Needle assemblies for retractable needle syringes include a needle, a needle seal, and a needle retainer, wherein the needle includes one or more barbs substantially at its proximal end. The needle retainer engages an optional needle-over-mold component that is fixedly attached to the needle. The needle-over-mold may be connected to the distal surface of the needle seal and may travel, such as by being a couple component, with the needle during the operation of the syringe. A safety syringe includes a barrel having a needle assembly mounted at a distal end and a plunger assembly mounted at a proximal end. A drug may be contained in a drug chamber of barrel, between the plunger assembly and needle assembly, proximally of the needle seal for drug delivery to a user. The plunger assembly includes a plunger seal having a needle-engaging portion to capture the needle at the barb for retraction.

A medicament delivery device includes a main injection needle for injecting a medicament into the body of a patient. The medicament delivery device includes a pain reduction device for releasing a pain reduction agent into the body of the patient prior the medicament injection. The pain reduction device includes an array of microneedles.

A drug delivery device includes a reservoir, a drug delivery member in fluid communication with the reservoir, and a plunger disposed in and moveable relative to the reservoir. A plunger rod has a mass M.sub.P and is movable from (i) a first position, where the distal end of the plunger rod is spaced apart from the plunger to (ii) a second position, where the distal end of the plunger rod contacts the plunger. A drive mechanism is coupled to the proximal end of the plunger rod and is configured to deliver a drive force F.sub.D to move the plunger rod from the first position to the second position. A ratio of the mass of the plunger rod to the drive force of the drive mechanism (M.sub.P/F.sub.D) is in a range of approximately a value greater than 0 kg/kgf to approximately 0.05 kg/kgf.

A medicament delivery device may comprise a medicament chamber configured to hold a medicament, a plunger configured to move relative to the medicament chamber to expel the medicament from the medicament chamber, a pin configured to move from a first pin position wherein the pin prevents movement of the plunger to a second pin position wherein the pin allows movement of the plunger, an actuation assembly configured to move the pin from the first pin position to the second pin position, and a needle coupled to the medicament chamber. The medicament may flow through the needle from the medicament chamber to a user. The actuation assembly may be configured to automatically move the pin after a predetermined time delay.

A system for serially injecting liquids includes a syringe body, proximal and distal stopper members disposed in the syringe body, a first liquid in a distal chamber, a second liquid in a proximal chamber, a plunger member, and a needle hub assembly coupled to a distal needle interface of the syringe body. The plunger member includes a needle retention feature disposed in a plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. Manipulating the plunger member to insert the proximal stopper member distally relative to the syringe body initially expels the first liquid, then the second liquid. The needle is at least partially retractable into plunger interior.

A device for transferring fluids in a closed system transfer device using flash for last drop extraction and to reduce coring. The device including a piercing member having a distal end and a proximal end and defining a longitudinal fluid channel. A first opening positioned at the distal end of the piercing member wherein the first opening is in fluid communication with the longitudinal fluid channel. A cover or flash positioned over the first opening. The cover including a pre-cut pattern wherein the cover opens along the pre-cut pattern upon application of a distally directed force from the longitudinal fluid channel. The distal end including the first opening having a steep taper to facilitate last drop extraction.

A medical syringe having a forwardly projecting needle that is selectively retractable following use and also having a specially configured plunger handle and thumb cap that cooperate to form a concave pressure application surface (“CPAS”). The concave pressure application surface at the rear of the plunger handle enables the subject medical syringe to achieve functional advantages, each with an associated therapeutic benefit, that are not achieved with use of the prior art devices.

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially penetrated into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber; and an energy-storing member operatively coupled between the stopper member and the syringe body, the energy-storing member configured to facilitate retraction of the stopper member relative to the syringe body.

A catheter assembly and/or an introducer may include one or more features configured to guide a probe and/or a catheter distally through a septum. The catheter assembly may include a catheter adapter and the septum. The catheter adapter may include a distal end, a proximal end, and a lumen extending therebetween. In some embodiments, the septum may be disposed within the lumen. The septum may include a proximal surface that is tapered inwardly in a distal direction such that the proximal surface of the septum is configured to guide the probe and/or the catheter distally through the septum. The catheter assembly may be configured to receive an introducer, which may include an introducer element. A proximal end of the introducer element may include another proximal surface that is tapered inwardly in the distal direction such that the other proximal surface is configured to guide the probe or the catheter distally through the septum.

The present disclosure relates to an injection device including: a housing; a carrier disposed within the housing for holding a syringe that has a needle at one end; a needle sleeve located within the housing and being axially moveable with respect to the housing between an extended position and a retracted position; a biasing element configured to bias the needle sleeve towards the extended position; and a locking mechanism configured to lock the needle sleeve in the extended position after use of the injection device, the locking mechanism comprising; a first locking member provided on and projecting from the carrier; and a second locking member comprising a deflectable arm provided on the needle sleeve and moveable between a relaxed position and a deflected position.