A drug injection device includes a last dose setting having a main drive pin, a drive wheel, a driven wheel, an abutment element fixedly coupled to, or integrally formed with, the driven wheel. The drive wheel has a rotation axis parallel to a longitudinal axis and is configured to be driven about the longitudinal axis by a knob and to be periodically driven in rotation about the rotation axis by the main drive pin, during a drug dose setting. The driven wheel has a second rotation axis parallel or coaxial to said longitudinal axis and is configured to be periodically driven about the longitudinal axis by the drive wheel. The abutment element is configured to prevent the rotation of the drive wheel about the longitudinal axis when the knob has made a predetermined number of full and/or partial rotations about the longitudinal axis correlated to the predetermined drug volume.

The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof.

The disclosure relates to a medicament delivery device, comprising a medicament cartridge adapted to contain a medicament and a stopper slidably arranged within the cartridge. The stopper-comprises a rigid body that is enclosed partially by a soft sealing component.

A handheld injection device (10) comprising an needle cannula, a reservoir configured for containing a liquid drug to be dispensed, a piston, a trigger button (22), an elongated, hollow outer housing (20) in which the reservoir is positioned, the needle cannula being in liquid communication with the reservoir and extending from one end of the housing, wherein the injection device further comprises a drive mechanism comprising a spring or a resilient member, the spring or a resilient member being configured to provide a driving force when the trigger button is pressed allowing the piston to be advanced by the drive mechanism thus causing a dose of the liquid drug to be dispensed, wherein the handheld injection device comprises a variable friction system being adapted to apply a variable counter force leveling out the driving force.

Disclosed herein are devices and methods for delivering a predetermined volume of a drug substance or other product including a fluid. An exemplary device may include a body configured to receive a drug substance therein, and a plunger rod disposed at least partially inside the body to distally move a stopper in the body. The device may include a component configured to regulate distal movement of the plunger rod in a priming step and in a subsequent delivery step, so that the device may be accurately primed and may accurately dispense a predetermined volume of a drug substance.

The present disclosure relates to a drug delivery device, comprising a housing, a cartridge, the cartridge containing a drug in a quantity sufficient for a plurality of doses of the drug, a bung, the bung being movably retained within the cartridge to dispense a dose of the drug from the cartridge upon movement of the bung with respect to the cartridge, and a drive mechanism, the drive mechanism being operable to transfer a driving force to the bung to dispense the dose of the drug from the cartridge. The drug delivery device is configured such that the maximal driving force which is transferrable to the bung via the drive mechanism varies and is adjusted to the current position of the bung within the cartridge.

The present disclosure is generally directed to a drive mechanism for use in a drug delivery device having a cylindrical cartridge, i.e. a handheld injection device for selecting and dispensing a number of user variable doses of a medicament. The drive mechanism includes a base element, a toothed piston rod, which is guided within and movable relative to the base portion, and a drive gear having a pinion, which is rotatably held in the base element and in meshed engagement with the toothed piston rod. The toothed piston rod includes multiple rigid rod pieces which are connected by hinges. The rigid rod pieces comprise a flat plate provided with a straight toothed rack.

Drive systems for a drug delivery device are provided. The drive systems can be positioned within a container that stores a liquid drug to be delivered to a user. The drive systems can be coupled to a plunger positioned within the container. The drive systems can be incrementally advanced to drive the plunger further into the container, thereby expelling a portion of the stored liquid drug from the container for delivery to the user. The container can be any type of container including a pre-filled, standardized drug cartridge. The drive systems and container can be components of a wearable drug delivery device.

The present invention relates to a torsion spring based automatic injection device for apportioning set doses of a liquid drug and which injection device is provided with an End-of-Dose feedback mechanism providing a user with an audible signal once the set dose has been injected. During injection, the scale drum rotates back to its “zero” position under influence of the torsion spring. This rotation is halted shortly before reaching the “zero” position by stopping means. The scale drum is thereafter only allowed to continue rotation and thus reach the “zero” position once the torque applied to the scale drum by the torsion spring surpasses a threshold value.

The present invention relates to a drug delivery device (100) comprising a housing (101), a threaded piston rod (102), a rotatable drive tube (103), a drive nut (104) in threaded engagement with the piston rod (102) and being rotationally locked but axially moveable relative to the drive tube (103), and a support member (105) arranged rotationally free on the piston rod (102), the support member (105) being axially locked relative to the housing (101) and arranged to allow the drive tube (103) to move axially. The device further comprises a compression drive spring (106) arranged between the piston rod (102) and the drive tube (103), the compression drive spring (106) being arranged axially between the drive nut (104) and the support member (105).