A blood treatment filter including: a filter container that introduces blood from an inlet into an internal space, and discharges treated blood from an outlet; a filter material that is housed in the filter container to partition the internal space into an inlet side space and an outlet side space, and filters the passing blood to remove a specific component; an inlet port that forms an inlet channel through which the blood flowing from the inlet to the internal space passes; an outlet port that forms an outlet channel through which the blood flowing from the internal space to the outlet passes, wherein the outlet channel has a tapered outlet passage with an inner diameter increasing from the internal space side toward the outlet side.

A biological component separation device includes a device main body which is formed of a soft material in a sheet-like shape and in which a filter accommodating unit is provided, a filter member, an introduction port member, and a lead-out port member. An introduction line and a lead-out line are provided in the device main body. In a state in which the device main body is suspended by an introduction tube, a filter accommodating unit inlet where the filter accommodating unit and the introduction line are connected is positioned lower than a filter accommodating unit outlet where the filter accommodating unit and the lead-out line are connected.

Filter assemblies are processing biological fluid, such as blood or a blood component containing leukocytes. The filter assemblies include a flexible housing with first and second walls. A filtration medium and a support member are at least partially positioned between the walls of the housing, with a seal joining the walls of the housing, the filtration medium, and the support member. The filter assemblies may further include a pre-filter and/or a post-filter positioned between the walls of the housing. If provided, the pre- and post-filter may be positioned on opposite walls of the filtration medium, with the post-filter being a mesh positioned between the filtration medium and one of the walls of the housing or within an opening defined by the support member. A seal of the filter assembly may pass through the filtration medium, with the filtration medium being substantially omitted in a section of the seal.

Flexible housing filters for filtration of fluids and methods of making such filters are disclosed. The filters may include one or more peripheral seals in the flexible housing.

Filter assemblies are processing biological fluid, such as blood or a blood component containing leukocytes. The filter assemblies include a flexible housing with first and second walls. A filtration medium and a support member are at least partially positioned between the walls of the housing, with a seal joining the walls of the housing, the filtration medium, and the support member. The filter assemblies may further include a pre-filter and/or a post-filter positioned between the walls of the housing. If provided, the pre- and post-filter may be positioned on opposite walls of the filtration medium, with the post-filter being a mesh positioned between the filtration medium and one of the walls of the housing or within an opening defined by the support member. A seal of the filter assembly may pass through the filtration medium, with the filtration medium being substantially omitted in a section of the seal.

A method for manufacturing a plurality of filter assemblies is provided that includes providing first and second housing sheets and positioning a filtration medium therebetween. Heat and pressure are applied to form first, second, and peripheral seals of at least two filter assemblies at the same time. Each second seal is positioned outboard of the associated first seal with a non-seal area therebetween, while each peripheral seal is positioned outboard of the associated second seal. The first seal commingles the housing sheets and the filtration medium, while the peripheral seal and the periphery of the second seal commingle only the housing sheets. The peripheral seal may include a tear seal to enable separation of a plurality of adjacent filter assemblies.

A biological component separation device (10) includes a device main body (12) which is formed of a soft material in a sheet-like shape and in which a filter accommodating unit (24) is provided, a filter member (16), an introduction port member (14a), and a lead-out port member (14b). An introduction line (26) and a lead-out line (28) are provided in the device main body (12). In a state in which the device main body (12) is suspended by an introduction tube (100), a filter accommodating unit inlet (30) where the filter accommodating unit (24) and the introduction line (26) are connected is positioned lower than a filter accommodating unit outlet (32) where the filter accommodating unit (24) and the lead-out line (28) are connected.

A blood treatment filter comprising a filter element, an inlet-side flexible container and an outlet-side flexible container, an inlet port, and a tubular outlet port, further comprises: an outlet-side frame sheet disposed between the filter element and the outlet-side flexible container; a first seal portion provided by sealing at least the filter element and the outlet-side frame sheet in a belt-shaped manner; and an annular second seal portion provided to surround the first seal portion, wherein on an outlet side of the filter element, a valley portion is fanned at the first seal portion, the outlet port includes a protruding portion that protrudes to an inside of the container, and the protruding portion is provided with an opening at least a part of which overlaps with the first seal portion and which can communicate with a gap region formed by the valley portion.

The invention relates to a filtration unit for the leucocytapheresis of the blood or of a blood product. The filtration unit has an external pouch with at least one inlet orifice and with at least one outlet orifice. the external pouch contains a porous element interposed between the orifices. The porous element has at least one leucocytapheresis medium that works by adsorbing and/or by filtering out the leucocytes, and at least one nonwoven layer provided with bumps, each of the bumps having a perforation passing through it in the heightwise direction.

Disclosed is a blood filtration system including a first blood storage bag, a second blood storage bag, a first pipeline, a filter and a second pipeline. The first blood storage bag is used to store blood. The first pipeline is connected between the first blood storage bag and the second blood storage bag. The filter is configured on the first pipeline. The filter is suitable for blood to pass through via the first pipeline from the first blood storage bag to the second blood storage bag. The second pipeline is connected between the first blood storage bag and the second blood storage bag. The second pipeline is suitable for air in the second blood storage bag to pass through to reach the first blood storage bag.