analyzes the received processed data; and transmits the results of the analysis to at least one of the portable device and an authorized healthcare entity.

A neural analysis system, including: a neural event extractor for generating Sp/Ap curve data and field potential data for background and initial response segments obtained from a person; a correlator for correlating the Sp/Ap curve data and field potential data with pathology data for a condition, and generating biomarker data points for axes of a biomarker display; and a display module for providing display data to generate the display with the points for use in assessing the person relative to the condition.