A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.

A device for delivery of medicament is presented that has an elongated housing, a container mounted within the housing and adapted to contain liquid medicament, a stopper slidably arranged within said container, and a delivery mechanism comprising a resilient member, a plunger assembly having one end connected to the stopper and a second end being operably connected to the resilient member, a rotatable latch for releasably retaining the plunger assembly in a first position where the resilient member has an accumulated energy, where rotation of the latch releases the plunger assembly such that the accumulated energy is transferred to the plunger assembly for driving the stopper within the container whereby the medicament within said container is delivered to an injection site. After delivery of the medicament a rotator having a hard stop feature aligns with a rib on the protective shield to prevent retraction of the protective shield.

Described is a mixing syringe for receiving a removable carpule partitioned to form two reservoirs independently containing anesthetic solution and buffering solution and having a mixing chamber for mixing the solutions during administration, and methods of using the mixing syringe.

A multi-purpose automatic injector, comprising a base unit having a forward end and a rearward end and arranged along a longitudinal axis; a cartridge containing a medicament, the cartridge being coupled adjacent to the forward end of the base unit; a drive assembly attached to the base unit and configured to be actuated by a computerized controller; at least one piercing element configured to be operatively coupled with the drive assembly and configured to be movable by the drive member relative to the cartridge in a reciprocating manner upon receipt of a corresponding signal from the computerized controller.

The present disclosure relates to a drug delivery device having a case adapted to retain a medicament container, a plunger disposed within the case and slidable from a proximal position into a distal position for delivering a medicament from the medicament container, and at least one feedback mechanism that is in operative connection with the plunger. The feedback mechanism includes a collar, a needle shroud, and a control spring biasing the needle shroud in a distal direction relative to the collar. The collar is operatively coupled to the case in an axial direction and prevented from axially decoupling from the case by the plunger when in the proximal position. The plunger, during movement from the proximal position towards the distal position, allows axial decoupling of the collar from the case driven by the control spring until the collar's movement is halted, which creates an audible and/or tactile feedback.

Systems and methods of micro-infusion of medical fluids are disclosed. Micro-infusion systems may include a pump, a patient interface, tubing between the pump and the interface, and a micro-infusion device along the tubing. A first portion of the tubing above the micro-infusion device is longer than a second portion of the tubing below the device. The micro-infusion device may include a chamber in-line with the tubing, a first valve between the chamber and the first portion of the tubing, a second valve between the chamber and the second portion of the tubing and a third valve between the chamber and a dump chamber. The second valve may be slidably disposed within the chamber. A medical fluid may be provided into the chamber that slides the second valve displacing another fluid in the chamber through the third valve into the dump chamber.

An autoinjection device (10′) for expelling a dose of drug is described. A housing (300) movably holds a power unit (400, 500, 550, 700) configured for driving the piston of a held container (100), the power unit comprising: a) a plunger (500) comprising a retaining geometry (515), b) a drive spring (550) arranged in a tensed state wherein a first end portion of the drive spring (550) provides a distally directed force on the plunger (500), and c) a power base (400) operably coupled to the drive spring (550) and the plunger (500), the power base (400) grounding a second end portion of the drive spring (550), wherein, in a pre-firing state of the autoinjector, a retaining element (410, 415) of the power base (400) releasably engages the retaining geometry (515) of the plunger to retain the plunger against the force of the drive spring (550), wherein the autoinjection device (10′) further defines a user operable trigger element (700) cooperating with the retaining element (410, 415) to maintain retaining engagement with the retaining geometry (515) of the plunger until triggering, and further defines an electronic module (80′) comprising a sensor (850, 851) configured to sense the shift of position of the power base (400) as it moves upon triggering.

The present disclosure relates to a drug delivery device having a case adapted to retain a medicament container, a plunger disposed within the case and slidable from a proximal position into a distal position for delivering a medicament from the medicament container, and at least one feedback mechanism that is in operative connection with the plunger. The feedback mechanism includes a collar, a needle shroud, and a control spring biasing the needle shroud in a distal direction relative to the collar. The collar is operatively coupled to the case in an axial direction and prevented from axially decoupling from the case by the plunger when in the proximal position. The plunger, during movement from the proximal position towards the distal position, allows axial decoupling of the collar from the case driven by the control spring until the collar's movement is halted, which creates an audible and/or tactile feedback.

The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

The disclosure refers to a an assembly for a drug delivery device comprising: a housing having a proximal end and a distal end a longitudinal axis extending between the proximal end and the distal end, wherein the housing is adapted to receive and retain a drug reservoir and a needle, a needle cover which is movable between at least two different axial positions relative to the housing, a locking position and a non-locking position, wherein the needle cover has a needle cover locking feature which is arranged to block proximal movement of the needle cover relative to the housing in the locking position of the needle cover, wherein the needle cover has an outer surface delimiting an interior of the needle cover, and wherein the needle cover locking feature is disposed in the interior of the needle cover.