Patent classifications
A61K8/492
COMPOSITION
The present invention relates to a composition containing (A) a compound represented by the following general formula (1) or a salt thereof:
##STR00001##
[two R.sup.1's each independently represent a hydroxy group or an acetoxy group; R.sup.2 represents a hydrogen atom or —COOR (R is a hydrogen atom, a methyl group, or an ethyl group); and R.sup.3 is a hydrogen atom, an acetyl group, or a methyl or ethyl group]; and (B) a cationic surfactant, wherein the content of the component (B) is 0.25 equivalents or more and less than 2 equivalents relative to the component (A).
PHARMACEUTICAL COMPOSITION AND THE USE THEREOF
A pharmaceutical composition, as well as the use of composition in medical applications, are described.
Gamma-diketones for treatment and prevention of aging skin and wrinkles
The present disclosure relates to compounds, cosmetic or dermopharmaceutical compositions comprising the same, and methods for using the compounds or compositions for treating, protecting, and/or improving the condition and/or aesthetic appearance of skin, for example, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, or improving the appearance of fine lines and/or or wrinkles of skin comprising application of the compounds or compositions disclosed. In some embodiments, the compounds useful in the methods described herein include compounds of Formula I: ##STR00001##
or a dermatologically acceptable salt thereof.
Oral Composition for Tooth Whitening
A tooth whitening oral care composition is made by combining ingredients comprising flakes of a water soluble whitening film, a dye with a hue angle in the CIELAB system ranging from 200 to 320 degrees, and an orally acceptable carrier vehicle. The flakes of the water soluble whitening film comprise: (a) a film-forming polymer comprising hydroxyalkyl cellulose wherein the hydroxyalkyl cellulose has a viscosity of about 1 to about 1000 millipascal seconds (mPa.Math.s) as determined as a 2% by in the CIELAB system ranging from 200 to 320 degrees.
METHOD FOR TREATING AND COLORING HAIR COMPRISING UN-PIGMENTED HAIR
Described herein is a method for treating and coloring hair including un-pigmented hair. The method includes (a) providing a first composition including one or more heavy metal ion sequestrants; (b) applying the first composition to the hair; (c) providing a second composition including one or more weak acids having a pKa from 2.5 to 5; (d) applying the second composition to the hair; (e) providing a third composition including one or more direct dyes chosen from nitro dye, disperse dye, cationic dye, acid dye, basic dye, neutral azo dye and mixtures thereof, and (f) applying the third composition to the hair. The third composition is able to decrease the reflectance of un-pigmented hair in a wavelength range from 530 nm to 670 nm.
Composition Comprising Resveratrol And Melatonin For Reducing Hair Loss And/Or Increasing Hair Regrowth
The invention relates to a composition comprising 0.01% to 15% resveratrol and 0.01% to 15% of melatonin. In a preferred embodiment, the composition comprises 5% resveratrol and 0.1% melatonin. The invention also relates to the use of the said composition to reduce hair loss and/or increase regrowth of hair in a human subject.
Hair cosmetic
The present invention relates to a hair cosmetic containing the following components (A) to (C): (A) a compound represented by the following general formula (1) or a salt thereof: ##STR00001## wherein a broken line represents the presence or absence of a π bond; R.sup.1 represents a hydroxy group or an acetoxy group; R.sup.2 represents a hydrogen atom or —COOR (R is a hydrogen atom, a methyl group, or an ethyl group); and R.sup.3 represents a hydrogen atom, an acetyl group, a methyl group, or an ethyl group; (B) a cationic polymer; and (C) an ampholytic polymer having a predetermined cationic structural unit and an anionic structural unit, a mass ratio of the component (C) to the component (A) [(C)/(A)] being 0.7 or more and 10 or less.
LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF
The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.
MALASSEZIN AND ANALOGS THEREOF AS SKIN BRIGHTENING AGENTS
The present invention relates to compounds, compositions, and methods for brightening skin. The compounds, compositions, and methods of the present invention generally involve compounds produced by a Malassezia yeast, and chemical analogs thereof. In addition to skin brightening applications, the compounds, compositions, and methods of the present invention may be used to modulate melanocyte activity, induce melanocyte apoptosis, agonize an arylhydrocarbon receptor (AhR), improve hyperpigmentation caused by a hyperpigmentation disorder, and modulate melanin production, melanosome biogenesis, and melanosome transfer.
COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID
The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and/or atopy without concern about side effects.