A biological tissue transdermal patch houses a battery part and an active ingredient such that they do not come into contact with each other. For the use of the biological tissue transdermal patch, the battery part and the active ingredient are brought into contact to start battery reaction of the battery part and the battery part is attached to a biological tissue. Carbonized bacterial cellulose or cellulose nanofiber carbon is used for a positive electrode of the battery part.

Devices and methods for contactless delivery to a tissue of a subject using applied pulsed electric fields. The methods for controlling a therapy provided to a skin tissue of a subject using applied pulsed electric fields. The methods includes an jetting-nozzle assembly configured to not in directly contact with a skin tissue of a subject to deliver a series of electric field pulses to the skin tissue and a user input configured to receive an operational instruction for the series of electric field pulses. The operational instruction defines at least one of a pulse duration, a pulse frequency, a pulse number, and a pulse amplitude. The methods also includes at least one processor configured to access the operational instruction received by the user input and, using the operational instruction, create an electric field profile to be generated by the jetting-nozzle assembly about the skin tissue of the subject to control a cosmetic skin treatment.

Systems, apparatus, and methods are described for delivering a therapeutic substance to a target area within or proximate to a nasal cavity of a subject, including a reservoir configured to contain the therapeutic substance and a delivery interface by which the therapeutic substance is delivered to the target area. In some embodiments, systems, apparatus, and methods described herein can deliver a therapeutic substance using iontophoresis and/or electroosmosis.

An electrical discharge irrigation includes a power source to produce a first voltage, a circuit coupled to the power source to convert the first voltage to a second voltage, a discharge capacitor to receive the second voltage from the circuit, a transistor and/or a controlled rectifier coupled to the discharge capacitor to receive the second voltage, and an output tip. This tip is coupled to a transistor and/or a controlled rectifier and includes a first end, a second end, a longitudinal axis extending between them, an electrode located in an interior space of the tip to receive an electrical charge from the a transistor and/or a controlled rectifier and to release an electric discharge, and a ground return. The ground return is an outside surface of the tip. A space between the electrode and the ground return holds a conductive medium in contact with the electrode and the ground return.

An additional part for a hand-held device for electrically assisted skin treatment includes a ring which is clippable onto the hand-held device. The additional part further includes an absorbent carrier material where the absorbent carrier material is soaked with an active ingredient and where the absorbent carrier material is fastened to the ring.

An ophthalmic device including a hydrogel-based material body that can encapsulate a reservoir housing a therapeutic and a metal electrode covering the reservoir. The therapeutic can be delivered into an eye by way of electrodissolution of the metal electrode. The electrodissolution can be enhanced by the presence of chloride ions proximal to the metal electrode, and the ophthalmic device can be engineered to ensure the presence of chloride ions proximal to the metal electrode.

A device for delivering an ionic material includes a storage module including a reservoir configured to store the ionic material, a bipolar membrane configured to pass the ionic material in a single direction based on an ionic current, electrodes, disposed on a lower end of the reservoir and an upper end of the bipolar membrane, respectively, configured to form an electric field generating the ionic current, and a control module configured to control either one or both of a release amount and a release period of the ionic material passing through the bipolar membrane by adjusting a direction and an intensity of the electric field.

An additional part for a hand-held device for electrically assisted skin treatment includes a ring which is clippable onto the hand-held device. The additional part further includes an absorbent carrier material where the absorbent carrier material is soaked with an active ingredient and where the absorbent carrier material is fastened to the ring.

Systems, apparatus, and methods are described for delivering a therapeutic substance to a target area within or proximate to a nasal cavity of a subject, including a reservoir configured to contain the therapeutic substance and a delivery interface by which the therapeutic substance is delivered to the target area. In some embodiments, systems, apparatus, and methods described herein can deliver a therapeutic substance using iontophoresis and/or electroosmosis.

Delivering an anesthetizing solution into the ear canal. One example embodiment is a method of treatment, the method comprising: adhering a pad to a patient, the adhering on the patients face proximate to a tragus of the patient, and the pad being a member of an earset assembly; inserting an earset into an ear canal of the patient; locking relative orientations of the earset and pad by way of a connection assembly, the locking in place to hold the earset in the ear canal; filling the ear canal with therapeutic fluid; and performing iontophoresis with the therapeutic fluid by way of an electrode of the earset.