The lead implanted in a body to apply electrical stimulation to body organs may include: an electrode wire having one end provided as an insertion portion to be inserted into a body and the other end provided as an interface portion for connection with an external device to transmit a stimulation signal: a plurality of first electrodes in the insertion portion; a plurality of second electrodes on the interface portion; and a plurality of signal lines interconnecting the first electrodes and the second electrodes, wherein the insertion portion of the electrode wire includes a plurality of support portions on which the first electrodes are respectively disposed and a plurality of stretchable portions between the support portions and expandable and contractible, and further includes an operation unit for pushing or pulling each support portion in a longitudinal direction of the electrode wire to adjust a position of the support portion.

A lead structure includes a lead having an electrode wire having one end provided as an insertion portion to be inserted into a body and the other end provided as an interface portion for connection with an external device, a first electrode in the insertion portion to transmit electrical stimulation to body organs, a second electrode on the interface portion to receive electrical stimulation applied from outside, and a signal line configured to interconnect the first electrode and the second electrode and transmit the electrical stimulation received by the second electrode to the first electrode; and a lead case configured to surround the lead, and a conductive plate configured to apply electrical stimulation to body organs and a support plate configured to provide electrical stimulation from the first electrode to the conductive plate by contacting the first electrode.

A lead implanted in a body to apply electrical stimulation to body organs includes an electrode wire having one end provided as an insertion portion to be inserted into a body and another end provided as an interface portion for connection with an external device; a first electrode in the insertion portion to transmit electrical stimulation to body organs; a second electrode on the interface portion to receive electrical stimulation applied from outside; a signal line that interconnects the first electrode and second electrode to transmit electrical stimulation received by the second electrode to the first electrode; and a ring member that covers the first electrode and has an opening for exposing the first electrode in a portion of a circumferential direction, and is mounted to be movable in a longitudinal or circumferential direction with respect to the electrode wire by an external force to adjust an exposure position of the first electrode.

The present disclosure relates to thin-film lead assemblies and neural interfaces with stent-assisted deployment, and methods of microfabricating thin-film lead assemblies and neural interfaces. Particularly, aspects of the present disclosure are directed to a medical device having a thin-film neural interface, a stent, and a cable. The thin-film neural interface includes a first supporting structure, electrodes formed on the first supporting structure, and an encapsulation material encasing a portion of the first supporting structure. The cable includes a second supporting structure, conducive traces formed on the second supporting structure and electrically connected with the electrodes, and the encapsulation material encasing at least a portion of the second supporting structure. The stent is at least partially embedded in the encapsulation material encasing the portion of the first supporting structure, and the thin-film neural interface is helically wrapped around at least a portion of the stent.

The present disclosure discusses a method of manufacturing an implantable neural electrode. The method includes cutting a metal layer to form a plurality of electrode sites, contact pads and metal traces connecting the electrode sites to the contact pads. A first silicone layer including a mesh is formed and coupled to the metal layer. A second silicone layer is formed and laminated to the first silicone layer coupled with the metal layer. Holes are formed in the first or second silicone layer exposing the contact pads and electrode sites. Wires are welded to the exposed contact pads and a third layer of silicone is overmolded over the contact pads and wires.

Methods, devices, and systems induce neuromodulation by focusing a source of stimulation through a skull/brain interface in the form of an aperture formed in the skull, a naturally occurring fenestration in the skull, or a transcranial channel. Methods, devices, and systems identify where to locate skull/brain interfaces, accessories that can be used with the interfaces, and features for controlling stimulation delivered through the interfaces. Multiple indications for the skull/brain interfaces include diagnosis and treatment of neurological disorders and conditions such as epilepsy, movement disorders, depression, Alzheimer's disease, autism, coma, and pain.

Aspects of the disclosure include a bio-electric stimulation probe assembly including a patch including a first aperture and also a guide socket including a grommet and a second aperture. The guide socket is positioned on the patch such that the first and second apertures are aligned. The assembly further includes a guide including a tip that is positioned within and rotatable within the grommet. A probe of the assembly having at least one electrode is interconnected with the guide and extends through the first and second apertures. The guide and guide socket are collectively arranged and configured so that the guide has three degrees of rotational freedom with respect to the grommet thus meaning the probe correspondingly has three degrees of rotational freedom with respect to the grommet. Methods of using stimulation probe assemblies are also disclosed.

A burr hole cover includes a cap or cap assembly and a retainer and is configured to be partially positioned within a burr hole formed in a patient. The retainer has a cap-receiving aperture; a plurality of grooves provided in the retainer and a plurality of cut-outs wherein each cut-out is provided at an end of each groove towards the outer perimeter of the retainer. A channel may be provided at an opposite end of each groove vertically-extending from the top to the bottom of the retainer to encourage a medical device segment to remain in a groove during installation of the burr hole cover. The burr hole cover may be used to secure segments of medical devices relative to a burr hole and to allow a range of lateral motion for the portion(s) of the medical device(s) extending proximally out of the corresponding groove.

A skull-mountable medical device is disclosed. The device includes a housing containing a light source for providing phototherapy to a patient. A light pipe is attached to the housing. The device is configured to be positioned on a patient's skull with the light pipe extending into the patient's brain, such that light from the light source can irradiate a target position within the patient's brain. Once so positioned, the housing may be affixed to the skull via bone screws. The device is powered and controlled by an implantable pulse generator (IPG) that may be implanted into a patient's tissue remotely from the device and connected to the device by wire leads.

An implantable medical device for providing phototherapy to a patient's brain is disclosed. The device includes a housing containing a light source for providing phototherapy to a patient. A light path is attached to the housing. The implantable medical device is configured to be positioned between a patient's skull and scalp with the light path extending into the patient's brain, such that light from the light source can irradiate a target position within the patient's brain. The implantable medical device is powered and controlled by an implantable pulse generator (IPG) that may be implanted into a patient's tissue remotely from the device and connected to the device by wire leads.