Wearable auto-injector devices, systems and methods prevent medication administration in a device-worn state using a mechanism that prevents administration medication or by making it impossible or operationally impractical to physical orient or align the device to achieve injection. The device includes a housing, an attachment component enabling the housing to be worn by a user, and a medication delivery system including a needle and a medication reservoir. An advancement system advances the needle into a user's skin and causes the medication to flow through the needle. Various advancement systems, error-reduction mechanisms, attachment alternatives, and optional monitoring and communications capabilities are disclosed.

The present disclosure relates to a cap assembly for a medicament delivery device comprising a cap body configured to be detachably mounted to a housing of a medicament delivery device, and a cap lid configured to be attached to the cap body, wherein the cap body is configured to receive a needle sleeve and the cap lid when the cap assembly is attached to a medicament delivery device, the cap lid comprising an anti-recapping element configured to prevent the cap assembly from being reattached to a housing of a medicament delivery device once the cap assembly has been removed and the medicament delivery device has been used, wherein the anti-recapping element comprises a projection configured to engage a needle sleeve of a medicament delivery device to prevent the cap assembly being reattached to a housing of a medicament delivery device once the medicament delivery device has been used.

In an aspect, the present invention is directed to a ball lock assembly comprising a retention pin for use with an injection device. The ball lock assembly includes a ball lock frame and a ball lock core housed within the ball lock frame that includes a longitudinal opening within which a portion of the pin is positioned. In other aspect, the present invention is directed to an injection device that includes the ball lock assembly of the present invention and a method of using the same.

A method and assembly are disclosed for interfacing between a drug cartridge and a drug delivery device. Optionally, the drug delivery device includes a compartment that retains the cartridge during drug delivery and/or a stopper pushing assembly mounted to the device behind (proximal to) the compartment. In some embodiments, the cartridge may be inserted laterally into the compartment in front of the pushing assembly. For example, the delivery device may include a moving cartridge bay. The cartridge is optionally inserted into the bay and/or the bay and cartridge optionally move into the cartridge compartment. Alternatively or additionally, the cartridge compartment may have a proximal opening into which the cartridge is inserted and/or the pushing assembly may be moved into position after insertion of the cartridge. In some embodiments the cartridge may have a distal seal that is broken by a longitudinal movement.

A medical injection system comprising: a syringe provided with a barrel, a stopper and an injection needle; a plunger rod which engages with the stopper; an injection lock preventing relative movement of the plunger rod with respect to the barrel; and a needle guard comprising a trigger portion and configured to slidably engage the barrel so as to define a first position covering the injection needle and a second position not covering a predetermined portion of the injection needle. The trigger portion is adapted to disengage the injection lock from the plunger rod when the needle guard moves from the first position to the second position.

A system for injecting includes a syringe body, a syringe interior, a syringe flange, and a stopper member and an injectable fluid disposed in the syringe interior. The system also includes a plunger member coupled to the stopper member. The system further includes a finger flange removably coupled to the syringe flange, the finger flange defining a pair of side openings and a pair of bumps adjacent respective side openings. Moreover, the system also includes a swing spacer rotatably coupled to the finger flange, the swing spacer defining a pair of arms, a pair of pivot pins, two pairs of slots, and a pair of indentations. The swing spacer is configured to define a distance of movement of the plunger member relative to the syringe body along a longitudinal axis of the syringe body, thereby defining a dose of the injectable fluid.

A syringe exostructure includes a main body which removably receives a syringe having a syringe barrel and a syringe plunger. A drive plunger is reciprocatably mounted on the main body, and a plunger bar is slidably received in an axial channel on the drive plunger. The plunger bar is configured to removably couple to the syringe plunger when the syringe is introduced into the main body. A drive pawl assembly is fixed to an upper surface of the drive plunger and transfers forward motion of the drive plunger to the plunger bar as the drive plunger is advanced and disengages from the plunger bar when the drive plunger is retracted. A locking pawl assembly is fixed to the main body and extends through a slot formed in the bottom of the axial channel in the drive plunger. The locking pawl engages the plunger bar and allows the plunger bar to be advanced by the drive plunger as the drive plunger is advanced but prevents the plunger bar from being retracted by the drive plunger as the drive plunger is retracted.

A medicament delivery device is disclosed having a housing, an actuation mechanism capable of delivering doses of medicament from a medicament container and arranged with a delivery member, a shield, a guard movable within the housing, wherein the guard is operably connected to the actuation mechanism. A protective cap is releasably arranged on the housing and having a shield remover. A blocking element on the guard is movable between a blocking position and a release position and has an engagement surface to engage a proximal area of the housing. The blocking element engages with a surface of the shield remover to retain the blocking element in the blocking position. The engagement surface causes a blocking of the guard from movement and removal of the protective cap enables a movement of the blocking element to a release position when the engagement surface engages the proximal area allowing the member guard to move.

An administration device for in particular intravitreal administration of a fluid, the administration device having a preferably pre-filled syringe and an actuation mechanism for actuating the syringe. The administration device preferably includes a priming device, in particular in addition to the actuation mechanism. It is preferably prevented that the priming device be advanced beyond a defined end position. The syringe can preferably be moved within a housing of the administration device and/or positioned completely inside the housing.

A discharger for discharging a predetermined amount of fluid from a separate container including a discharge section defining a longitudinal axis and having a proximal end and a distal end and having a discharge passage for the fluid extending between an inlet opening and an outlet opening of the discharge section. The discharger further includes an intermediate section including a distal portion cooperating with the proximal end of the discharge section and a proximal portion defining a receiving space which is adapted to be loaded with the separate container holding an amount of fluid to be discharged by the discharger. The distal portion and the proximal portion are formed in one piece and are interconnected by a breakable section.