A total knee replacement, comprising a femoral and a tibial component in articulating contact that can restore normal joint function. The articulation between the two components is controlled by four guide surfaces.

An implant for repairing an articular cartilage defect site including an implant fixation portion with an upper segment and at least one bone interfacing segment and a top articulating portion with an articulating surface and an engagement surface. The upper segment includes a supporting plate with a first locking mechanism segment. The engagement surface includes a second locking mechanism segment. The first locking mechanism segment with at least two channels is structured to couple to the second locking mechanism segment with at least two protrusions. The at least one bone interfacing segment structured for insertion into the articular cartilage defect site. An implant including an implant fixation portion, a top articulating portion, and a locking mechanism with a first locking segment coupled to the upper segment and a second locking segment coupled to the at least one engagement surface and structured to couple to the first locking segment.

According to some embodiments, a method of treating a joint of a patient comprises creating a recess in a bone located at or near a targeted joint, wherein the recess includes a generally wedge or truncated cone shape. In one embodiment, the recess in a bone comprises a surface opening along an outer surface of the bone and a bottom opening along the distal end of the recess, such that a diameter of the surface opening is generally smaller than a diameter of the bottom opening. The method additionally comprises providing a joint implant having a wedge or truncated cone shape, wherein a diameter of a top end of the joint implant is generally smaller than a diameter of a bottom end of the joint implant, inserting the joint implant within the recess.

An endoluminal prosthesis system deployable in a region of a patient's vasculature having one or more branch vessels, having a main graft body having a first opening in a wall portion of the main graft body and a pre-loaded guidewire positioned inside the main graft body and advanced through the first opening. One or more branch grafts can be attached to the main graft body to cover one or more openings in the main graft body.

An expandable spacer, comprising: an axial tube having a surface, a proximal end and a distal end and a length, wherein, said surface defines a plurality of slits, said plurality of slits defining at least two axially displaced extensions, such that when said tube is axially compressed, said extensions extend out of said surface and define a geometry of an expanded spacer. Preferably the spacer is adapted to be inserted between two spinal vertebrae of a human.

Bone anchor implants, assemblies, systems, instruments, and methods thereof. The bone anchors may be threaded or non-threaded, adjustable or expandable, stackable, or otherwise configured to promote fixation of the sacroiliac joint. The bone anchors may be used independently or may be configured to integrate with long rod constructs, for example, with a tulip or other suitable attachment interface, to fuse the sacroiliac joint.

Bone anchor implants, assemblies, systems, instruments, and methods thereof. The bone anchors may be threaded or non-threaded, adjustable or expandable, stackable, or otherwise configured to promote fixation of the sacroiliac joint. The bone anchors may be used independently or may be configured to integrate with long rod constructs, for example, with a tulip or other suitable attachment interface, to fuse the sacroiliac joint.

This invention improves upon prior art total disc replacements (TDRs) by more closely replicating the kinematics of a natural disc. The preferred embodiments feature two or more fixed centers of rotation (CORs) and an optional variable COR (VCOR) as the artificial disk replacement (ADR) translates from a fixed posterior COR that lies posterior to the COR of the TDR to facilitate normal disc motion. The use of two or more CORs allows more flexion and more extension than permitted by the facet joints and the artificial facet (AF). AF joint-like components may also be incorporated into the design to restrict excessive translation, rotation, and/or lateral bending.

A knee prosthesis comprising a femur component defining a ball-like femoral condyle and a tibia component defining a cavity on its medial side corresponding to the ball-like condyle. The knee prosthesis enables pivoting of the tibia component about the medial side of the femur component as a function of the flexion angle as long as there is joint compression applied to the knee prosthesis as exemplified by muscle forces, weight, and ligament tensions, to enforce contact between the tibia component and the femur component. The geometries of the spherical load bearing surfaces of the medial tibia condyle and medial femur condyle provide the kinematic degrees of freedom and the geometric constraints required for proper guiding of the rolling and sliding surfaces of the femoral component and tibial component during articulation of the present knee prosthesis.

The present disclosure discloses an artificial femoral prosthesis (100) for knee arthroplasty, a tibial prosthesis (150), a medial femoral unicompartmental prosthesis (201), a lateral femoral unicompartmental prosthesis (301), and a femoral trochlear prosthesis (401). The femoral prosthesis (100) comprises: a medial condyle portion (51) and a medial trochlear portion (131), wherein an articular surface of the medial condyle portion appears in a sagittal section as an arc of a first ellipse (38), and an articular surface of the medial trochlear portion appears in the sagittal section as an arc of a second ellipse or circle (40); and lateral members (91, 141), comprising a lateral trochlear portion (141) and a lateral condyle portion (91), wherein an articular surface of the lateral trochlear portion appears in the sagittal section as an arc of a third ellipse or circle (80), and an articular surface of the lateral condyle portion appears in the sagittal section as an arc of a fourth ellipse (78). The prostheses according to the above embodiments of the present disclosure can better conform to geometric shapes of normal femoral condyles of humans, thereby simplifying greatly design of parameter values for different models of femoral prostheses.