An automated wearable belt cardiac defibrillator (BCD) for wearing by a subject, comprising: at least two patches adapted for adhering to the subject each comprising a defibrillation electrode and an ECG sensor; and a BCD controller connected to each of the patches, wherein the patches comprise an adhesive adapted for long-term adhering of the patches to the subject, wherein the adhesive is a biocompatible adhesive, wherein the patches and adhesive are adapted for movement of the subject while the patches are adhered to the subject, wherein the patches are replaceable, wherein the controller is housed in a belt for wearing by the subject, wherein the belt is adapted for being flexible, wherein the adaptation for being flexible comprises a plurality of compartments for housing components of the controller, wherein a method for usage of the BCD comprises: following completion of an operational period, positioning of the patches to alternative locations on the subject wherein each of the alternate locations represents an alternate shock vector.

Improved hydrogel configurations for use with a TTField-generating system is disclosed. Also disclosed are kits containing the improved hydrogel configurations and methods of producing and using the improved hydrogel configurations.

An earpiece includes an earbud that supports at least one electrode, and an ear tip that includes a hydrogel. The ear tip is configured to be coupled to the earbud such that the hydrogel overlies the at least one electrode and such that the hydrogel is disposed between the at least one electrode and the user's skin when the earpiece is worn.

A system and method for delivering TTFields are herein described. The system comprises an electric field generator generating a signal having a frequency from 50 kHz to 1 MHz and coupled to a lead. A pad is coupled to the lead and includes a solid continuous phase material and a conductive gel. The solid continuous phase material receives the signal from the lead, has a skin-facing surface, and is constructed of a conductive material or has a conductive material attached to, absorbed into, or adsorbed onto the solid continuous phase material. Pockets intersect the skin-facing surface, the pockets sized and dimensioned to receive a hair shaft. The conductive gel is attached to, absorbed into, or adsorbed onto the skin-facing surface and positioned within some of the pockets.

A wound treatment device includes a flexible substrate having a top side, a bottom side and an opening extending therebetween. A reservoir has a port in fluid communication with the opening, and an iontophoretic driver circuit is electrically coupled to a plurality of electrodes.

One embodiment of the present invention provides a flexible neural electrode having improved adherence to an object by using a three-dimensional structure. A neural electrode based on the three-dimensional structure of a flexible substrate, according to one embodiment of the present invention, comprises: a first polymer layer, which is formed from a polymer material, is flexible, and functions as a base; at least one photoresist part, which is formed on one portion of the surface of the first polymer layer and forms a three-dimensional structure; a second polymer layer which is formed on the photoresist part and the rest of the surface of the first polymer layer, and which comprises protrusion parts caused by the photoresist part; a metal thin film layer formed by patterning a metal thin film on the surface of the second polymer layer and the surface of the protrusion parts; and a third polymer layer which is formed on the surface of the second polymer layer and the metal thin film layer so as to function as a covering, and which comprises measurement holes formed so that one portion of the metal thin film layer formed at the ends of the protrusion parts is exposed to the outside.

This document describes a conformable substrate that includes a hydrogel having adhesion-promoting moieties, said adhesion-promoting moieties comprising one or more catechol groups. The conformable substrate includes an array of microelectrodes bonded to the hydrogel by the adhesion-promoting moieties via the one or more catechol groups. This document also describes a method for transfer printing of an electronic structure to a hydrogel. The method includes the steps of coating a donor substrate with a film of polyacrylic acid, crosslinking the film of polyacrylic acid in a solution comprising divalent ions, patterning a microelectrode array onto the crosslinked film of polyacrylic acid, laminating an adhesive hydrogel substrate onto the donor substrate coated by the crosslinked film of polyacrylic acid comprising the patterned microelectrode array, and separating the crosslinked film of polyacrylic acid from the donor substrate in a monovalent solution.

The present disclosure relates to a method for increasing an amount of air and/or oxygen passing through an airway of an individual, reducing airway restrictions in an individual, increasing airway patency and/or maintaining airway patency in an individual, decreasing snoring, obstructive sleep apnea, or a combination thereof, in an individual. The method may comprise stimulating at least four regions of the individual's neck, where two of the at least four regions of the individual's neck are anterior triangle regions on opposing sides of the individual's midline, and another two of the at least four regions of the individual's neck are anterior triangle regions on opposing sides of the individual's midline, posterior to the two of the at least four regions. The present disclosure also discusses related devices and systems.

A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.

The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.